Difference between revisions of "Tamoxifen administration to mice"

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Tamoxifen is administered to mice in 2 main ways: via the drinking water or in an oily mix given via a feeding needle. Administration via the drinking water is easier but somewhat less reliable.
 
Tamoxifen is administered to mice in 2 main ways: via the drinking water or in an oily mix given via a feeding needle. Administration via the drinking water is easier but somewhat less reliable.
  
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== Chemical data for tamoxifen ==
  
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== Tamoxifen administration via the drinking water ==
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== Tamoxifen administration via a feeding needle ==
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== See also ==
 
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Revision as of 03:11, 26 April 2007

One of the uses of tamoxifen in the lab is the activation of enzymes deactivated via an estrogen-binding domain, like Cre-ER (Cre-LBD). Tamoxifen is an estrogen analogue that binds with higher affinity than estrogen to altered estrogen binding domains.

Tamoxifen is administered to mice in 2 main ways: via the drinking water or in an oily mix given via a feeding needle. Administration via the drinking water is easier but somewhat less reliable.

Chemical data for tamoxifen

Tamoxifen administration via the drinking water

Tamoxifen administration via a feeding needle

See also