Difference between revisions of "User:Dileep D. Monie"

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==Contact Info==
 
==Contact Info==
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[[Image:OWWEmblem.png|thumb|right|Dileep D. Monie (an artistic interpretation)]]
 
[[Image:OWWEmblem.png|thumb|right|Dileep D. Monie (an artistic interpretation)]]
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*Dileep D. Monie
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*Dileep Monie
*Johns Hopkins University
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*Immunologist | Bioengineer | Entrepreneur
 
*Baltimore, MD, USA  
 
*Baltimore, MD, USA  
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*[http://www.linkedin.com/in/dmonie Connect with me on LinkedIn]
 
*[[Special:Emailuser/Dileep D. Monie|Email me through OpenWetWare]]
 
*[[Special:Emailuser/Dileep D. Monie|Email me through OpenWetWare]]
  
I work in the [http://www.hopkinsmedicine.org/som/ School of Medicine] at [http://www.jhu.edu/ JHU].  I learned about [[OpenWetWare]] from the [http://events.ccc.de/congress/2007/Fahrplan/events/2329.en.html 24C3 Endy lecture], and I've joined because I am interested in contributing to the [[The_BioBricks_Foundation:Standards/Technical|BBF Technical Standards]].
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I learned about [[OpenWetWare]] from the [http://events.ccc.de/congress/2007/Fahrplan/events/2329.en.html 24C3 Endy lecture], and I've joined because I am interested in contributing to the [[The_BioBricks_Foundation:Standards/Technical|BBF Technical Standards]].
  
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==Research Interests==
 
==Research Interests==
# Basic Synthetic Biology
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# Synthetic Biology
## Epigenetics - Manipulating chromatin structures (such as those regulated by DNA methylation and histone tail modifications) as a form of wetware programming
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## [[The_BioBricks_Foundation:Standards/Technical|Standards]] - Establishing standards for biological parts to ensure interoperability and allow for construction of complex systems
## Biocircuits - Designing devices and chassis for cellular computation and communications
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## Biocircuits - Implementing wetware abstraction layers to allow creation of devices for cellular computation and communications
## Virology - Engineering viruses and pseudoviruses to deliver biological parts and initiate or disrupt signal transduction
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## Epigenetics - Manipulating chromatin structures with histone and DNA modifications as a form of biological software programming
# Applied Synthetic Biology
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## Delivery Systems - Making viruses or other vectors for targeted delivery of DNA parts into an established host genome
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# Bioengineering
 
## Immunology - Defining the theoretical framework and designing components for an artificial immune system
 
## Immunology - Defining the theoretical framework and designing components for an artificial immune system
## Astrobiology - Engineering sensory devices and energy pathways for extreme environments
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## Drug Discovery - Designing cell reporter systems to detect biomolecule interactions and perturbations in signal transduction
## Biocomputing - Exploring silicon-based hardware-wetware communications interface
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## Astrobiology - Engineering energy pathways and lifeforms sustainable in extreme environments
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## Biocomputing - Integrating logic biocircuits on a very large scale in single cell and multicellular systems
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# Biosecurity and Biosafety
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## Policy - Balancing the needs of an open hacker community with access restrictions
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## Testing and Certification - Establishing an "Underwriters Laboratories" for developing standards and test procedures for biosafety
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## Countermeasures - Designing fail-safe mechanisms to mitigate potential synthetic biology abuses
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==BBF Contributions==
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* [[/Notebook/BBF_Standards_Measurement|Promoter Measurement Test]]
  
==Current Projects==
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==OWW Brain Dump==
*[[The_BioBricks_Foundation:Standards/Technical/Measurement|Promoter Measurement Test]]
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*[[/Notebook|Notebook]]
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*[[/Recipes|Recipes]]
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*[http://openwetware.org/index.php?title=Special%3ALog&type=upload&user=Dileep+D.+Monie Upload log]
  
My wet lab contributions are documented in my [[User:Dileep_D._Monie/Notebook|OWW Notebook]].
 
 
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==Publications==
 
==Publications==
Replace the PubMed ID's ("pmid=#######") below with the PubMed ID's for your publications.  You can add or remove lines as needed
 
 
<biblio>
 
<biblio>
#Paper1 pmid=6947258
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#Paper1 pmid=10201994
#Paper2 pmid=13718526
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#Paper2 pmid=10441117
// leave a comment about a paper here
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#Paper3 pmid=19298678
#Book1 isbn=0879697164
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#Paper4 pmid=21212284
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#Book1 isbn=9780781764964
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// Contributed section on "Pulmonary Hypertension" (pp. 148-9)
 
</biblio>
 
</biblio>
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Revision as of 07:06, 23 January 2013

Contact Info

I learned about OpenWetWare from the 24C3 Endy lecture, and I've joined because I am interested in contributing to the BBF Technical Standards.

BBF Contributions

OWW Brain Dump

Publications

  1. Monday SR, Vath GM, Ferens WA, Deobald C, Rago JV, Gahr PJ, Monie DD, Iandolo JJ, Chapes SK, Davis WC, Ohlendorf DH, Schlievert PM, and Bohach GA. Unique superantigen activity of staphylococcal exfoliative toxins. J Immunol. 1999 Apr 15;162(8):4550-9. PubMed ID:10201994 | HubMed [Paper1]
  2. Vath GM, Earhart CA, Monie DD, Iandolo JJ, Schlievert PM, and Ohlendorf DH. The crystal structure of exfoliative toxin B: a superantigen with enzymatic activity. Biochemistry. 1999 Aug 10;38(32):10239-46. DOI:10.1021/bi990721e | PubMed ID:10441117 | HubMed [Paper2]
  3. Kelly JR, Rubin AJ, Davis JH, Ajo-Franklin CM, Cumbers J, Czar MJ, de Mora K, Glieberman AL, Monie DD, and Endy D. Measuring the activity of BioBrick promoters using an in vivo reference standard. J Biol Eng. 2009 Mar 20;3:4. DOI:10.1186/1754-1611-3-4 | PubMed ID:19298678 | HubMed [Paper3]
  4. Oh U, McCormick MJ, Datta D, Turner RV, Bobb K, Monie DD, Sliskovic DR, Tanaka Y, Zhang J, Meshulam J, and Jacobson S. Inhibition of immune activation by a novel nuclear factor-kappa B inhibitor in HTLV-I-associated neurologic disease. Blood. 2011 Mar 24;117(12):3363-9. DOI:10.1182/blood-2010-10-306571 | PubMed ID:21212284 | HubMed [Paper4]
  5. Rajnish Prasad, editor-in-chief; Scott Kahan, editor-in-chief; Pankaj Mohan, associate editor. In a page. Philadelphia: Lippincott Williams & Wilkins, 2007. ISBN:9780781764964 [Book1]
    Contributed section on "Pulmonary Hypertension" (pp. 148-9)
All Medline abstracts: PubMed | HubMed