Difference between revisions of "Silver: Publications"

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[[Silver: Publications (1990-1999) | 1990-1999]]
[[Silver: Publications (1990-1999) | 1990-1999]]
*Phillips I, Silver P, A New Biobrick Assembly Strategy Designed for  Facile Protein Engineering, MIT Synthetic Biology Working Group Reports, published online 20 April 2006 at [https://dspace.mit.edu/handle/1721.1/32535 MIT dspace] (doi: 1721.1/32535)
*Swinburne, IA., Meyer, CA., Liu, S., Silver, PA, and Brodsky, AS.  Genomic localization of RNA binding proteins reveals links between pre-mRNA processing and transcription,  2006.  Genome Research, accepted.
*Drubin, DA., Garakani, AM., and Silver, PA.  Motion as phenotype.  The use of live-cell imaging and machine visual screening to characterize transcription-dependent chromosome dynamics.  2006.  BMC Cell Biology, 7:19. [http://www.biomedcentral.com/1471-2121/7/19/abstract Abstract].
*Brown, CR and Silver, PA.  Poreing the right dose. 2006.  Nature Cell Biology.
*Auld, KL., Brown, CR., Casolari, JM., Komili, S. and Silver, PA.  Genomic Association of the Proteasome Demonstrates Overlapping Gene Regulatory Activity with Transcription Factor Substrates.  2006. Molecular Cell, 21:861-871. [http://www.molecule.org/content/article/abstract?uid=PIIS1097276506001420 Absract].
*Bachand, F., Lackner, D., Bahler, J., and Silver, PA.  Autoregulation of ribosome bio-synthesis by a translational response in fission yeast.  2006.  Mol Cell Biol., 26:1731-42. [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16478994&query_hl=10&itool=pubmed_docsum Absract]
*Vandegraaff, N., Devroe, E., Turlure, F., Silver, P.A., and Engelman, A.  Genetic and biochemical analyses of integrase-interaction proteins lens epithelium-derived growth factor (LEDGF/p75) and hepatoma-derived growth factor 2 (HRP2) in preintegration complex formation and HIV replication.  2006, Virology, in press. [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16337983&query_hl=10&itool=pubmed_docsum Abstract]
*Hitchcock, A.L., Kahana, J.A., and Silver, P.A.  The uses of green fluorescent protein in yeasts.  2006.  Methods Biochem Anal. 47:179-201
*Robinson, M.A., Park, S., Sun, Z.Y., Silver, P.A., Wagner,  G., and Hogle, J.M. Multiple conformations in the ligand-binding  site of the yeast nuclear pore targeting domain of Nup116p <B>J.  Biol. Chem.</B> 2005. Aug 16. [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16105837&query_hl=1 Abstract]
*Brodsky, A.S., Meyer, C.A., Hall, G., Swinburne, I.A., Keenan,  B.J., Liu, X.S., Fox, E.A., and., Silver, P.A. Genomic mapping  of RNA Polymerase II reveals sites of co-transcriptional regulation  in human cells. <B>Genome Biology.</B> 2005. Jul 15:6(8): R64  [http://genomebiology.com/2005/6/8/R64/abstract Abstract]
*McKee, A.E., Minet, E., Stern, C., Riahi, S., Stiles, C.D.,  and., Silver, P.A. A genome-wide in situ hybridization map of  RNA-binding proteins reveals anatomically restricted expression  in the developing mouse brain. <B>BMC Dev Biol.</B> 2005. July  20;5(1):14 [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16033648&query_hl=1 Abstract]
*Carrol, J.S., Liu, X.S., C.R., Brodsky, A.S., Meyer, C.A.,  Li, W., Szary, A., Shao, W., Hesterman, E., Geistlinger, T.R.,  Fox, E.A., Silver, P.A., and Brown, M. Chromosome-wide mapping  of estrogen receptor binding reveals long-range combinatorial  regulation requiring forkhead proteins. <B>Cell.</B> 2005. July  15;122(1):33-43 [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16009131&query_hl=1 Abstract]
*Park, S., Isaacson, R., Kim, H.T., Silver, P.A., and Wagner,  G. Ufd1 exhibits the AAA-ATPase fold with two distinct ubiquitin  interaction sites. <B>Structure (Camb)</B> 2005. Jul; 13(7):995-1005.  [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15844952&query_hl=1 Abstract]
