User:Modesto Redrejo Rodríguez

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Contact Info

Modesto Redrejo Rodriguez (Simpson's interpretation)
  • Modesto Redrejo Rodriguez, PhD

Phi29 Laboratory
Severo Ochoa Molecular Biology Center

Nicolás Cabrera, 1
28049 - Madrid
SPAIN

Education

  • 2009, PhD, Universidad Autónoma de Madrid
  • 2005, MS, Universidad Autónoma de Madrid
  • 2002, BS, Universidad de Extremadura

Research interests

  1. DNA replication
  2. DNA damage and repair
  3. Base excision and nucleotide incision repair pathways
  4. AP endonucleases and DNA Glycosylases
  5. Mutagenic agents
  6. DNA virus genome maintenance
  7. Redox modulation of enzyme activities
  8. Disulfide bonds

Publications

  1. Gelin A, Redrejo-Rodríguez M, Laval J, Fedorova OS, Saparbaev M, and Ishchenko AA. Genetic and biochemical characterization of human AP endonuclease 1 mutants deficient in nucleotide incision repair activity. PLoS One. 2010 Aug 17;5(8):e12241. DOI:10.1371/journal.pone.0012241 | PubMed ID:20808930 | HubMed [paper6]
    DNA Base excision repair
  2. Rodríguez I, Nogal ML, Redrejo-Rodríguez M, Bustos MJ, and Salas ML. The African swine fever virus virion membrane protein pE248R is required for virus infectivity and an early postentry event. J Virol. 2009 Dec;83(23):12290-300. DOI:10.1128/JVI.01333-09 | PubMed ID:19793823 | HubMed [Paper5]
  3. Redrejo-Rodríguez M, Ishchenko AA, Saparbaev MK, Salas ML, and Salas J. African swine fever virus AP endonuclease is a redox-sensitive enzyme that repairs alkylating and oxidative damage to DNA. Virology. 2009 Jul 20;390(1):102-9. DOI:10.1016/j.virol.2009.04.021 | PubMed ID:19464038 | HubMed [Paper4]
  4. Redrejo-Rodríguez M, García-Escudero R, Yáñez-Muñoz RJ, Salas ML, and Salas J. African swine fever virus protein pE296R is a DNA repair apurinic/apyrimidinic endonuclease required for virus growth in swine macrophages. J Virol. 2006 May;80(10):4847-57. DOI:10.1128/JVI.80.10.4847-4857.2006 | PubMed ID:16641276 | HubMed [Paper3]
  5. Rodríguez I, Redrejo-Rodríguez M, Rodríguez JM, Alejo A, Salas J, and Salas ML. African swine fever virus pB119L protein is a flavin adenine dinucleotide-linked sulfhydryl oxidase. J Virol. 2006 Apr;80(7):3157-66. DOI:10.1128/JVI.80.7.3157-3166.2006 | PubMed ID:16537584 | HubMed [Paper2]
    My work in ASFV
All Medline abstracts: PubMed | HubMed

No PubMed papers:

1. Modesto Redrejo-Rodriguez, Adrian Tejeda-Cano, Maria del Carmen Pinto, Pedro Macías.
Lipoxygenase inhibition by flavonoids: semiempirical study of the structure–activity relationship
Journal of Molecular Structure: THEOCHEM, Volume 674, Issues 1-3, April 2004, Pages 121-124 [Paper1]


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