Difference between revisions of "User:Jungwhan Kim"

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*'''Ph.D. (2002 Sep -2006 Feb) : [http://pathology.jhu.edu/department/pathbio.cfm Johns Hopkins, School of Medicine (Pathobiology)], Maryland, USA (Mentor, [http://humangenetics.jhmi.edu/index.php?option=com_content&task=view&id=38&Itemid=51 Chi V. Dang, M.D., Ph.D.])'''
 
*'''Ph.D. (2002 Sep -2006 Feb) : [http://pathology.jhu.edu/department/pathbio.cfm Johns Hopkins, School of Medicine (Pathobiology)], Maryland, USA (Mentor, [http://humangenetics.jhmi.edu/index.php?option=com_content&task=view&id=38&Itemid=51 Chi V. Dang, M.D., Ph.D.])'''
 
*Post-Graduate Research; 2006 - 2007 ; Johns Hopkins University, School of Medicine, Maryland, USA. Dept. of Medicine (Supervisor; [http://humangenetics.jhmi.edu/index.php?option=com_content&task=view&id=38&Itemid=51 Chi V. Dang, M.D., Ph.D.])
 
*Post-Graduate Research; 2006 - 2007 ; Johns Hopkins University, School of Medicine, Maryland, USA. Dept. of Medicine (Supervisor; [http://humangenetics.jhmi.edu/index.php?option=com_content&task=view&id=38&Itemid=51 Chi V. Dang, M.D., Ph.D.])
*Post-Doctoral Fellow; 2007 - 2008 ; University of California San Francisco, School of Medicine, California, USA
+
*Post-Doctoral Fellow; 2007 - 2008 ; University of California San Francisco, School of Medicine, California, USA (Supervisor; Zena Werb, Ph.D.)
 
*'''Post-Doctoral Fellow; 2008 - present ; University of California San Diego, Division of Biological Sciences, California, USA (Supervisor; [http://www-biology.ucsd.edu/faculty/johnson.html Randall S. Johnson, Ph.D.])'''
 
*'''Post-Doctoral Fellow; 2008 - present ; University of California San Diego, Division of Biological Sciences, California, USA (Supervisor; [http://www-biology.ucsd.edu/faculty/johnson.html Randall S. Johnson, Ph.D.])'''
  

Revision as of 13:48, 28 January 2010

Go to JHIBRG

JHIBRG Member

JWKIM.jpg


Jungwhan Kim, D.V.M., Ph.D.

Post-Doctoral Fellow (Randall Johnson Lab)

Division of Biological Sciences

University of California, San Diego (UCSD)

9500 Gilman Drive NSB 5325A, La Jolla, CA 92093

Lab Tel) 858-822-5832

Email: vetjayk@gmail.com


Current Research Interests

  1. The role of stromal hypoxic responses in the development of breast cancer
  2. The role of hypoxia-inducible factors (HIFs) in adipogenesis


Previous Research Interests

  1. Cancer Metabolism; Oncogenic and hypoxic alterations of cellular metabolism by c-Myc and HIF-1.
  2. Metabolic reprogramming of cells by hypoxic induction of pyruvate dehydrogenase kinase 1 (PDK1).


Education and Professional Training


Academic Awards

  • Achievement Award for the 1st rank in The Veterinary National Board Examination, Korea (2000)
  • Dean’s Award for Academic Achievement, summa cum laude, Kon-kuk University, School of Veterinary Medicine, Seoul, Korea (2000)
  • Howard Hughes Medical Institute (HHMI), Pre-Doctoral Fellowship (2003 - 2006)
  • Pathology Young Investigators’ day Award, Excellence in Basic Research, Dept. of Pathology, Johns Hopkins, School of Medicine (2004)
  • Keystone Symposia Scholarship, Metabolomics: From Bioenergetics to Apoptosis (2006)
  • Susan G. Komen Foundation Post-Doctoral Fellowship (2008, Declined)


Publications (Link to Full Text)