*Casolari, J.M., Brown, C.R., Drubin, D.A., Rando, O.J., and  Silver, P.A. Developmentally induced changes in transcriptional  program alter spatial organization across chromosomes. <B>Genes  Dev.</B> 2005. May 15;19(10):1188-98. [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15905407&query_hl=1 Abstract]
*Schroeder, F.C., Kau, T.R., Silver, P.A., and Clardy, J. The  psammaplysenes, specific inhibitors of FOXO1a nuclear export.  <B>J Nat Prod</B> 2005. Apr; 68(4):574-6. [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15844952&query_hl=1 Abstract]
*Devroe, E., Silver, P.A., and Engelman, A. HIV-1 incorporates  and proteolytically processes human NDR1 and NDR2 serine-threonine  kinases. <B>Virology</B> 2005. Jan 5; 331(1):181-9. [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15582665 Abstract]
*Hieronymus, H., and Silver, P.A. A systems view of mRNP biology.  <B>Genes Dev.</B> 2004. Dec 1,18(23):2845-60.[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15574591 Abstract]
*Lu, R., Limon, A., Devroe, E., Cherepanov, P., Silver, P.A.,  and Engelman, Class II integrase mutants with changes in putative  nuclear localization signals are primarily blocked at a post-nuclear  entry step of human immunodeficiency virus type 1 replication.  <B>J. Virol.</B> 2004. Dec; 78(23):12735-46.[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15542626 Abstract]
*Hieronymus, H., Yu, M.C., and Silver, P.A. Genome-wide mRNA  surveillance is coupled to the mRNA export. <B>Genes Dev.</B> 2004.  Nov 1; 18(21):2652-62.[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15489286 Abstract]
*Silver, P.A. and Way, Jeffrey. The potential for synthetic  biology. <B>The Scientist.</B> 2004. Sept. 27; 18(18);30-1. [http://www.the-scientist.com/yr2004/sep/research2_040927.html Epub]
*Cherepanov, P., Devroe, E., Silver, P.A., and Engelman, A.  Identification of an evolutionarily-conserved domain in LEDGF/p75  that binds HIV-1 integrase. <B>J. Biol. Chem.</B> 2004; Sept. 14. [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15371438 Epub]
*Turlure, F., Devroe, E., Silver, P.A., and Engelman, A. Human  cell proteins and human immunodeficiency virus DNA integration.  <B>Front Biosci.</B> 2004; Sept. 1; 9:3187-208. [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15353349 Abstract]
*Yu, M.C., Bachand F., McBride, A.E., Komili, S., Casolari,  J.M., and Silver, P.A. Arginine methyltransferase affects interactions  and recruitment of mRNA processing and export factors. <B>Genes  Dev</B> 2004, Aug. 15. 18(16):2024-35. [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15314027 Abstract]
*McKee A.E.. and Silver, P.A. REF-ereeing the cytoplasmic fate  of mRNA via nuclear export. <B>Dev Cell</B> 2004. July  7; 23(13):2641-50.[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15177019 Abstract]
*Bachand, F. and Silver, P.A. PRMT3 is a ribosomal protein  methyltransferase that affects the cellular levels of ribosomal  subunits. <B>EMBO J</B> 2004. July 7; 23(13):2641-50.[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15175657 Abstract]
*Casolari, J.M., Brown, C.R., Komili, S., West, J., Hieronymus,  H., and Silver, P.A. Genome-wide localization of the nuclear  transport machinery reveals coupling of transcriptional status  and nuclear organization. <B>Cell.</B> 2004. May 14; 117(4):427-39.[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15137937 Abstract]
*Casolari, J.M. and Silver, P.A. Guardian at the gate: preventing  unspliced pre-mRNA export. <B>Trends Cell B iol.</B> 2004.  May, 14(5):222-5 [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15130577 Abstract]
*Devroe, E., Erdjument-Bromage, H., Tempst, P., and Silver,  P.A. Human Mob proteins regulate the NDR1 and NDR2 serine-threonine  kinases. <B>JBC.</B> April 2, 2004. [http://www.jbc.org/cgi/content/abstract/M401999200v1 Abstract]
*Devroe, E., and Silver, P.A. Therapeutic potential of retroviral  RNAi vectors <B>Expert Opin. Biol. Ther.</B> 2004; 4(3):319-27.
