Difference between revisions of "SynBERC:Seminar series/Remy Chait"

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==Remote participation==
 
==Remote participation==
This talk will be webcast and video archived online (barring technical difficulties)Details coming soon.
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To submit questions during the talk, you must have an [[Join|OpenWetWare account]]Type questions into the [[Special:Chat |chat room]].
  
To submit questions during the talk, you must have an [[Join|OpenWetWare account]]Type questions into the [[Special:Chat |chat room]].
+
A video stream of the talk will be available for real-time viewingJust point Quicktime or [http://www.videolan.org/vlc/ VLC] to the following stream:
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'''rtsp://caprica.csail.mit.edu/SynBERC.sdp'''

Revision as of 07:49, 24 April 2007

Antibacterial drug combinations and evolution of drug resistance
Remy Chait, Harvard Systems Biology
April 24, 2007
12-1pm
68-181, MIT

The rapid evolution of bacterial drug resistance and the alarming slowdown in development of new antibiotics is spurring attention towards multi-drug treatments. But how do such treatments affect the rate of evolution of drug resistance? I will present a simple model and direct experimental measurements showing that non-additive interactions between the drugs can profoundly alter the fitness landscape, leading to surprising and counterintuitive outcomes.

Reference

  1. Chait R, Craney A, and Kishony R. Antibiotic interactions that select against resistance. Nature. 2007 Apr 5;446(7136):668-71. DOI:10.1038/nature05685 | PubMed ID:17410176 | HubMed [Chait-Nature-2007]

Remote participation

To submit questions during the talk, you must have an OpenWetWare account. Type questions into the chat room.

A video stream of the talk will be available for real-time viewing. Just point Quicktime or VLC to the following stream:

rtsp://caprica.csail.mit.edu/SynBERC.sdp