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Revision as of 19:20, 25 April 2007


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<html> <img src="http://openwetware.org/images/e/e2/Icon_info.png" alt="News" border="100"> </html>NEWS


<html> <img src="http://openwetware.org/images/b/b9/Icon_board.png" alt="Resources"> </html> PLANNING


<html> <img src="http://openwetware.org/images/e/e2/Icon_info.png" alt="News" border="0"> </html>WORKSHOP

<html> <img src="http://openwetware.org/images/b/b9/Icon_board.png" alt="Resources"> </html> PROJECT



<html> <img src="http://openwetware.org/images/e/e2/Icon_info.png"> </html> USEFUL LINKS

<html> <img src="http://openwetware.org/images/3/39/Icon_groups.png" alt="People"> </html>PEOPLE

Students


Advisors






Project Overview

  • Our goal is to design and implement molecular containers, which can be dynamically opened and closed by an external stimulus.
  • The containers will be implemented as DNA nanostructures, which afford a significant degree of positional control and chemical versatility.
  • As an initial proof-of-concept, we plan to use our DNA containers to demonstrate controllable activation ("delivery") of anti-thrombin aptamers.
  • We expect that molecular containers could have several interesting scientific and clinical applications, such as
    • Drug and gene delivery
    • Bio-marker scavenging (early detection of biomarkers)
    • Directed evolution (compartmentalized selections)
    • Using multiplexing for combinatorial chemical synthesis
    • Capture and stabilization of multiprotein complexes
    • Protein folding (chaperones)
    • Cell sorting

==Working Team Members== edit

Recent Changes

21 October 2017

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User:Dominique Brager/Notebook/481 Notebook/2017/09/20‎‎ (4 changes | history) . . (+395). . [Dominique Brager‎ (4×)]

     

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(cur | prev) . . (+11). . Dominique Brager (talk | contribs) (Description)

     

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     07:35 (Upload log) . . Dominique Brager (talk | contribs) uploaded File:GelElectrophoresis.jpg

20 October 2017

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Biomod/2017/StJohns:Results‎‎ (4 changes | history) . . (+60). . [Alexkk15‎ (4×)]

     

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     20:57 

(Upload log). .

[Alexkk15‎ (9×)]

     

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. . Alexkk15 (talk | contribs) uploaded File:Edited Image CC3 NClawX B S bind sybr June 22 2017-DNA Marker SYBR Gold.jpg

     

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     20:24  Sandbox‎ (diff | hist) . . (+5). . Alexkk15 (talk | contribs)

     19:26 

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Welcome to Harvard's 2006 iGEM team wiki! Please click on the project of interest for up to date information and current progress. Igem2006logo.gif




<html> <img src="http://openwetware.org/images/b/b9/Icon_board.png" alt="Resources"> </html>Planning


News and Announcements

Team

Projects

Project Planning

For visitors


<html> <img src="http://openwetware.org/images/e/e2/Icon_info.png" alt="News" border="0"> </html>In the Lab


Protocols

Lab Notebooks

Useful links

iGEM and OWW

Literature

Python

Miscellaneous

<html> <img src="http://openwetware.org/images/3/39/Icon_groups.png" alt="People"> </html>People


Super Heroes

DNA Nanostructures
Cyanobacteria
Cell surface targeting

Teaching Fellows

Advisors

Harvard 2006 iGem team.

Back row (L-R): Lewis, Katie, Tiffany, Valerie, Zhipeng, Matt.
Front row (L-R): Hetmann, Jeffrey, David, Perry.

And yes, that is the back end of a bronze rhinoceros.

.

A thanks goes to MIT's team page for our page formatting.