Silver: RNA Dynamics: Difference between revisions

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===Dynamics of RNAs===
===Dynamics of RNAs===


The importance of RNAs in regulation of cell determination and disease continues to grow. We study the dynamics of RNAs including co-transcriptional alternative splicing and transport ([[User: IanSwinburne |IanSwinburne]]). We use a combination of genetic, biochemical and novel genomic and imaging approaches to study RNA dynamics on a systems-wide level in both model organisms (yeast and fly) and human cells, eg ([[User: NatalieGilks |NatalieGilks]], [[User: OonaJohnstone |OoonaJohnstone]]  and [[User: MichaelMoore |MichaelMoore]]). We have generated a spatial and temporal map of the expression of all RNA-binding proteins in mammalian neural development ([[User: AdrienneMckee |AdrienneMckee]]).  One goal is to decode the way that proteins recognize RNA throughout the genome.
The importance of RNAs in regulation of cell determination and disease continues to grow. We study the dynamics of RNAs including co-transcriptional alternative splicing and transport ([[User: IanSwinburne |IanSwinburne]]). We use a combination of genetic, biochemical and novel genomic and imaging approaches to study RNA dynamics on a systems-wide level in both model organisms (yeast and fly) and human cells, eg ([[User: NatalieGilks |Natalie Gilks]], [[User: OonaJohnstone |Oona Johnstone]]  and [[User: MichaelMoore |Michael Moore]]). We have generated a spatial and temporal map of the expression of all RNA-binding proteins in mammalian neural development ([[User: AdrienneMckee |Adrienne Mckee]]).  One goal is to decode the way that proteins recognize RNA throughout the genome.

Revision as of 10:20, 9 December 2005

Dynamics of RNAs

The importance of RNAs in regulation of cell determination and disease continues to grow. We study the dynamics of RNAs including co-transcriptional alternative splicing and transport (IanSwinburne). We use a combination of genetic, biochemical and novel genomic and imaging approaches to study RNA dynamics on a systems-wide level in both model organisms (yeast and fly) and human cells, eg (Natalie Gilks, Oona Johnstone and Michael Moore). We have generated a spatial and temporal map of the expression of all RNA-binding proteins in mammalian neural development (Adrienne Mckee). One goal is to decode the way that proteins recognize RNA throughout the genome.