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Publications 2019 D.García-Morales, T. Navarro, A. Iannini, P.S. Pereira, D.G. Míguez*, F. Casares*, Dynamic Hh signalling can generate temporal information during tissue patterning, Development 146, dev176933 (2019) (*corresponding authors) A. Núñez, G. Amo de Paz, A. Rastrojo, Z. Ferencova, A.M Gutiérrez-Bustillo, A. Alcamí, D. A. Moreno*, R. Guantes* Temporal patterns of variability for prokaryotic and eukaryotic diversity in the urban air of Madrid (Spain). Atmospheric Environment (2019) 217, 11697 (*corresponding authors) 2018 S. Márquez-Jurado, J. Díaz-Colunga, R. Pires das Neves, A. Martínez-Lorente, F. Almazán, R. Guantes* and F.J. Iborra*, Mitochondrial levels determine variability in cell death by modulating apoptotic gene expression, Nature Communications 9, 389 (2018) (*corresponding authors). V. Doldán-Martelli and D.G. Míguez, Drug treatment efficiency depends on the initial state of activation in nonlinear pathways, Scientific Reports 8, 1-10 (2018). A.F. Lima, G. May, J. Díaz-Colunga, S. Pedreiro, A. Paiva, L. Ferreira, T. Enver, F. J. Iborra and R. Pires das Neves, Osmotic modulation of chromatin impacts on efficiency and kinetics of cell fate modulation, Scientific Reports 8,7210 (2018). L. Marcos-Villar, J. Díaz-Colunga, J. Sandoval, N. Zamarreño, S. Landeras-Bueno, M. Esteller, A. Falcón and A. Nieto, Epigenetic control of influenza virus: role of H3K79 methylation in interferon-induced antiviral response, Scientific Reports 8, 1230(2018). 2017 A. Aires, J. Fernández-Cadenas, R. Guantes* and A. L. Cortajarena*, An experimental and computational framework for engineering multifunctional nanoparticles: designing selective anticancer therapies, Nanoscale (2017) 9, 13760-1377 (*corresponding authors). A. Núñez, G. Amo de Paz, Z. Ferencova, A. Rastrojo,R. Guantes, A. M. García, A. Alcamí, A.M Gutiérrez-Bustillo, D. A. Moreno, Validation of the Hirst-type spore trap for simultaneous monitoring of prokaryotic and eukaryotic diversity in urban air samples by NGS. Appl. Environ. Microbiol. (2017) 83:13, e00472-17. F. Eduati, V. Doldán-Martelli, B. Klinger, T. Cokelaer, A. Sieber, F. Kogera, M. Dorel, M.J. Garnett, N. Blüthgen and J. Saez-Rodriguez Drug Resistance Mechanisms in Colorectal Cancer Dissected with Cell Type–Specific Dynamic Logic Models, Cancer Research (2017) 77:12, 3364. 2016 M. Bernabé-Rubio, G. Andrés, J. Casares-Arias, J. Fernández-Barrera, L. Rangel, N. Reglero-Real, D.C. Gershlick, J.J. Fernández, J. Millán, I. Correas, D.G. Miguez, M.A. Alonso, Novel role for the midbody in primary ciliogenesis by polarized epithelial cells, J. Cell Biology 214, 259–273 (2016) A. Valencia-Expósito*, I. Grosheva*, D. G. Míguez*, A. González-Reyes, M. D. Martín-Bermudo, The Myosin Light Chain Phosphatase is required in epithelial cells to control basal actomyosin oscillations governing tissue elongation, Nature Communications 7, 10746 (2016) (*shared 1st authorship) J. Estrada, N. Andrew, D. Gibson, F. Chang, Florian Gnad and J. Gunawardena, Cellular Interrogation: Exploiting Cell-to-Cell Variability to Discriminate Regulatory Mechanisms in Oscillatory Signalling. PLoS Computational Biology 12, e1004995 (2016). R. Guantes, I. Benedetti, R. Silva-Rocha and V. de Lorenzo, Transcription factor levels enable metabolic diversification of single cells of environmental bacteria, The ISME Journal (2016) R. Guantes, J. Díaz-Colunga and F. J. Iborra, Mitochondria and the non-genetic origins of cell-to-cell variability: More is different, BioEssays 38, 64-76 (2016). 2015 D. G. Míguez, A Branching Process to Characterize the Dynamics of Stem Cell Differentiation, Scientific Reports 5, 13265 (2015) R. Guantes, A. Rastrojo, R. Neves, A. Lima, B. Aguado and F. J. Iborra, Global variability in gene expression and alternative splicing is modulated by mitochondrial content, Genome Research 25(5), 633-644 (2015). R. Guantes, S. Arganda and G. G. de Polavieja, Biophysics of Adaptation in a Computational Model of the Leech T Neuron, in Jaeger D, Jung R (Eds.) Encyclopedia of Computational Neuroscience (2015). V. Doldán-Martelli, D. G. Míguez, Synergistic Interaction between Selective Drugs in Cell Populations Models, PloS one 10 (2), e0117558 (2015). 