User:Nikolai Eroshenko
Research
I am building new technologies for basic and applied biology. Long-term research interests include:
- human transgene vectors that integrate genes into precise locations on the genome
- cheaper, faster, and more accurate gene synthesis
- library vs. library screens which quantify the strength of protein-protein and protein-DNA interactions
Publications
5. Nikolai Eroshenko*, Rukmani Ramachandran*, Vamsi Yadavalli, Raj R. Rao (2013) Effect of substrate stiffness on early human embryonic stem cell differentiation. J Biol Eng 7:7 4. Shilpa Iyer, Ena Xiao, Khaled Alsayegh, Nikolai Eroshenko, Marion J. Riggs, James P. Bennett. Jr & Raj R. Rao (2012) Mitochondrial gene replacement in human pluripotent stem cell derived neural progenitors. Gene Ther 19:469 3. Nikolai Eroshenko*, Sriram Kosuri*, Adam H. Marblestone, Nicholas Conway, George Church (2012) Gene assembly from chip-synthesized oligonucleotides. Curr Prot Chem Biol 4:1 2. Sriram Kosuri*, Nikolai Eroshenko*, Emily LeProust, Michael Super, Jeffrey Way, Jin Billy Li & George Church (2010) Scalable gene synthesis by selective amplification of DNA pools from high-fidelity microchips. Nat Biotechnol 28:1295 1. Sheena Abraham, Nikolai Eroshenko & Raj R. Rao (2009) Role of bioinspired polymers in determination of pluripotent stem cell fate. Regen Med 4:561
Patents
1. George Church, Sriram Kosuri, Nikolai Eroshenko (pending) Orthogonal amplification and assembly of nucleic acid sequences US Patent App 2011057075 (Harvard)
Labs
George Church (2009-now)
Wyss Institute (2009-2011)
Raj Rao (2006-2008)
Curtis Taylor (2006-2007)
Education
Harvard University (2008-now) PhD candidate, Bioengineering
Virginia Commonwealth University (2005-2008) BS, Biomedical Engineering
Contact
eroshenkona AT gmail
Nikolai Eroshenko
77 Ave. Louis Pasteur
NRB 238
Boston, MA 02115