User:Liuzhec

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Project Overview

  • Our goal is to design and implement molecular containers, which can be dynamically opened and closed by an external stimulus.
  • The containers will be implemented as DNA nanostructures, which afford a significant degree of positional control and chemical versatility.
  • As an initial proof-of-concept, we plan to use our DNA containers to demonstrate controllable activation ("delivery") of anti-thrombin aptamers.
  • We expect that molecular containers could have several interesting scientific and clinical applications, such as
    • Drug and gene delivery
    • Bio-marker scavenging (early detection of biomarkers)
    • Directed evolution (compartmentalized selections)
    • Using multiplexing for combinatorial chemical synthesis
    • Capture and stabilization of multiprotein complexes
    • Protein folding (chaperones)
    • Cell sorting

==Working Team Members== edit

Recent Changes

17 October 2017

     12:35  User:Dominique Brager/Notebook/481 Notebook/2017/09/27‎ (diff | hist) . . (-42). . Dominique Brager (talk | contribs) (Data)
     12:35  User:Dominique Brager/Notebook/481 Notebook/2017/09/26‎ (diff | hist) . . (+2). . Dominique Brager (talk | contribs) (Objective)

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(Upload log). .

[Mackenzie K. Kelley‎ (2×); Dominique Brager‎ (8×)]

     

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. . Mackenzie K. Kelley (talk | contribs) uploaded File:Screen Shot 2017-10-17 at 3.34.32 PM.png

     

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. . Dominique Brager (talk | contribs) uploaded File:CysAuNP-HdMe2ImCl.png

     

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. . Dominique Brager (talk | contribs) uploaded File:BSAAuNP-Glycine.png

     

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. . Mackenzie K. Kelley (talk | contribs) uploaded File:Screen Shot 2017-10-17 at 2.30.38 PM.png

     12:35  User:Dominique Brager/Notebook/481 Notebook/2017/09/20‎ (diff | hist) . . (+4). . Dominique Brager (talk | contribs) (Objective)

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User:Dominique Brager/Notebook/481 Notebook/2017/09/19‎‎ (4 changes | history) . . (-32). . [Dominique Brager‎ (4×)]

     

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(cur | prev) . . (-1). . Dominique Brager (talk | contribs) (Objective)

     

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     12:33  User:Dominique Brager/Notebook/481 Notebook/2017/09/13‎ (diff | hist) . . (+927). . Dominique Brager (talk | contribs) (Data)
     11:32  User:Mackenzie K. Kelley/Notebook/Experimental Biochemistry/2017/09/26‎ (diff | hist) . . (+49). . Mackenzie K. Kelley (talk | contribs) (Results)
     11:15  User:Rollinsr‎ (diff | hist) . . (+44). . Rollinsr (talk | contribs) (Rick Rollins Discussion Page)
     11:14  User:Mackenzie K. Kelley/Notebook/Experimental Biochemistry/2017/10/17‎ (diff | hist) . . (+659). . Mackenzie K. Kelley (talk | contribs) (Entry title)

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Biomod/2017/StJohns:Results‎‎ (2 changes | history) . . (-9,035). . [Alexkk15‎ (2×)]

     

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     10:37  User:Changx‎ (diff | hist) . . (+771). . Changx (talk | contribs) (Potholes and Identifiers)

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User:Jamesonn‎‎ (3 changes | history) . . (+386). . [Jamesonn‎ (3×)]

     

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User:Douglas M. Fox/Notebook/AU CHEM-571 F2011 Lab Support/2017/10/17‎‎ (4 changes | history) . . (+1,666). . [Douglas M. Fox‎ (4×)]

     

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(cur | prev) . . (+86). . Douglas M. Fox (talk | contribs) (Tasklist)

     

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(cur | prev) . . (+950). . Douglas M. Fox (talk | contribs) (Autocreate 2017/10/17 Entry for User:Douglas_M._Fox/Notebook/AU_CHEM-571_F2011_Lab_Support)

     09:09  CONJ606:Materials‎ (diff | hist) . . (+72). . Jamesonn (talk | contribs)
     08:44  Rich Lab:Important Lab Documents‎ (diff | hist) . . (0). . Isabel C. Morales (talk | contribs) (Lab Contact List)

16 October 2017

     20:17  User:Kromine‎ (diff | hist) . . (+435). . Kromine (talk | contribs) (Kyle Romine's Discussion Page)

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Hoatlin:OHSU Genetic Mechanisms Class‎‎ (2 changes | history) . . (+12). . [Maureen E. Hoatlin‎ (2×)]

     

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(cur | prev) . . (+7). . Maureen E. Hoatlin (talk | contribs) (Other Bonus Material)

     

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User:Maryam Yamadi/Notebook/Experimental Biological Chemistry I/2017/10/11‎‎ (2 changes | history) . . (+968). . [Maryam Yamadi‎ (2×)]

     

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(cur | prev) . . (+18). . Maryam Yamadi (talk | contribs) (10/11 Lab Notebook)

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(cur | prev) . . (+950). . Maryam Yamadi (talk | contribs) (Autocreate 2017/10/11 Entry for User:Maryam_Yamadi/Notebook/Experimental_Biological_Chemistry_I)

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(Upload log). .

[Maryam Yamadi‎ (4×)]

     

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User:Maryam Yamadi/Notebook/Experimental Biological Chemistry I/2017/10/04‎‎ (2 changes | history) . . (+968). . [Maryam Yamadi‎ (2×)]

     

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User:Maryam Yamadi/Notebook/Experimental Biological Chemistry I/2017/10/03‎‎ (2 changes | history) . . (+968). . [Maryam Yamadi‎ (2×)]

     

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(cur | prev) . . (+18). . Maryam Yamadi (talk | contribs) (10/03 Lab Notebook)

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(cur | prev) . . (+950). . Maryam Yamadi (talk | contribs) (Autocreate 2017/10/03 Entry for User:Maryam_Yamadi/Notebook/Experimental_Biological_Chemistry_I)

N    15:09  User:Maryam Yamadi/Notebook/Experimental Biological Chemistry I/2017/10‎ (diff | hist) . . (+202). . Maryam Yamadi (talk | contribs) (Autocreate Month 2017/10 Entry for User:Maryam_Yamadi/Notebook/Experimental_Biological_Chemistry_I)
     15:05  User:Maryam Yamadi/Notebook/Experimental Biological Chemistry I/2017/09/27‎ (diff | hist) . . (+18). . Maryam Yamadi (talk | contribs) (09/27 Lab Notebook)




Welcome to Harvard's 2006 iGEM team wiki! Please click on the project of interest for up to date information and current progress. Igem2006logo.gif




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DNA Nanostructures
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Harvard 2006 iGem team.

Back row (L-R): Lewis, Katie, Tiffany, Valerie, Zhipeng, Matt.
Front row (L-R): Hetmann, Jeffrey, David, Perry.

And yes, that is the back end of a bronze rhinoceros.

.

A thanks goes to MIT's team page for our page formatting.