Difference between revisions of "User:Etienne Robillard/Notebook/DFP"

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Reaction type: <font color=blue>oxidative desulfuration</font color> ([http://biocyc.org/META/NEW-IMAGE?type=COMPOUND&object=PARAOXON BioCyc])
Reaction type: <font color=blue>oxidative desulfuration</font color> ([http://biocyc.org/META/NEW-IMAGE?type=COMPOUND&object=PARAOXON BioCyc])
Related: [http://www.uniprot.org/uniprot/O15530 3-phosphoinositide-dependent protein kinase 1], [http://www.uniprot.org/uniprot/Q00005 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform]
== Safety ==
== Safety ==

Revision as of 09:19, 4 September 2013


Describe succinic acid here.

Use as voltage-gated pharmacochemical intermediates

  • (2R)-2-(methylamino)succinic acid (also known as N-methyl-D-asparte receptor) - A dicarboxilic acid usable as titrable buffer agent for orthogonal amino acid protection ?

Use as metal-bound electrolyte/proton conductor in cyclic imide additions (Maleimide)


French Press (123aa)


Enzyme name is acyl-coA synthase.

Pathway: http://www.kegg.jp/kegg-bin/show_pathway?T30165_04920+179507



doi: 10.1016/j.abb.2005.08.012, 10.1002/0471264180.or025.02

oph: A organo-phosphate (P-O) hydroxyl bound to a ketone or aldehyde. Synthetic intermediate and precursor to organo-phosphate agents known as AChE inhibitors. Reaction is catalyzed by the Organo-Phosphate Hydrolase enzyme, thus a ATP-dependent ligase.

dfp (Isoflurophate): http://www.drugbank.ca/drugs/DB00677, Wikipedia

EC (DFPase) http://www.genome.jp/dbget-bin/www_bget?ec:

EC (Parathion hydrolase) http://www.uniprot.org/uniprot/P0A433, http://www.drugbank.ca/drugs/DB02138


keywords: functionalized diphosphine, chim trills, DFP, Paraoxon

Reaction type: oxidative desulfuration (BioCyc)

Related: 3-phosphoinositide-dependent protein kinase 1, Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform


Unknown. The risks and effects of using succinic acid as calcium channel blocker may need further study.


  1. http://www.ccrc.uga.edu/~rcarlson/bcmb3100/Chap27.pdf
  2. http://www.ebi.ac.uk/interpro/entry/IPR000980
  3. Turning a protein kinase on or off from a single allosteric site via disulfide trapping


  1. Ogawa J, Soong CL, Honda M, and Shimizu S. Imidase, a dihydropyrimidinase-like enzyme involved in the metabolism of cyclic imides. Eur J Biochem. 1997 Jan 15;243(1-2):322-7. PubMed ID:9030755 | HubMed [imidase]

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