User:Matthew R Lockett

Matthew R Lockett (an artistic interpretation)

• Matthew R Lockett

Research Assistant Department of Chemistry University of Wisconsin - Madison 1101 University Avenue Madison, WI 53706

Part-time Chemistry Instructor Madison Area Technical College

• Email me through OpenWetWare

I work in the LMS at the University of Wisconsin-Madison. I learned about OpenWetWare from epernicus, and I've joined because None specified.

Education

• PhD in Progress, University of Wisconsin-Madison
• 2004, BS in Chemistry, University of Pittsburgh

Research interests

1. Developing new surface chemistries for the fabrication of small molecule/biomolecule arrays on carbanaceous materials (i.e. amorphous carbon, glassy carbon, diamond, etc)
2. Identifying small molecule-protein, DNA-protein, and protein-protein interactions with SPR and MALDI-MS
3. Metabolomic profiling procedures

Publications

1. Lockett MR, Shortreed MR, and Smith LM. Aldehyde-terminated amorphous carbon substrates for the fabrication of biomolecule arrays. Langmuir. 2008 Sep 2;24(17):9198-203. DOI:10.1021/la800991t |
2. Lockett MR, Weibel SC, Phillips MF, Shortreed MR, Sun B, Corn RM, Hamers RJ, Cerrina F, and Smith LM. Carbon-on-metal films for surface plasmon resonance detection of DNA arrays. J Am Chem Soc. 2008 Jul 9;130(27):8611-3. DOI:10.1021/ja802454c |
3. Phillips MF, Lockett MR, Rodesch MJ, Shortreed MR, Cerrina F, and Smith LM. In situ oligonucleotide synthesis on carbon materials: stable substrates for microarray fabrication. Nucleic Acids Res. 2008 Jan;36(1):e7. DOI:10.1093/nar/gkm1103 |
4. Lockett MR, Phillips MF, Jarecki JL, Peelen D, and Smith LM. A tetrafluorophenyl activated ester self-assembled monolayer for the immobilization of amine-modified oligonucleotides. Langmuir. 2008 Jan 1;24(1):69-75. DOI:10.1021/la702493u |
5. Lee JE, Didier DN, Lockett MR, Scalf M, Greene AS, Olivier M, and Smith LM. Characterization of vascular endothelial growth factor receptors on the endothelial cell surface during hypoxia using whole cell binding arrays. Anal Biochem. 2007 Oct 15;369(2):241-7. DOI:10.1016/j.ab.2007.06.010 |
6. Lockett MR, Shortreed MR, and Smith LM. Molecular beacon-style hybridization assay for quantitative analysis of surface invasive cleavage reactions. Anal Chem. 2007 Aug 1;79(15):6031-6. DOI:10.1021/ac070424c |
7. Sun B, Colavita PE, Kim H, Lockett M, Marcus MS, Smith LM, and Hamers RJ. Covalent photochemical functionalization of amorphous carbon thin films for integrated real-time biosensing. Langmuir. 2006 Nov 7;22(23):9598-605. DOI:10.1021/la061749b |

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