Nature Reviews Cancer Cover Jan 2008
Cell Metabolism Cover Mar 2006
  1. Norihiko Takeda, Ellen L. O’Dea, Andrew Doedens, Jung-whan Kim, Alexander Weidmann, Christian Stockmann, Masataka Asagiri, M. Selete Simon, Alexander Hoffmann and Randall S. Johnson. Differential activation and antagonistic function of HIF-a isoforms in macrophages are essential for NO homeostasis. Genes and Development (2010), In press
  2. Jung-whan Kim and Randall S. Johnson. You Don't need a PHD to Grow a Tumor. Developmental Cell 16:781-2 (2009)
  3. Hosein Kouros-Mehr, Jung-whan Kim, Seth K. Bechis, and Zena Werb. GATA-3 and the Regulation of the Mammary Luminal Cell Fate. Current Opinion in Cell Biology 20:164-170 (2008)
  4. Chi V. Dang, Jung-whan Kim, Ping Gao, and Jason Yustein. The Interplay between MYC and HIF in Cancer. Nature Reviews Cancer 8:51-56 (2008)
  5. Jung-whan Kim, Ping Gao, Yen-Chun Liu, Gregg L. Semenza and Chi V. Dang. HIF-1 and dysregulated c-Myc cooperatively induce VEGF and metabolic switches, HK2 and PDK1. Mol. Cell. Biol. 27:7381-7393 (2007)
  6. Jung-whan Kim, Ping Gao, and Chi V. Dnag. Effects of hypoxia on tumor metabolism. Cancer and Metastasis Reviews. 26:291-8 (2007)
  7. Ryo Fukuda, Huafeng Zhang, Jung-whan Kim, Larissa Shimoda, Chi V. Dang, and Gregg L. Semenza. HIF-1 regulates cytochrome oxidase subunit composition to optimize the efficiency of respiration of hypoxic cells. Cell 129:111-122 (2007)
  8. Jung-whan Kim, and Chi V. Dang. Cancer's molecular sweet tooth and the Warburg effect. Cancer Research 66:8927-8930 (2006)
  9. Jung-whan Kim, Irina Tchernyshyov, Gregg L. Semenza, and Chi V. Dang. HIF-1-mediated expression of PDK: a metabolic switch required for cellular adaptation to hypoxia. Cell Metabolism, 3:177-185 (2006)
  10. Kathryn O'Donnell, Duonan Yu, Karen I. Zeller, Jung-whan Kim, Frederick Racke, Andrei Thomas-Tikhonenko and Chi V. Dang. Transferrin Receptor 1 is a direct Myc target gene required for cell cycle progression, Mol. Cell. Biol. 26:2373-2386 (2006)
  11. Rong Mao, Xiaowen Wang, Edward L. Spitznagel Jr., Laurence P. Frelin, Jason C. Ting, Huashi Ding, Jung-whan Kim, Ingo Ruczinski, Thomas J. Downey, and Jonathan Pevsner. Role of Gene Expression in the Developing Human Down Syndrome Brain and Heart. Genome Biology, 6:R107 (2005)
  12. Jung-whan Kim, Lawrence B. Gardner and Chi V. Dang. Oncogenic Alterations of Metabolism and the Warburg Effect. Drug Discovery Today: Disease Mechanisms, 2:233-235 (2005)
  13. Feng Li, Diane Wonsey, Young Ko, Kathryn O'Donnell, Karen I. Zeller, Jung-whan Kim, Jason Yustein, Linda A. Lee and Chi V. Dang. Myc stimulates mitochondrial biogenesis and nuclear encoded mitochondrial genes, Mol. Cell. Biol. 25: 6225-6234 (2005)
  14. Jung-whan Kim and Chi V. Dang. Multifaceted Roles of Glycolytic Enzymes. Trends in Biochemical Sciences, 30:142-150 (2005)
  15. Seung-Hoon Lee, Jung-whan Kim, Sun-Hee Oh, Yong-Jin Kim, Seung-Bae Rho, Kyungsook Park, Kui-Lea Park and Je-ho Lee. IFN-gamma/IRF-1-induced p27 down-regulates telomerase activity and human telomerase reverse transcriptase expression in human cervical cancer. FEBS Letters,579:1027-1033 (2005)
  16. Jung-whan Kim, Karen I. Zeller, Yunyue Wang, Anil G. Jegga, Bruce J. Aronow, Kathryn A. O'Donnell, and Chi V. Dang. Evaluation of Myc E-Box Phylogenetic Footprints in Glycolytic Genes by Chromatin Immunoprecipitation Assays. Mol. Cell. Biol. 24:5923-5936 (2004)
  17. Jung-whan Kim, Christopher W. Wong, Jeffery D. Goldsmith, C.Song, Weili Fu, Mary-Beth Allion, Meenhard Herlyn, Abu B. Al-Mehdi, and Ruth J. Muschel. Rapid apoptosis in the pulmonary vasculature distinguishes non-metastatic from metastatic melanoma cells. Cancer Letters, 213:203-212 (2004)
  18. Seung-Hoon Lee, Jung-whan Kim, Yongsuk Cho, Sunhee Oh, Hanwoong Lee, Wei Zhang and Jeho Lee. Interferon Regulatory Factor 1 (IRF-1) Is a Mediator for Interferon-g-induced Attenuation of Telomerase Activity and Human Telomerase Reverse Transcriptase (hTERT) Expression. Oncogene,22:381-391 (2003)
  19. Seung-Hoon Lee, Wei Zhang, Jung-joo Choi, Yong-Suk Cho, Sun-Hee Lee, Jung-whan Kim, Limei Hu, Jie Xu, Jinsong Liu and Joho Lee. Overexpression of the Thymosin beta-10 Gene in Human Ovarian Cancer Cells Disrupts F-Actin Stress Fiber and Leads to Apoptosis. Oncogene,20:6700-6706 (2001)
  20. Seung-Hoon Lee, Yong-Suk Cho, Chan-sub Shim, Jung-joo Choi, Sun-Hee Oh, Jung-whan Kim, Wei Zhang and Jeho Lee. Aberrant Expression of Smad4 Results in Resistance against the Growth Inhibitory Effect of Transforming Growth Factor-b (TGF-b) in the SiHa Human Cervical Carcinoma Cell Lines. Int. J. Cancer,94:500-507 (2001)

Book Chapters

  1. Chi V. Dang, Ping Gao and Jung-whan Kim. The Warburg effect and tumor metabolism. Encyclopedia of CANCER In press