Sobeck Lab:Publications

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- Sareen A, Chaudhury I, Adams N, Sobeck A: Fanconi Anemia Proteins FANCD2 and FANCI exhibit different DNA damage responses during S-phase. Nucleic Acids Res, in press.

- Sobeck A, Stone S, Landais I, de Graaf B, Hoatlin ME (2009): The fanconi anemia protein FANCM is controlled by FANCD2 and the ATR/ATM pathways. J Biol Chem 284: 25560-8. [1]

- Landais I*, Sobeck A*, Stone S*, LaChapelle A, Hoatlin ME (2009): A novel cell-free screen identifies a potent inhibitor of the Fanconi anemia pathway. Int. J. Cancer, 124:783-92. (Cover) [2]

- Waltes R, Kalb R, Gatei M, Kijas AW, Stumm M, Sobeck A, Wieland B, Varon R, Lerenthal Y, Lavin MF, Schindler D, Dörk T (2009): Human RAD50 deficiency in a Nijmegen breakage syndrome-like disorder. Am J Hum Genet. 84: 605-16. [3]

- Xu D*, Guo R*, Sobeck A, Bachrati CZ, Yang J, Enomoto T, Brown GW, Hoatlin ME, Hickson ID, Wang W (2008): RMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stability. Genes Dev 22: 2843-55. [4]

- Sobeck A, Stone S, Hoatlin ME (2007): DNA Structure-Induced Recruitment and Activation of the Fanconi Anemia Pathway Protein, FANCD2. Mol Cell Biol 27: 4283-92. [5]

- Stone S, Sobeck A, Margriet van Kogelenberg, Bendert de Graaf, Hans Joenje, Jan Christian, Hoatlin ME (2007):Identification, Developmental Expression, and Regulation of the Xenopus Ortholog of Human FANCG/XRCC9. Genes Cells, 12: 841-51. [6]

- Sobeck A*, Stone S*, Costanzo V, de Graaf B, Reuter T, de Winter J, Wallisch M, Akkari Y, Olson S, Wang W, Joenje H, Christian JL, Lupardus PJ, Cimprich KA, Gautier J, Hoatlin ME (2006): Fanconi anemia proteins are required to prevent accumulation of replication-associated DNA double-strand breaks. Mol Cell Biol 26: 425-37. (Cover]) [7]

- Yin J*, Sobeck A*, Xu C*, Meetei AR, Hoatlin M, Li L, Wang W (2005): BLAP75, an essential component of Bloom's syndrome protein complexes that maintain genome integrity. EMBO J. 24: 1465-76. [8]

- Leveille F, Blom E, Medhurst AL, Bier P, Laghmani el H, Johnson M, Rooimans MA, Sobeck A, Waisfisz Q, Arwert F, Patel KJ, Hoatlin ME, Joenje H, de Winter JP (2004): The Fanconi anemia gene product FANCF is a flexible adaptor protein. J Biol Chem. 279: 39421-30. [9]

- U. Oppitz, U. Bernthaler, D. Schindler, A. Sobeck, H. Hoehn, M. Platzer, A. Rosenthal, and M Flentje (1999): Sequence Analysis of the ATM Gene in 20 Patients with RTOG grade 3 or 4 Acute and/or Late Tissue Radiation Side Effects. Int. J. Radiation Oncology Biol. Phys. 44, 981-988. [10]

- K.J. Erb, J.W. Holloway, A. Sobeck, H. Moll, G. Le Gros (1998): Infection of mice with Mycobacterium bovis-Bacillus Calmette-Guerin (BCG) suppresses allergen-induced airway eosinophilia. J Exp Med 187:561-9. [11]


1. H. Hoehn, M. Gross, D. Schindler, A. Sobeck and M. Wagner, Genetic Instability and Fanconi Syndrome. In: F.M. Hisami, S.M. Weissman and G.M. Martin, Editors, Chromosomal Instability and Aging. Marcel Dekker, New York (2003), pp. 375–408.

2. Sobeck and M. Wagner (2002): Interactions between Fanconi and RAD51 Proteins in the Yeast 2-Hybrid System (german). Medizinische Genetik Edition 2: Fanconi Anaemie.

3. D. Schindler, A. Sobeck (1999): Diagnostics of Ataxia telangiectasia by flow cytometry and cell cycle analysis (german). Medizinische Genetik Edition Band 1: Ataxia teleangiectatica.