User:Mateo

Matthew Wallace Department of Chemistry 32 Vassar St. 18-425 Cambridge, MA 02445 wallacem@mit.edu

Hello, I am Matt in the Lippard Lab at MIT.

Research Interests

• The biological mechanism behind cisplatin's anti-cancer properties

Education

2006 - Present: Postdoctoral Researcher, Bioinorganic Chemistry, MIT
2005: Ph.D., Biochemistry and Molecular Biology, University of California, Los Angeles (UCLA)

1999: B.S., Biochemistry, University of California, Davis (UC Davis)

Publications

1. Sanchez RJ, Srinivasan C, Munroe WH, Wallace MA, Martins J, Kao TY, Le K, Gralla EB, and Valentine JS. Exogenous manganous ion at millimolar levels rescues all known dioxygen-sensitive phenotypes of yeast lacking CuZnSOD. J Biol Inorg Chem. 2005 Dec;10(8):913-23. DOI:10.1007/s00775-005-0044-y |
2. Wallace MA, Bailey S, Fukuto JM, Valentine JS, and Gralla EB. Induction of phenotypes resembling CuZn-superoxide dismutase deletion in wild-type yeast cells: an in vivo assay for the role of superoxide in the toxicity of redox-cycling compounds. Chem Res Toxicol. 2005 Aug;18(8):1279-86. DOI:10.1021/tx050050n |
3. Wallace MA, Liou LL, Martins J, Clement MH, Bailey S, Longo VD, Valentine JS, and Gralla EB. Superoxide inhibits 4Fe-4S cluster enzymes involved in amino acid biosynthesis. Cross-compartment protection by CuZn-superoxide dismutase. J Biol Chem. 2004 Jul 30;279(31):32055-62. DOI:10.1074/jbc.M403590200 |
4. Lindsay LL, Wallace MA, and Hedrick JL. A hatching enzyme substrate in the Xenopus laevis egg envelope is a high molecular weight ZPA homolog. Dev Growth Differ. 2001 Jun;43(3):305-13. DOI:10.1046/j.1440-169x.2001.00577.x |