User:Omar F. Khan

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Omar F. Khan

Omar F. Khan

Hi, my name is Omar F. Khan, and I'm currently at the Massachusetts Institute of Technology in Professor Robert Langer's lab within the David H. Koch Institute for Integrative Cancer Research. I did my PhD at the University of Toronto under the supervision of Professor Michael V. Sefton.

I work towards the treatment of damaged tissues and organs by combining nanotechnology and tissue engineering. I learned about OpenWetWare from Professor Axel Guenther and served with him on the Toronto Microfluidic Foundry's Process Technology Committee. I've joined because I fabricate microfluidic devices. You can email me through OpenWetWare.


Postdoctoral Associate, Langer Lab, Massachusetts Institute of Technology


Ph.D., Chemical Engineering and Applied Chemistry/Institute of Biomaterials and Biomedical Engineering, University of Toronto, 2010

B.A.Sc.(with honors), Chemical Engineering, University of Toronto, 2004

Publications and Communications

Khan O.F., Chamberlain M.D. and Sefton M.V. Toward an In Vitro Vasculature: Differentiation of Mesenchymal Stromal Cells Within an Endothelial Cell-Seeded Modular Construct in a Microfluidic Flow Chamber. Tissue Engineering Part A, 2011 Dec 2. [Epub ahead of print]

Khan, O.F. and Sefton, M.V. Endothelialized biomaterials for tissue engineering applications in vivo. Trends in Biotechnology, 2011 Aug;29(8):379-87.

Khan, O.F. and Sefton, M.V. Patterning Collagen/Poloxamine-Methacrylate Hydrogels for Tissue-Engineering-Inspired Microfluidic and Laser Lithography Applications. Journal of Biomaterial Science, DOI: 10.1163/092050610X540693, Epub ahead of print

Chamberlain, M.D., Butler, M.J., Ciucurel, E.C., Fitzpatrick, L.E., Khan, O.F., Leung, B.M., Lo, C., Patel, R., Velchinskaya, A., Voice, D.N. and Sefton, M.V. Fabrication of Micro-Tissues using Modules of Collagen Gel Containing Cells. Journal of Visualized Experiments, DOI: 10.3791/2177

Khan, O.F. and Sefton, M.V. Endothelial Cell Behaviour within a Microfluidic Mimic of the Flow Channels of a Modular Tissue Engineered Construct. Biomedical Microdevices, 2011 Feb;13(1):69-87.

Khan, O.F. and Sefton, M.V. Perfusion and Characterization of an Endothelial Cell-Seeded Modular Tissue Engineered Construct Formed in a Microfluidic Remodeling Chamber. Biomaterials, 2010 Nov;31(32):8254-61

Khan, O.F., Jean-Francois, J. and Sefton, M.V. MMP Levels in the Response to Degradable Implants in the Presence of a Hydroxamate-Based Matrix Metalloproteinase Sequestering Biomaterial In Vivo. Journal of Biomedical Materials Research, Part A, 2010 Jun 15;93(4):1368-79.

Sosnik A., Khan O.F., Butler M, Sefton M.V.: Poloxamine hydrogels: From non-cell adhesive substrates to matrices with improved cytocompatibility for Tissue Engineering applications. In Barbucci, R. (Ed.), Hydrogels: Biological Properties and Applications. Springer; 2009.

Khan, O.F., Chamberlain, M.D., Dahlman, J.E., Sefton, M.V., Langer, R.S. and Anderson, D.G. "Modular Tissue Containing Endothelial and Mesenchymal Stem Cells formed in a Microfluidic Perfusion Chamber." The 11th US-Japan Symposium on Drug Delivery Systems Conference, Lahaina, Maui, USA, December 16-20, 2011. Poster Presentation

Voice, D.N., Khan, O.F., Leung, B.M. and Sefton, M.V. “High throughput module production and applications to cardiac tissue engineering.” Ontario-on-a-Chip, Toronto, Ontario, Canada, June 9-10, 2011. Poster Presentation

Voice, D.N., Khan, O.F., Leung, B.M. and Sefton, M.V. “A novel plug flow process for high throughput modular tissue engineering.” Canadian Biomaterials Society, 29th Annual Conference, Vancouver, British Columbia, Canada, June 1-4, 2011. Oral presentation

Khan, O.F., Chamberlain, M.D. and Sefton, M.V. “Modular Tissue Containing Endothelial Cells and Mesenchymal Stem Cells formed in a Microfluidic Perfusion Chamber.” Tissue Engineering and Regenerative Medicine International Society (TERMIS)-European Union Chapter Meeting, Galway, Ireland, June 13-17, 2010. Oral Presentation

Khan, O.F., Leung, B.M. and Sefton, M.V. “Modular Cardiac Tissue Containing Endothelial and Cardiomyocyte Cells formed in a Microfluidic Perfusion Chamber,” Ontario-on-a-Chip, Toronto, ON., Canada, May 20-21, 2010. Oral Presentation

Khan, O.F. and Sefton, M.V. “Collagen/Poloxamine Microfluidic Flow Circuits to Characterize Surface-Attached Endothelial Cells Under Flow.” 8th World Biomaterials Congress, Amsterdam, The Netherlands, May 28-June 1, 2008. Oral Presentation

Khan, O.F. and Sefton, M.V. “In Vivo Use of a Matrix Metalloproteinase-Sequestering Biomaterial to Alter the Inflammatory Response,” Regenerate World Congress on Tissue Engineering and Regenerative Medicine, Pittsburgh, Pennsylvania, USA, April 23-27, 2006. Poster Presentation

Khan, O.F. and Sefton, M.V. “In Vivo Alteration of the Foreign Body Response Using a Matrix Metalloproteinase-Sequestering Biomaterial,” Challenges in Regenerative Medicine (ChaRM), Toronto, Ontario, Canada, October 20-21, 2005. Poster Presentation

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Editing pages:Here's an extensive list of formating examples. Or look at this OpenWetWare introductory tutorial. For examples, check out User:Julius_B._Lucks, User:Jason_R._Kelly and User:Reshma_P._Shetty.