User:David Gresham

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Contact Info

David Gresham
  • David Gresham
  • New York University
  • 100 Washington Square East
  • 1009 Silver
  • New York, NY, 10003, USA.
  • Ph: 212-998-3879
  • Fax: 212-995-4015
  • Email: dgresham AT
  • Email me through OpenWetWare
  • Visit lab wiki here


  • 2004-2009, Post-doctoral researcher, Botstein Laboratory, Princeton, NJ
  • 2001, PhD, Edith Cowan University, Perth, Australia
  • 1997, BSc, McGill University, Montreal, Canada

from 2001-2004 I worked as a Research Editor for the journal, Nature Genetics

Research interests

  1. Cellular growth regulation
  2. Molecular basis of adaptive evolution
  3. Post-transcriptional gene regulation


  1. Ho CH, Magtanong L, Barker SL, Gresham D, Nishimura S, Natarajan P, Koh JLY, Porter J, Gray CA, Andersen RJ, Giaever G, Nislow C, Andrews B, Botstein D, Graham TR, Yoshida M, and Boone C. A molecular barcoded yeast ORF library enables mode-of-action analysis of bioactive compounds. Nat Biotechnol. 2009 Apr;27(4):369-77. DOI:10.1038/nbt.1534 | PubMed ID:19349972 | HubMed [Paper1]
  2. Airoldi EM, Huttenhower C, Gresham D, Lu C, Caudy AA, Dunham MJ, Broach JR, Botstein D, and Troyanskaya OG. Predicting cellular growth from gene expression signatures. PLoS Comput Biol. 2009 Jan;5(1):e1000257. DOI:10.1371/journal.pcbi.1000257 | PubMed ID:19119411 | HubMed [Paper2]
  3. Gresham D, Desai MM, Tucker CM, Jenq HT, Pai DA, Ward A, DeSevo CG, Botstein D, and Dunham MJ. The repertoire and dynamics of evolutionary adaptations to controlled nutrient-limited environments in yeast. PLoS Genet. 2008 Dec;4(12):e1000303. DOI:10.1371/journal.pgen.1000303 | PubMed ID:19079573 | HubMed [Paper3]
  4. Gresham D and Kruglyak L. Rise of the machines. PLoS Genet. 2008 Aug 1;4(8):e1000134. DOI:10.1371/journal.pgen.1000134 | PubMed ID:18670625 | HubMed [Paper4]
  5. Gresham D, Dunham MJ, and Botstein D. Comparing whole genomes using DNA microarrays. Nat Rev Genet. 2008 Apr;9(4):291-302. DOI:10.1038/nrg2335 | PubMed ID:18347592 | HubMed [Paper5]
  6. Brauer MJ, Huttenhower C, Airoldi EM, Rosenstein R, Matese JC, Gresham D, Boer VM, Troyanskaya OG, and Botstein D. Coordination of growth rate, cell cycle, stress response, and metabolic activity in yeast. Mol Biol Cell. 2008 Jan;19(1):352-67. DOI:10.1091/mbc.E07-08-0779 | PubMed ID:17959824 | HubMed [Paper6]
  7. Schacherer J, Ruderfer DM, Gresham D, Dolinski K, Botstein D, and Kruglyak L. Genome-wide analysis of nucleotide-level variation in commonly used Saccharomyces cerevisiae strains. PLoS One. 2007 Mar 28;2(3):e322. DOI:10.1371/journal.pone.0000322 | PubMed ID:17389913 | HubMed [Paper7]
  8. Gabriel A, Dapprich J, Kunkel M, Gresham D, Pratt SC, and Dunham MJ. Global mapping of transposon location. PLoS Genet. 2006 Dec 15;2(12):e212. DOI:10.1371/journal.pgen.0020212 | PubMed ID:17173485 | HubMed [Paper8]
