Difference between revisions of "User:Etienne Robillard/Notebook/Fmoc protected phenoxyalkylamine synthesis"

From OpenWetWare
Jump to: navigation, search
(Microwave-activated peptide synthesis)
(Replacing page with '{{deleteme}}')
(8 intermediate revisions by the same user not shown)
Line 1: Line 1:
The purpose of this page is to investigate the design and method of operation of novel psychotropic
alkylamines and synthesis with Fmoc protected reagents, including primary and secondary amines
as organocatalysts for development of synthetic pharmaceutical compounds with an aryl moeity, hence
refered herein as N,N-substituted arylcyclohexylamines.
=== Microwave-activated peptide synthesis ===
* NB: the electromagnetic radio-frequency range most typical wireless devices operates under the FCC standard for communication devices is 2.4 ghz.
* In fact, most peoples are unaware this operating frequency can modulate Fmoc protected oligos by micro-wave thermal irradiation, thus a remote attacker may exploit this unregulated frequency range to trigger Fmoc-SPPS based orthogonal ligations of N-methyl rich peptides. [[http://www.faqs.org/patents/app/20100305182 1]]
* http://www.pharmainfo.net/reviews/new-era-field-synthetic-chemistry-microwave-assisted-synthesis
* http://www.dddmag.com/articles/2011/08/microwave-peptide-synthesis
* [http://host.madison.com/wsj/news/science/seely-on-science-chemical-agents-wage-war-against-bacteria/article_b5e25710-ed70-11e1-8e6b-0019bb2963f4.html Chemical agents wage war against owners of wireless communication devices operating in the 2.4ghz spectrum]
* From gun control to wireless control, unregulation of the S-band frequency is not without risks of abuses from bioterrorists to develop dual-purposes, synthetic bioweapons: http://nanopatentsandinnovations.blogspot.se/2009/11/microwave-manufactures-semiconductor.html
=== Keywords ===
N-Methyl-d-aspartate receptor; PCP binding site; MK-801; Tetrahydroisoquinolines, AHL,
=== References ===
#Rodriguez-H-2012 pmid=20127857
#Ludwig-M-Cornelia-E-CE-Hoesl-Klaus-T-KT-Wanner pmid=16675066
=== See also ===
* Lewis Acid Catalysed Pictet Spengler Formation of Substituted 1,2,3,4-Tetrahydroisoquinolines.

Latest revision as of 01:37, 30 April 2017

Crop.png It has been requested that this page be removed with restriction endonucleases.
Other articles for deletion are listed here.