2014 S. H. Mejías, B. Sot, R. Guantes and A. L. Cortajarena , Controlled nanometric fibers of self-assembled designed protein scaffolds, Nanoscale 6, 10982-10988 (2014). J. Aguirre, D. Bajic and R. Guantes, Biología de Sistemas, in Sebastián A, Pascual-García A (Eds.), Bioinformática con Ñ (2014)ISBN: 978-84-617-1976-X (free textbook on bioinformatics, in Spanish). Downloadable from Scribd. A. L. Sanz & D. G. Míguez, Dual R-Smads interplay in the regulation of vertebrate neurogenesis. Neurogenesis 1, e29529 (2014). 2013 T. Ruiz-Herrero, J. Estrada, R. Guantes, D. G. Miguez, A tunable coarse-grained model for ligand-receptor interaction, PLOS Computational Biology 9, e1003274 (2013). D. G. Míguez*, E. Gil-Guiñón, S. Pons and E. Martí Smad2 and Smad3 cooperate and antagonize simultaneously in vertebrate neurogenesis, Journal Of Cell Science 126, 5335 (2013). (*First and corresponding authorship) M. Saade, I. Gutiérrez-Vallejo, G. Le Dréau, M. A. Rabadán, D. G. Miguez, J. Buceta, E. Martí Sonic hedgehog signaling switches the mode of division in the developing nervous system, Cell Reports 4,492 (2013). D. G. Míguez, Network Nonlinearities in Drug Treatment, Interdisciplinary Sciences: Computational Life Sciences 5,85 (2013). P. Gregorio-Godoy, D. G. Míguez, Synthetic approaches to study transcriptional networks and noise in mammalian systems, IET Systems Biology 7,11 (2013). V. Doldán-Martelli, R. Guantes, D. G. Míguez, A Mathematical Model for the Rational Design of Chimeric Ligands in Selective Drug Therapies, CPT: Pharmacometrics & Systems Pharmacology 2, e26 (2013). J. Estrada and R. Guantes, Dynamic and structural constraints in signal propagation by regulatory networks Mol. BioSyst. 9, 268-284 (2013). 2012 R. Guantes, B. Cayrol, F. Busi and V. Arluison, Positive Regulatory Dynamics by a small noncoding RNA: Speeding Up Responses Under Temperature Stress, Molecular Biosystems 8 , 1707-1715 (2012). Florian Gnad , Javier Estrada and Jeremy Gunawardena ,Proteus: a web-based, context-specific modelling tool for molecular network, Bioinformatics 28, 1284 - 1286 (2012). V. Doldán-Martelli, D. G. Míguez, Theoretical Approaches to Growth Hormone Signaling, in 'Growth Hormones: Synthesis, Regulation and Health Implications', Eds. A. Andersdtr and J. Anderssen Nova Publishers ISBN 978-1-61942-681-8 (2012). 2011 D. G. Míguez, Milos Dolnik, Irving Epstein and Alberto P. Muñuzuri, Interaction Of Chemical Patterns in Coupled Layers, Phys. Rev. E, 84, 046210 (2011). 2010 D. G. Míguez, The role of asymmetric binding in ligand-receptor systems with 1:2 interaction ratio Biophys Chem 148, 74-81 (2010) D.G. Míguez, "Forcing of Nonlinear Pattern Formation Systems", Lambert Academic Publishing, ISBN 9783838364223 (2010) Book R. Guantes, J. Estrada and J. F. Poyatos,Trade-offs and noise tolerance in signal detection by genetic circuits, PLoS ONE 5, e12314 (2010) 2009 D. G. Míguez, P. McGraw, A. P. Muñuzuri and M. Menzinger, Selection of Flow-Distributed Oscillation and Turing Patterns by Boundary Forcing in a Linearly Growing, Oscillating Medium, Phys. Rev. E, 80, 026208 (2009). 2008 I. A. Swinburne, D. G. Míguez, D. Landgraf, and P. A. Silver, Intron length increases oscillatory periods of gene expression in animal cells, Genes & Dev., 22 2008, 2342-2346 (2008). S. Alonso, D. G. Míguez, F. Sagués, Differential susceptibility to noise of mixed Turing and Hopf modes in a photosensitive chemical medium, Europhys. Lett, 81, 30006 (2008). R. Guantes and J. F. Poyatos,Multistable decision switches for flexible control of epigenetic differentiation, PLoS Computational Biology 4, e1000235 (2008) 2007 D. G. Míguez, V. K. Vanag, I. R. Epstein, Fronts and pulses in an enzymatic reaction with glucose oxidase P.N.A.S. 104, 6992 (2007). S. Arganda, R. Guantes and G. G. de Polavieja, Sodium pumps adapt spike bursting to stimulus statistic, Nature Neuroscience 10, 1467-1473 (2007). 