User:Tkadm30/Notebook/Arylcyclohexylamines/2013/05/24: Difference between revisions
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* CREB2: http://www.genome.jp/dbget-bin/www_bget?hsa:468 | * CREB2: http://www.genome.jp/dbget-bin/www_bget?hsa:468 | ||
* NMDAR1: http://www.kegg.jp/dbget-bin/www_bget?hsa:2902 | * NMDAR1: http://www.kegg.jp/dbget-bin/www_bget?hsa:2902 | ||
* You may want to view/download the uniprot dataset [http://www.uniprot.org/uniprot/P16220 here]. | |||
=== Notes === | === Notes === | ||
Revision as of 04:23, 27 May 2013
A jolie passage
.cell
- Calcium chloride (CaCl2) != potassium chloride [Ca2+]
- potassium chloride = food additive
- potassium chloride = KCl (anhydrous) [Cl-]
- KCl (-) mediated CREB1 gene expression: ($35.95)
- Keywords: CREB1, NMDA, potassium chloride, CaM kinase, striatal neurons, dizocilpine
NMDAR induced early-onset autistic spectrum (Alzheimer Disease)
- i found this paper worth the mention (2013): http://www.sciencedirect.com/science/article/pii/S0092867413002857 ($31.50)
- NMDA dependent cell adhesion (binding) notes
- c-fos: http://www.uniprot.org/uniprot/P01100
- CREB2: http://www.genome.jp/dbget-bin/www_bget?hsa:468
- NMDAR1: http://www.kegg.jp/dbget-bin/www_bget?hsa:2902
- You may want to view/download the uniprot dataset here.
Notes
- Désactivation sélective du récepteur NMDAR1 (Ser133?)
- Note: Ser133 ? (NMDAR1): un récepteur critique à la formation de la protéine beta-amyloid (APP) 4 d'après de récentes études à ce sujet. [2]
References
- Macías W, Carlson R, Rajadhyaksha A, Barczak A, and Konradi C. Potassium chloride depolarization mediates CREB phosphorylation in striatal neurons in an NMDA receptor-dependent manner. Brain Res. 2001 Feb 2;890(2):222-32. DOI:10.1016/s0006-8993(00)03163-2 |
- De Cesare D, Jacquot S, Hanauer A, and Sassone-Corsi P. Rsk-2 activity is necessary for epidermal growth factor-induced phosphorylation of CREB protein and transcription of c-fos gene. Proc Natl Acad Sci U S A. 1998 Oct 13;95(21):12202-7. DOI:10.1073/pnas.95.21.12202 |
- Du K and Montminy M. CREB is a regulatory target for the protein kinase Akt/PKB. J Biol Chem. 1998 Dec 4;273(49):32377-9. DOI:10.1074/jbc.273.49.32377 |
- Matthews RP, Guthrie CR, Wailes LM, Zhao X, Means AR, and McKnight GS. Calcium/calmodulin-dependent protein kinase types II and IV differentially regulate CREB-dependent gene expression. Mol Cell Biol. 1994 Sep;14(9):6107-16. DOI:10.1128/mcb.14.9.6107-6116.1994 |
- Lee HJ, Mignacca RC, and Sakamoto KM. Transcriptional activation of egr-1 by granulocyte-macrophage colony-stimulating factor but not interleukin 3 requires phosphorylation of cAMP response element-binding protein (CREB) on serine 133. J Biol Chem. 1995 Jul 7;270(27):15979-83. DOI:10.1074/jbc.270.27.15979 |
