User:Ian Tay

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Revision as of 17:52, 22 February 2013 by Ian Tay (talk | contribs) (Current research)
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Contact Info

  • Ian Tay
  • MIT
  • Blg 16-760, Engelward Laboratory
  • iantayATmitDOTedu

Research interests

  1. DNA damage and repair
  2. Cellular responses to chemo-therapeutics
  3. Long non-coding RNA

Current research

I am working with Prof. Bevin Engelward and Dr. Scott Floyd at the Koch Institute to study how tumor cells respond to DNA damaging chemotherapeutic agents and genes that confer cellular resistance to those drugs.

Currently I am working on 2 projects:

1. To design a screen that will allow us to identify genes that can potentially affect cellular resistance to radiotherapy and chemotherapy via modulation of DNA damage and repair kinetics.

2. To study the effects of cell cycle on the evolution and resolution of DNA damage after chemotherapeutic agent treatment.

Previous projects

  • Development of a bioartificial hemodialysis device
  • Investigating pore formation in endothelial cells by mechanical stimulation
  • Non-coding RNAs in early neuronal differentiation