*Kau, T.R., Way, J.C., and Silver, P.A. Nuclear transport and  cancer: from mechanism to intervention. <B>Nat. Rev. Cancer. </B> 2004; Feb; 4(2):106-17. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14732865 Abstract]
*Jiang, Y., Minet, E., Zhang, Z., Silver, P.A., and Bai, M.  Modulation of interprotomer relationship is important for activation  of dimeric calcium-sensing receptor. <B>J. Biol. Chem.</B> 2004. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14729680 Abstract]
*Kau, T.R., Schroeder, F., Ramazwamy, S., Wojciechowski, C.L.,  Zhao, J.J., Roberts, T.M., Clardy, J., Sellers, W.R., and Silver,  P.A. A Chemical genetic screen identifies inhibitors of regulated  nuclear export of a Forkhead transcription factor in PTEN deficient  tumor cells. <B>Cancer Cell.</B> 2003; 4(6):463-76. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14706338 Abstract]
*Haggarty, S.J., Koeller, K.M., Kau, T.R., Silver, P.A., Roberge,  M., and Schreiber, S.L. Small molecule modulation of the human  chromatid decatenation checkpoint. <B>Chem. Biol.</B> 2003; 10(12):1267-79.  [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14700634 Abstract]
*Hitchcock, A.L., Auld, K., Gygi, S.P., and Silver, P.A. A  subset of membrane-associated proteins is ubiquitinated in response  to mutations in the endoplasmic reticulum degradation machinery.  <B>Proc. Nat. Acad. Sci</B>.<B></B> 2003, 100(22):12735-40.[http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14557538&dopt=Abstract Abstract]
*Devroe, E., Engelman, A., and Silver, P.A. Intracellular transport  of human immunodeficiency virus type 1 integrase <B>J. Cell.  Sci.</B> 2003; 116(Pt21):4401-8. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=13130095&dopt=Abstract Abstract]
*Brodsky, A.S,, Johnston, A.P,, Trau, M., and Silver, P.A.  Analysis of RNA-protein interactions by flow cytometry. <B>Curr.  Opin. Mol. Ther</B> 2003; 5(3):235-40. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12870432&dopt=Abstract Abstract]
*Kau, T.R. and Silver, P.A. Nuclear transport as a target for  cell growth. <B>Drug Discov. Today.</B> 2003; 8(2):78-85. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12565010&dopt=Abstract Abstract]
*Hieronymus, H. and Silver, P.A. Genome-wide analysis of RNA-protein  interactions illustrates specificity of the mRNA export machinery.  <B>Nat. Genet.</B> 2003; 33(2):155-61. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12524544&dopt=Abstract Abstract]
*Beilharz T., Egan, B., Silver, P.A. Hofmann, K., and Lithgow,  T. Bipartite signals mediate subcellular targeting of tail-anchored  membrane protein in saccharomyces cerevisiae. <B>J. Biol. Chem. </B> 2003; [epub ahead of print].[http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12514182&dopt=Abstract Abstract]
*Damelin, M. and Silver, P.A. In situ analysis of spatial relationships  between proteins of the nuclear pore complex. <B>Biophys J.</B> 2002;  83(6): 3626-36.[http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12496130&dopt=Abstract Abstract]
*Brodsky, A.S. and Silver, P.A. A microbead-based system for  identifying and characterizing RNA-protein interactions by flow  cytometry. <B>Mol Cell Proteomics</B> 2002; 1(12): 922-9. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12543929&dopt=Abstract Abstract]
*Lei, E.P., Stern, C.A., Fahrenkrog, B., Krebber, H., Moy,  T.I., Aebi, U. and Silver, P.A., Sac3 is an mRNA export factor  that localizes to the cytoplasmic fibrils of the nuclear pore  complex. <B>Mol Biol Cell</B> 2002; <I>In Press.</I>
*Lei, E. P. and Silver, P.A. Intron status and 3'-end formation  control cotranscriptional export of mRNA. <B>Genes Dev</B> 2002;  16: 2761-2766. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12414728&dopt=Abstract Abstract]
*Limon A., Devroe, E., Lu, R., Ghory, H.Z., Silver, P.A., and  Engelman, A. Nuclear localization of human immunodeficiency virus  type 1 preintegration complexes (PICs): V165A and R166A are pleiotropic  integrase mutants primarily defective for integration, not PIC  nuclear import. <B>J Virol.</B> 2002; 76(21): 10598-607.[http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12368302&dopt=Abstract Abstract]
*Devroe, E. and Silver, P.A. Retrovirus-delivered siRNA. <B>BMC  Biotechnol.</B> 2002; 2(1): 15. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12199908&dopt=Abstract Abstract]
*Moy, T.I., and Silver, P.A. Requirements for the nuclear export  of the small ribosomal subunit. <B>J Cell Sci</B> 2002; 115 (Pt  14): 2985-95.[http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12082158&dopt=Abstract Abstract]
*Damelin, M., Silver, P.A., and Corbett, A.H. Nuclear protein  transport. <B>Methods Enzymol.</B> 2002; 351:587-607.
