Talk:CH391L/S2013 Tanya Raymond Jan 23 2013: Difference between revisions

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(New page: *'''Logan Myler''' In the model that the authors propose, CtIP and Exo1 are responsible for parallel pathways to initially resect back the DNA, and this is followe...)
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Revision as of 14:53, 29 January 2013

  • Logan Myler In the model that the authors propose, CtIP and Exo1 are responsible for parallel pathways to initially resect back the DNA, and this is followed by a phosphorylation-dependent loading of DNA2 and CtIP for further resection. However, in the absence of CtIP, there is still RPA loading onto chromatin, and in the absence of DNA2, RPA loading is almost completely abrogated. Isn't this contradictory to the model?