Difference between revisions of "User:Etienne Robillard/Notebook/Fmoc protected phenoxyalkylamine synthesis"

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(Microwave(light)-activated peptide synthesis under 2.45 GHz microwave frequency)
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* http://www.dddmag.com/articles/2011/08/microwave-peptide-synthesis
 
* http://www.dddmag.com/articles/2011/08/microwave-peptide-synthesis
 
* [http://host.madison.com/wsj/news/science/seely-on-science-chemical-agents-wage-war-against-bacteria/article_b5e25710-ed70-11e1-8e6b-0019bb2963f4.html Chemical agents wage war against owners of wireless communication devices operating in the 2.45 GHz spectrum]
 
* [http://host.madison.com/wsj/news/science/seely-on-science-chemical-agents-wage-war-against-bacteria/article_b5e25710-ed70-11e1-8e6b-0019bb2963f4.html Chemical agents wage war against owners of wireless communication devices operating in the 2.45 GHz spectrum]
* From gun control to wireless control, unregulation of the S-band frequency is not without risks of abuses from bioterrorists to develop dual-purposes, synthetic bioweapons: http://nanopatentsandinnovations.blogspot.se/2009/11/microwave-manufactures-semiconductor.html
+
* From gun control to wireless control, unregulation of the S-band frequency is not without risks of abuses from bioterrorists to develop dual-purposes, "smart" bioweapons: http://nanopatentsandinnovations.blogspot.se/2009/11/microwave-manufactures-semiconductor.html
 
** '''"The microwave reactor operates at 2.45 GHz and can be adapted to a continuous flow or autosampler system. "'''
 
** '''"The microwave reactor operates at 2.45 GHz and can be adapted to a continuous flow or autosampler system. "'''
  

Revision as of 17:21, 23 July 2013

The purpose of this page is to investigate the design and method of operation of novel psychotropic alkylamines and synthesis with Fmoc protected reagents, including primary and secondary amines as organocatalysts for development of synthetic pharmaceutical compounds with an aryl moeity, hence refered herein as N,N-substituted arylcyclohexylamines.

Microwave(light)-activated peptide synthesis under 2.45 GHz microwave frequency

Keywords

N-Methyl-d-aspartate receptor; PCP binding site; MK-801; Tetrahydroisoquinolines, AHL, NAND gate, Inverter, Artemisinin, 2.450, ghz, imine, dimer, tryptophane, PVOH, drug delivery, MIT, Boston Children Hospital, wireless, empathy, apathy, cognition, visual memory, learning, Dr. Robert S. Langer, MIT, Lanza, Holmes, mefloquine, Koch Institute, Viterbi algorithm

References

  1. Rodríguez H, Suarez M, and Albericio F. A convenient microwave-enhanced solid-phase synthesis of short chain N-methyl-rich peptides. J Pept Sci. 2010 Mar;16(3):136-40. DOI:10.1002/psc.1209 | PubMed ID:20127857 | HubMed [Rodriguez-H-2012]
  2. Ludwig M, Hoesl CE, Höfner G, and Wanner KT. Affinity of 1-aryl-1,2,3,4-tetrahydroisoquinoline derivatives to the ion channel binding site of the NMDA receptor complex. Eur J Med Chem. 2006 Aug;41(8):1003-10. DOI:10.1016/j.ejmech.2006.03.005 | PubMed ID:16675066 | HubMed [Ludwig-M-Cornelia-E-CE-Hoesl-Klaus-T-KT-Wanner]
All Medline abstracts: PubMed | HubMed

See also

  • Lewis Acid Catalysed Pictet Spengler Formation of Substituted 1,2,3,4-Tetrahydroisoquinolines.