User:Carsten C. Mahrenholz

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Revision as of 03:31, 6 November 2008 by Carsten C. Mahrenholz (talk | contribs) (Research interests)
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I am a new member of OpenWetWare!

Contact Info

Carsten C. Mahrenholz (an artistic interpretation)
  • Carsten C. Mahrenholz
  • Molecular Libraries and Recognition Group
  • Charité Medical School

I work in the Institute of Medical Immunology at Charité Medical School. I've joined because Hopefully I can find some people to share information about my phd-topics (coiled-coils and SPOT-synthesis) and add some related methodical and input value.

Education

  • since 2005, PhD student (Boichemistry)
             Institute of Medical Immunology, Charité Medical School, Berlin
  • 2001-2005, Dipl. Biol. (Molecular Biology, Biophysics, Immunology)
             Humboldt University, Berlin and Gutenberg University, Mainz
  • 2006-2008, MBA (General Management - Dual Award)
             Berlin School of Economics and Ashcroft International Business School, Cambridge

Research interests

  1. Coiled-Coil interaction, stoichometry and peptide design
 We use biochemical high-throughput(SPOT- and Peptide-Synthesis) methods, 
        biophysics (ITC, AUZ, Biacore) and 
        informatics (SVM)
 to define the rules of association on the amino-acid level.
  1. association landscapes for protein interaction
  2. evolution theory

Publications

  1. Goldbeter A and Koshland DE Jr. An amplified sensitivity arising from covalent modification in biological systems. Proc Natl Acad Sci U S A. 1981 Nov;78(11):6840-4. PubMed ID:6947258 | HubMed [Paper1]
  2. JACOB F and MONOD J. Genetic regulatory mechanisms in the synthesis of proteins. J Mol Biol. 1961 Jun;3:318-56. PubMed ID:13718526 | HubMed [Paper2]
    leave a comment about a paper here
  3. Mark Ptashne. A genetic switch. Cold Spring Harbor, N.Y.: Cold Spring Harbor Laboratory Press, 2004. ISBN:0879697164 [Book1]
All Medline abstracts: PubMed | HubMed

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