User:Liuzhec
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Project Overview
- Our goal is to design and implement molecular containers, which can be dynamically opened and closed by an external stimulus.
- The containers will be implemented as DNA nanostructures, which afford a significant degree of positional control and chemical versatility.
- As an initial proof-of-concept, we plan to use our DNA containers to demonstrate controllable activation ("delivery") of anti-thrombin aptamers.
- We expect that molecular containers could have several interesting scientific and clinical applications, such as
- Drug and gene delivery
- Bio-marker scavenging (early detection of biomarkers)
- Directed evolution (compartmentalized selections)
- Using multiplexing for combinatorial chemical synthesis
- Capture and stabilization of multiprotein complexes
- Protein folding (chaperones)
- Cell sorting
==Working Team Members== {edit}
- Tiffany Chan (talk, edits)
- Katherine Fifer (talk, edits)
- Valerie Lau (talk, edits)
- Matthew Meisel (talk, edits)
- Lewis Hahn (talk, edits)
- TA: Shawn Douglas (talk, edits)
Recent Changes
List of abbreviations:
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15 April 2024
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23:43 | User:Yanbin Huang 2 changes history +170 [Yanbin Huang (2×)] | |||
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23:43 (cur | prev) 0 Yanbin Huang talk contribs (→Granted Patents) | ||||
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23:43 (cur | prev) +170 Yanbin Huang talk contribs (→Granted Patents) | ||||
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22:11 | The paper that launched microfluidics - Xi Ning 14 changes history +9,705 [Xning098 (14×)] | |||
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22:11 (cur | prev) −6 Xning098 talk contribs (→Summary) | ||||
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21:44 (cur | prev) +688 Xning098 talk contribs (→Separation and quantification) | ||||
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21:45 | (Upload log) [Xning098 (4×)] | |||
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21:45 Xning098 talk contribs uploaded File:Figure 4 Tdesign.png | ||||
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21:30 Xning098 talk contribs uploaded File:Figure 3 Set-up3.png | ||||
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21:24 Xning098 talk contribs uploaded File:Figure 2 Set-up1.png | ||||
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21:09 Xning098 talk contribs uploaded File:Figure 1 electroosmotic flow.png | ||||
| 17:02 | CHEM-ENG590E:Wiki Textbook diffhist +54 Mredder talk contribs (→Chapter 7 - Fiber-based Microfluidics) | ||||
| m 07:22 | Paper Microfluidic Device for Archiving Breast Epithelial Cells diffhist +6 Sarah L. Perry talk contribs | ||||
| 06:39 | Hu diffhist +66 Hugangqing talk contribs | ||||
14 April 2024
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19:57 | Microfluidic Gradient Generators - Greg Schneider 6 changes history +919 [Nmhatre (6×)] | |||
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19:57 (cur | prev) +50 Nmhatre talk contribs (→Varying Flowrates and Asymmetrical Geometry) | ||||
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19:56 (cur | prev) −472 Nmhatre talk contribs (→Nonlinear Gradients) | ||||
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19:55 (cur | prev) +766 Nmhatre talk contribs (→Methods For Creating Non-linear Gradients) | ||||
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18:56 (cur | prev) +51 Nmhatre talk contribs (→Mathematical Model) | ||||
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18:56 (cur | prev) +51 Nmhatre talk contribs (→Induced Charge Electro-Osmosis (ICEO)) | ||||
