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Our research is focused on Metabolic Engineering - the improvement of cellular properties, using modern genetic tools. This field encompasses two important components:

  • The modification of biochemical pathways inside cells and
  • The rigorous evaluation of the resulting cellular phenotypes.

Our most recent research has been focused on the following topics:

To accomplish the above goals we make use of a diverse array of scientific tools and methods, many of which have also become areas of research for our group:

  • Bioinformatics and Systems Biology - Our group was one of the first to realize the importance of computational tools for handling the large volume of data generated by microarrays and other technologies.
  • DNA microarrays - We have developed full genome microarrays for Synechocystis Sp., and partial microarrays for C. glutamicum, E. coli, and the mouse genomes.

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Department of Chemical Engineering

Massachusetts Institute of Technology

77 Massachusetts Ave,

Room 56-469

Cambridge, MA 02139


Last Modified:
Monday, March 3, 2008 - by afi.


office | 617.258.0398

lab | 617.253.6591

lab | 617.258.0349

lab | 617.253.6521

fax | 617.253.3122