Difference between revisions of "Stephanopoulos:Projects"

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* the modification of biochemical pathways inside cells and
 
* the modification of biochemical pathways inside cells and
 
* the rigorous evaluation of the resulting cellular phenotypes.
 
* the rigorous evaluation of the resulting cellular phenotypes.
 
+
<p><p>
 
   
 
   
 
Our most recent research has been focused on the following topics:
 
Our most recent research has been focused on the following topics:
  
* Metabolic Engineering of <i>E.Coli</i> for the production of biochemicals
+
* [[Stephanopoulos Lab:Production of biochemicals in E. coli | '''Metabolic Engineering of <i>E.Coli</i> for the production of biochemicals''']]
  
* Inverse Metabolic Engineering
+
* [[Stephanopoulos Lab:Inverse Metabolic Engineering | '''Inverse Metabolic Engineering''']]
  
* gTME
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* [[Stephanopoulos Lab:gTME | '''gTME''']]
  
* Flux Determination
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* [[Stephanopoulos Lab:Flux Determination | '''Flux Determination''']]
  
* Hepatocyte Physiology
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* [[Stephanopoulos Lab:Hepatocyte Physiology | '''Hepatocyte Physiology''']]
  
* Metabolomics
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* [[Stephanopoulos Lab:Metabolomics | '''Metabolomics''']]
  
* Systems Biology
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* [[Stephanopoulos Lab:Systems Biology | '''Systems Biology''']]
  
 
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Revision as of 16:04, 12 July 2006

<html> <align=left><h1 style="color:maroon">Research</h1></align> </html> Our research is focused on Metabolic Engineering - the improvement of cellular properties, using modern genetic tools. This field encompasses two important components:
  • the modification of biochemical pathways inside cells and
  • the rigorous evaluation of the resulting cellular phenotypes.

<p> Our most recent research has been focused on the following topics:

<html> <br> To accomplish the above goals we make use of a diverse array of scientific tools and methods, many of which have also become areas of research for our group: <ul> <p> <li> <b><a href="Bioinfo.shtml">Bioinformatics and Systems Biology</a></b> - Our group was one of the first to realize the importance of computational tools for handling the large volume of data generated by microarrays and other technologies. <li> <b><a href="Fluxes.shtml">Methods for intracellular flux determination</a></b> - Fluxes are determined by material balancing, NMR fine spectra analysis and GC-MS measurements. <li> <b><a href="Microarray.shtml">DNA microarrays</a></b> - We have developed full genome microarrays for <i>Synechocystis</i> Sp., and partial microarrays for <i>C. glutamicum</i>, <i>E. coli</i>, and the mouse genomes. <li> <b><a href="BioReactor.shtml">Bioreaction network analysis.</a></b> <br> </html> <html> <tr><td><br></td></tr> <!---Blank Line----> <div style="position: relative; width: 750px; height: 20px; overflow: hidden"> <div style="position: absolute; top: 0px; left: 0px; z-index: 2"> <img src="/images/6/69/Ban_2_dsm.gif" alt="" width="750" height="20" longdesc="/wiki/Image:Ban_2_dsm.gif"/> </a></div> </div> <!---Maroon bar---> </html>

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<tr><td width=750 valign="top"> <!---Footer Info Table----> <table width=750 border=0 cellpadding=0 cellspacing=0> <tr><td align="left" width="250" valign="top"> <font color="maroon"><tt>Address</tt></font><br> <small> Massachusetts Institute of Technology<br> Department of Chemical Engineering<br> Cambridge, MA 02139<br> Room 56-469 </small> </td> <td align="center" width="250" valign="top"> <small> <a href="http://www.mit.edu">MIT</a> | <a href="/wiki/Stephanopoulos_Lab">HOME</a><br> Last Modified:<br>Monday, July 10th, 2006 - by <a href="Adrian.shtml">afi</a>. </small> <br> <font color="#990000"><tt>gnswebpage-www@mit.edu</tt></font> </td> <td align="right" width="250" valign="top"> <font color="#990000"><tt>Telephones</tt><br></font> <small> office | 617.258.0398<br> lab | 617.253.6591<br> lab | 617.258.0349<br> lab | 617.253.6521<br> fax | 617.253.3122<br> </small> </td></tr> </table></td></tr>

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