Difference between revisions of "Tamoxifen administration to mice"

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== See also ==
== See also ==
* [http://en.wikipedia.org/wiki/Tamoxifen Tamoxifen in Wikipedia]

Revision as of 04:12, 26 April 2007

One of the uses of tamoxifen in the lab is the activation of enzymes deactivated via an estrogen-binding domain, like Cre-ER (Cre-LBD). Tamoxifen is an estrogen analogue that binds with higher affinity than estrogen to altered estrogen binding domains.

Tamoxifen is administered to mice in 2 main ways: via the drinking water or in an oily mix given via a feeding needle. Administration via the drinking water is easier but somewhat less reliable.

Chemical data for tamoxifen

Tamoxifen administration via the drinking water

Tamoxifen administration via a feeding needle

See also