My research concerns using engineered RNA as adaptive gene regulatory elements. These RNAs are able to detect changes in the cellular environment, e.g., cancerous or benign, and act in response to that information, e.g., lead the cell to kill itself or do nothing. I'm currently designing and testing RNA molecules to efficiently knock down genes in cancerous cells but not in normal cells. In addition, I'm extending existing RNA regulatory platforms to be responsive to new signals, or to respond to signals with improved dynamics.
<html> <a href="http://clustrmaps.com/counter/maps.php?url=http://openwetware.org/wiki/User:Despaux" id="clustrMapsLink"><img src="http://clustrmaps.com/counter/index2.php?url=http://openwetware.org/wiki/User:Despaux" border=1 alt="Locations of visitors to this page"onError="this.onError=null; this.src='http://www.meetomatic.com/images/clustrmaps-back-soon.jpg'; document.getElementById('clustrMapsLink').href='http://clustrmaps.com/'"> </a> </html>