*Brodsky, A..S. and Silver, P.A. Identifying proteins that  affect mRNA localization in living cells. <B>Methods</B> 2002;  26(2):151-5.
*Moy, T.I., Boettner, D., Rhodes, J.C., Silver, P.A., and Askew,  D.S. Identification of a role for Saccharomyces cerevisiae Cgr1p  in pre-rRNA processing and 60S ribosome subunit synthesis. <B>Microbiology </B> 2002; 148 (Pt 4): 1081-1090. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11932453&dopt=Abstract Abstract]
*Damelin, M., Simon, I., Moy, T.I., Wilson, B., Komili, S.,  Tempst, P., Roth, F.P., Young, R.A., Carins, B.R., and Silver,  P.A. The genome-wide localization of Rsc9, a component of the  RSC chromatin-remodeling complex, changes in response to stress.  <B>Mol Cell</B> 2002; 9 (3): 563-73. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11931764&dopt=Abstract Abstract]
*Lei, E.P. and Silver, P.A. Protein and RNA export from the  nucleus. <B>Dev Cell.</B> 2002; 2 (3): 261-72. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11879632&dopt=Abstract Abstract]
*Valentini, S.R., Casolari, J.M., Oliveira, C.C., Silver, P.A.  and McBride, A.E. Genetic interactions of yeast eukaryotic translation  initiation factor 5A (eIF5A) reveal connections to poly(A)-binding  protein and protein kinase C signaling. <B>Genetics</B> 2002;  160 (2): 393-405. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11861547&dopt=Abstract Abstract]
*Hitchcock, A.L., Krebber, H., Frietze, S., Lin, A., Latterich,  M., and Silver, P.A. The conserved Npl4 protein complex mediates  proteasome-dependent membrane-bound transcription factor activation.  <B>Mol Biol Cell</B> 2001; 12 (10): 3226-3241. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11598205&dopt=Abstract Abstract]
*Lei, E.P., Krebber, H., and Silver, P.A. Messenger RNAs are  recruited for nuclear export during transcription. <B>Genes Dev. </B> 2001; 15(14): 1771-1782. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11459827&dopt=Abstract Abstract]
*McBride, A.E. and Silver, P.A. State of the Arg: Protein methylation  at arginine comes of age. <B>Cell</B> 2001; 106(1): 5-8.
*Tham, W., Wyithe, J.S., Ferrigno, P.K., Silver, P.A., and  Zakian, V.A. Localization of yeast telomeres to the nuclear periphery  is separable from transcriptional repression and telomere stability  functions. <B>Mol Cell</B> 2001; 8(1): 189-199. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11511372&dopt=Abstract Abstract]
*Hood, J.K., Hwang, W.W., and Silver, P.A. The Saccharomyces  cerevisiae cyclin Clb2p is targeted to multiple subcellular locations  by cis- and trans-acting determinants. <B>J. Cell Sci.</B> 2001;  114 (3): 589-597. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11171327&dopt=Abstract Abstract]
*Brodsky, A.S. and Silver, P.A. Pre-mRNA processing factors  are required for nuclear export. <B>RNA</B> 2000; 6(12): 1737-1749.[http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11142374&dopt=Abstract Abstract]
*Colas, P., Cohen, B., Ferrigno, P.K., Silver, P.A., and Brent,  R. Targeted modification and transportation of cellular proteins.  <B>Proc.Natl.Acad.Sci. USA</B> 2000 Dec 5; 97(25): 13720-13725.  [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11106396&dopt=Abstract Abstract]
*Weiss, V. H., McBride, A. E., Kim, H. K., Hogle, J. M., and  Silver, P. A. The structure and oligomerization of the yeast  arginine methyltransferase, Hmt1. <B>Nat. Struct. Biol.</B> 2000;  7: 1165-1171. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11101900&dopt=Abstract Abstract]
*Stage-Zimmermann, T., Schmidt, U. and Silver, P.A. Factors  Affecting Nuclear Export of the 60S Ribosomal Subunit In Vivo.  <B>Mol Biol Cell</B> 2000 Nov;11(11):3777-3789. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11071906&dopt=Abstract Abstract]
