User:Johnsy

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John Sy

Contact Information:

E-mail: john.sy (at) imperial.ac.uk, syjohn (at) gmail.com, syjohn (at) mit.edu

MIT Fall 2006

Imperial iGEM

  • Imperial iGEM 2006 - Biological Oscillator based upon Predator-Prey interactions using quorum sensing molecules.

Education

Interests

  • Sport – Swimming and Badminton
  • Travel – Travel over Europe, Asia, Africa, and North America
  • Arts – frequent concerts, plays, and musicals as well as enjoy visiting art galleries and reading classics

More Random Stuff About Me

  1. Favourite Colours: Orange & Blue
  2. Ethnic Origin: Chinese from the Philippines
  3. Place I would like to retire: somewhere in the USA
  4. Quote I like: "God grant me the serenity to accept the things I cannot change, to change the things I can, and the wisdom to know the difference"
  5. Religious Affiliation: None
  6. What I wanted to be when I grew up: pilot, businessman, lawyer, among other things
  7. What I want to do now: medicine
  8. Places I haven't been that I want to go: Australia & New Zealand
  9. My best place to relax: a remote island in the Philippines
  10. One thing I can't live without: internet...:)

20.310 Term Paper

TItle

Analysis of Human Immunodeficiency Virus Type I gp120 Receptor Interactions and its Implications on Future HIV Drug Therapy. (A single paper critique)

Abstract

Prelimiarly Bibliography

  1. Chang MI, Panorchan P, Dobrowsky TM, Tseng Y, and Wirtz D. Single-molecule analysis of human immunodeficiency virus type 1 gp120-receptor interactions in living cells. J Virol. 2005 Dec;79(23):14748-55. DOI:10.1128/JVI.79.23.14748-14755.2005 | PubMed ID:16282475 | HubMed [Chang1]
  2. Doranz BJ, Baik SS, and Doms RW. Use of a gp120 binding assay to dissect the requirements and kinetics of human immunodeficiency virus fusion events. J Virol. 1999 Dec;73(12):10346-58. DOI:10.1128/JVI.73.12.10346-10358.1999 | PubMed ID:10559353 | HubMed [Doranz99]
  3. Hill CM, Deng H, Unutmaz D, Kewalramani VN, Bastiani L, Gorny MK, Zolla-Pazner S, and Littman DR. Envelope glycoproteins from human immunodeficiency virus types 1 and 2 and simian immunodeficiency virus can use human CCR5 as a coreceptor for viral entry and make direct CD4-dependent interactions with this chemokine receptor. J Virol. 1997 Sep;71(9):6296-304. DOI:10.1128/JVI.71.9.6296-6304.1997 | PubMed ID:9261346 | HubMed [Hill97]
  4. Kwong PD, Wyatt R, Robinson J, Sweet RW, Sodroski J, and Hendrickson WA. Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody. Nature. 1998 Jun 18;393(6686):648-59. DOI:10.1038/31405 | PubMed ID:9641677 | HubMed [Kwong98]
  5. Wu L, Gerard NP, Wyatt R, Choe H, Parolin C, Ruffing N, Borsetti A, Cardoso AA, Desjardin E, Newman W, Gerard C, and Sodroski J. CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5. Nature. 1996 Nov 14;384(6605):179-83. DOI:10.1038/384179a0 | PubMed ID:8906795 | HubMed [Wu96]

All Medline abstracts: PubMed | HubMed