User:Etienne Robillard/Notebook/Curcumin

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Curcumin: The Chuck Norris of methyltransferases by Etienne Robillard

Introduction

Curcuma longa (hence "curcumin") is a popular spice extract originating from India and used as an spicy additive in Indian gastronomy. The following outline present a summary of info on current research in alternative medicinal applications of the Curcuma longa plant.

Alzheimer

P53

Brain cancer

Breast cancer

Bibliography

  1. Lim GP, Chu T, Yang F, Beech W, Frautschy SA, and Cole GM. The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse. J Neurosci. 2001 Nov 1;21(21):8370-7. PubMed ID:11606625 | HubMed [alzheimer-2001]
  2. Xu Y, Ku B, Cui L, Li X, Barish PA, Foster TC, and Ogle WO. Curcumin reverses impaired hippocampal neurogenesis and increases serotonin receptor 1A mRNA and brain-derived neurotrophic factor expression in chronically stressed rats. Brain Res. 2007 Aug 8;1162:9-18. DOI:10.1016/j.brainres.2007.05.071 | PubMed ID:17617388 | HubMed [brain-2007]
  3. Senft C, Polacin M, Priester M, Seifert V, Kögel D, and Weissenberger J. The nontoxic natural compound Curcumin exerts anti-proliferative, anti-migratory, and anti-invasive properties against malignant gliomas. BMC Cancer. 2010 Sep 14;10:491. DOI:10.1186/1471-2407-10-491 | PubMed ID:20840775 | HubMed [brain-2010]
All Medline abstracts: PubMed | HubMed

See also

http://en.wikipedia.org/wiki/Curcumin