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John Sy

Contact Information:

E-mail: (at), syjohn (at), syjohn (at)

MIT Fall 2006

Imperial iGEM

  • Imperial iGEM 2006 - Biological Oscillator based upon Predator-Prey interactions using quorum sensing molecules.



  • Sport – Swimming and Badminton
  • Travel – Travel over Europe, Asia, Africa, and North America
  • Arts – frequent concerts, plays, and musicals as well as enjoy visiting art galleries and reading classics

More Random Stuff About Me

  1. Favourite Colours: Orange & Blue
  2. Ethnic Origin: Chinese from the Philippines
  3. Place I would like to retire: somewhere in the USA
  4. Quote I like: "God grant me the serenity to accept the things I cannot change, to change the things I can, and the wisdom to know the difference"
  5. Religious Affiliation: None
  6. What I wanted to be when I grew up: pilot, businessman, lawyer, among other things
  7. What I want to do now: medicine
  8. Places I haven't been that I want to go: Australia & New Zealand
  9. My best place to relax: a remote island in the Philippines
  10. One thing I can't live without: internet...:)

20.310 Term Paper


Analysis of Human Immunodeficiency Virus Type I gp120 Receptor Interactions and its Implications on Future HIV Drug Therapy. (A single paper critique)


Prelimiarly Bibliography

  1. Chang MI, Panorchan P, Dobrowsky TM, Tseng Y, and Wirtz D. Single-molecule analysis of human immunodeficiency virus type 1 gp120-receptor interactions in living cells. J Virol. 2005 Dec;79(23):14748-55. DOI:10.1128/JVI.79.23.14748-14755.2005 | PubMed ID:16282475 | HubMed [Chang1]
  2. Doranz BJ, Baik SS, and Doms RW. Use of a gp120 binding assay to dissect the requirements and kinetics of human immunodeficiency virus fusion events. J Virol. 1999 Dec;73(12):10346-58. PubMed ID:10559353 | HubMed [Doranz99]
  3. Hill CM, Deng H, Unutmaz D, Kewalramani VN, Bastiani L, Gorny MK, Zolla-Pazner S, and Littman DR. Envelope glycoproteins from human immunodeficiency virus types 1 and 2 and simian immunodeficiency virus can use human CCR5 as a coreceptor for viral entry and make direct CD4-dependent interactions with this chemokine receptor. J Virol. 1997 Sep;71(9):6296-304. PubMed ID:9261346 | HubMed [Hill97]
  4. Kwong PD, Wyatt R, Robinson J, Sweet RW, Sodroski J, and Hendrickson WA. Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody. Nature. 1998 Jun 18;393(6686):648-59. DOI:10.1038/31405 | PubMed ID:9641677 | HubMed [Kwong98]
  5. Wu L, Gerard NP, Wyatt R, Choe H, Parolin C, Ruffing N, Borsetti A, Cardoso AA, Desjardin E, Newman W, Gerard C, and Sodroski J. CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5. Nature. 1996 Nov 14;384(6605):179-83. DOI:10.1038/384179a0 | PubMed ID:8906795 | HubMed [Wu96]
All Medline abstracts: PubMed | HubMed