Silver: RNA Dynamics

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Dynamics of RNAs

The importance of RNAs in regulation of cell determination and disease continues to grow. We study the dynamics of RNAs including co-transcriptional alternative splicing and transport. We use a combination of genetic, biochemical and novel genomic and imaging approaches to study RNA dynamics on a systems-wide level. We have generated a spatial and temporal map of the expression of all RNA-binding proteins in mammalian neural development.