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Simulating evolution and then pooled sequencing
To do this we can use Dick Hudson's MS to lay down neutral variants (but the distribution really does not matter).
To do this we can use Kessner's Forqs. Forqs allows the user to specify the recombination rate file which might be useful in the future.
(1) draw a coverage from [math] Pois(\lambda) [/math] where [math] \lambda \approx 40-50 [/math]