2006 V. K. Vanag, D.G. Míguez, I. R. Epstein, Designing an Enzymatic Oscillator: Bistability and Feedback Control led Oscillations with Glucose Oxidase in a CSTR, J. Phys. Chem. 125, 194515 (2006). D.G. Míguez, S. Alonso, A.P. Muñuzuri, F. Sagués, Experimental evidence of localized oscillations in the photosensitive chlorine dioxide-iodine-malonic acid reaction, Phys. Rev. Lett, 97, 178301 (2006). D. G. Míguez, A. P. Muñuzuri, On the orientation of stripes in fish skin patterning, Biophys. Chem. 124, 161 (2006). D. G. Míguez, R. A. Satnoianu, A. P. Muñuzuri, Experimental steady pattern formation in reaction-diffusion-advection systems, Phys. Rev. E 73, 025201 (R) (2006). D. G. Míguez, M. Dolnik, A. P. Muñuzuri, L. Kramer, Effect of Axial Growth on Turing Pattern Formation. Phys. Rev. Lett 96, 048304 (2006). D. G. Míguez, G. Izús, A. P. Muñuzuri, Robustness and Stability of Flow-and-Diffusion Structures, Phys. Rev. E 73, 016207 (2006). R. Guantes and J. F. Poyatos, Dynamical principles of two-component genetic oscillators, PLoS Computational Biology 2, e30 (2006). 2005 D. G. Miguez, V. Perez-Villar, and A. P. Munuzuri, Turing instability controlled by spatiotemporal imposed dynamics, Phys. Rev. E 71, 066217 (2005). R. Guantes and G. G. de Polavieja, "Variability in noise-driven integrator neurons", Physical Review E 71, 011911 (2005). S. C. Farantos, S. Stamatiadis, L. Lathouwers and R. Guantes, "Grid enabled molecular dynamics: classical and quantum algorithms", Lecture Series on Computer and Computational Sciences 1, 1-16 (2005). 2004 F. Sagués, D. G. Míguez, E. M. Nicola, A. P. Muñuzuri, J. Casademunt, L. Kramer, Travelling-stripe forcing of Turing patterns, Physica D 199, 235 (2004). D. G. Míguez, E. M. Nicola, A. P. Muñuzuri, J. Casademunt, F. Sagués, L. Kramer, Traveling-Stripe Forcing Generates Hexagonal Patterns, Phys. Rev. Lett. 93, 048303 (2004). M. Kærn‡, D. G. Míguez‡, A. P. Muñuzuri, M. Menzinger, Control of chemical pattern formation by a clock-and-wavefront type mechanism, Biophys. Chem. 110, 231 (2004). Shared 1st authorship. S. Sengupta, R. Guantes, S. Miret-Artés and P. Hänggi, "Controlling directed transport in two-dimensional periodic structures under crossed electric fields", Physica A 338, 406 (2004). R. Guantes, A. S. Sanz, J. Margalef-Roig and S. Miret-Artés, "Atom-surface diffraction: a trajectory description", Surface Science Reports 53, 199-330 (2004). R. Guantes, J. L. Vega, S. Miret-Artés and Eli Pollak, "Hamiltonian theory for vibrational lineshapes of atoms adsorbed on surfaces", Journal of Chemical Physics 120, 10768 (2004). J. L. Vega, R. Guantes and S. Miret-Artés, "Quasielastic and low vibrational lineshapes in atom-surface diffusion", Journal of Physics: Condensed Matter 16, S2879 (2004). J. L. Vega, R. Guantes, S. Miret-Artés and D. A. Micha, "Collisional lineshapes for low frequency vibrations of an atom adsorbed on a metal surface", Journal of Chemical Physics 121, 8580 (2004) 2003 B. Peña, C. Pérez-García, A. Sanz-Anchelergues, D. G. Míguez, A. P. Muñuzuri, Transverse instabilities in chemical Turing patterns of stripes, Phys. Rev. E 68, 056206 (2003). S. Rüdiger, D. G. Míguez, A. P. Muñuzuri, F. Sagués, J. Casademunt, Dynamics of Turing Patterns under Spatiotemporal Forcing, Phys. Rev. Lett 90, 128301 (2003). R. Guantes and S. Miret-Artés, "Chaotic transport of particles in two-dimensional periodic potentials driven by ac forces", Physical Review E 67, 046212 (2003). R. Guantes, J. L. Vega, S. Miret-Artés and Eli Pollak, "Kramers' turnover theory for diffusion of Na atoms on a Cu(001) surface measured by He scattering", Journal of Chemical Physics 119, 2780 (2003).     Labs & Groups From around the world     Courses Host & view classes     Protocols Share techniques & more     Blogs Read OWW blogs