  9. Heck JA, Gresham D, Botstein D, and Alani E. Accumulation of recessive lethal mutations in Saccharomyces cerevisiae mlh1 mismatch repair mutants is not associated with gross chromosomal rearrangements. Genetics. 2006 Sep;174(1):519-23. DOI:10.1534/genetics.106.059311 | PubMed ID:16816424 | HubMed [Paper9]
  10. Gresham D, Ruderfer DM, Pratt SC, Schacherer J, Dunham MJ, Botstein D, and Kruglyak L. Genome-wide detection of polymorphisms at nucleotide resolution with a single DNA microarray. Science. 2006 Mar 31;311(5769):1932-6. DOI:10.1126/science.1123726 | PubMed ID:16527929 | HubMed [Paper10]
  11. Morar B, Gresham D, Angelicheva D, Tournev I, Gooding R, Guergueltcheva V, Schmidt C, Abicht A, Lochmuller H, Tordai A, Kalmar L, Nagy M, Karcagi V, Jeanpierre M, Herczegfalvi A, Beeson D, Venkataraman V, Warwick Carter K, Reeve J, de Pablo R, Kucinskas V, and Kalaydjieva L. Mutation history of the roma/gypsies. Am J Hum Genet. 2004 Oct;75(4):596-609. DOI:10.1086/424759 | PubMed ID:15322984 | HubMed [Paper11]
  12. Zhivotovsky LA, Underhill PA, Cinnioğlu C, Kayser M, Morar B, Kivisild T, Scozzari R, Cruciani F, Destro-Bisol G, Spedini G, Chambers GK, Herrera RJ, Yong KK, Gresham D, Tournev I, Feldman MW, and Kalaydjieva L. The effective mutation rate at Y chromosome short tandem repeats, with application to human population-divergence time. Am J Hum Genet. 2004 Jan;74(1):50-61. DOI:10.1086/380911 | PubMed ID:14691732 | HubMed [Paper12]
  13. Gresham D. Reversing Babel with GO. Nat Genet. 2002 Jul;31(3):230. DOI:10.1038/ng0702-230 | PubMed ID:12089515 | HubMed [Paper13]
  14. Gresham D, Morar B, Underhill PA, Passarino G, Lin AA, Wise C, Angelicheva D, Calafell F, Oefner PJ, Shen P, Tournev I, de Pablo R, Kuĉinskas V, Perez-Lezaun A, Marushiakova E, Popov V, and Kalaydjieva L. Origins and divergence of the Roma (gypsies). Am J Hum Genet. 2001 Dec;69(6):1314-31. DOI:10.1086/324681 | PubMed ID:11704928 | HubMed [Paper14]
  15. Kalaydjieva L, Gresham D, and Calafell F. Genetic studies of the Roma (Gypsies): a review. BMC Med Genet. 2001;2:5. PubMed ID:11299048 | HubMed [Paper15]
  16. Chandler D, Angelicheva D, Heather L, Gooding R, Gresham D, Yanakiev P, de Jonge R, Baas F, Dye D, Karagyozov L, Savov A, Blechschmidt K, Keats B, Thomas PK, King RH, Starr A, Nikolova A, Colomer J, Ishpekova B, Tournev I, Urtizberea JA, Merlini L, Butinar D, Chabrol B, Voit T, Baethmann M, Nedkova V, Corches A, and Kalaydjieva L. Hereditary motor and sensory neuropathy--Lom (HMSNL): refined genetic mapping in Romani (Gypsy) families from several European countries. Neuromuscul Disord. 2000 Dec;10(8):584-91. PubMed ID:11053686 | HubMed [Paper16]
  17. Kalaydjieva L, Gresham D, Gooding R, Heather L, Baas F, de Jonge R, Blechschmidt K, Angelicheva D, Chandler D, Worsley P, Rosenthal A, King RH, and Thomas PK. N-myc downstream-regulated gene 1 is mutated in hereditary motor and sensory neuropathy-Lom. Am J Hum Genet. 2000 Jul;67(1):47-58. DOI:10.1086/302978 | PubMed ID:10831399 | HubMed [Paper17]

All Medline abstracts: PubMed | HubMed

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