*Krebber, H. and Silver, P.A. Directing proteins to nucleus  by fusion to nuclear localization signal tags. <B>Methods Enzymol</B>  2000;327:283-96. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11044991&dopt=Abstract Abstract]
*Prinz, W.A., Grzyb, L., Veenhuis, M., Kahana, J.A., Silver,  P.A. and Rapoport, T.A. Mutants affecting the structure of the  cortical endoplasmic reticulum in Saccharomyces cerevisiae. <B>J  Cell Biol</B> 2000 Aug 7;150(3):461-74. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10931860&dopt=Abstract Abstract]
*Hood, J.K. and Silver, P.A. Diverse nuclear transport pathways  regulate cell proliferation and oncogenesis.<B> Biochim Biophys  Acta</B> 2000 Jul 31;1471(1):M31-41. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10967423&dopt=Abstract Abstract]
*Shen, E.C., Stage-Zimmermann, T., Chui, P., and Silver, P.A.  The yeast mRNA binding protein Npl3p interacts with the Cap Binding  Complex. <B>J. Biol. Chem.</B> 2000 May 22. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10823828&dopt=Abstract Abstract]
*Ferrigno, P. and Silver, P.A. Polyglutamine expansions: proteolysis,  chaperones, and the dangers of promiscuity. <B>Neuron</B> 2000  Apr;26(1):9-12. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10798387&dopt=Abstract Abstract]
*Hood, J.K., Casolari, J.M., and Silver, P.A. Nup2p is located  on the nuclear side of the nuclear pore complex and coordinates  Srp1p/importin-alpha export. <B>J. Cell Sci.</B> 2000 Apr;113  (Pt 8):1471-80. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10725229&dopt=Abstract Abstract]
*Jones, A.L., Quimby, B.B., Hood, J.K., Ferrigno, P., Keshava,  P.H., Silver, P.A., and Corbett, A.H. SAC3 may link nuclear protein  export to cell cycle progression. <B>Proc. Natl. Acad. Sci. USA</B>  2000 Mar 28;97(7):3224-9. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10716708&dopt=Abstract Abstract]
*McBride, A.E., Weiss, V.H., Kim, H.K., Hogle, J.M., and Silver,  P.A. Analysis of the yeast arginine methyltransferase Hmt1p/Rmt1p  and its in vivo function. Cofactor binding and substrate interactions.  <B>J. Biol. Chem.</B> 2000 Feb 4;275(5):3128-36. [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10652296&dopt=Abstract Abstract]
*Damelin, M. and Silver, P.A. Mapping interactions between  nuclear transport factors in living cells reveals pathways through  the nuclear pore complex. <B>Mol. Cell</B> 2000; 5: 133-140.  [http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10678175&dopt=Abstract Abstract]

Revision as of 13:21, 30 April 2006

2000 to present



  • Morehouse, H., Buratowski, R.M., Silver, P.A., and Buratowski, S. The importin/karyopherin kap114 mediates the nuclear import of TATA-binding protein. Proc. Natl. Acad. Sci. U.S.A. 1999; 96(22):12542-7.
  • Ferrigno, P. and Silver, P.A. Regulated nuclear localization of stress-responsive factors: how the nuclear trafficking of protein kinases and transcription factors contributes to cell survival. Oncogene 1999; 18(45):6129-34.
  • Moy, T.I. and Silver, P.A. Nuclear export of the small ribosomal subunit requires the ran-GTPase cycle and certain nucleoporins. Genes & Dev. 1999; 13(16):2118-33.
  • Krebber, H., Taura, T., Lee, M.S., and Silver, P.A. Uncoupling of the hnRNP Npl3p from mRNAs during the stress-induced block in mRNA export. Genes & Dev. 1999;13(15):1994-2004.
  • Brodsky, A.S. and Silver, P.A. Nuclear transport HEATs up. Nat. Cell. Biol. 1999;1(3):E66-E67.
  • Zeng, X., Kahana, J.A., Silver, P.A., Morphew, M.K. McIntosh,J.R.,Fitch, I.T., Carbon, J., and Saunders, W.S. Slk19p is a centromere protein that functions to stabilize mitotic spindles. J. Cell. Biol. 1999;146(2):415-25.
  • Defossez, P.A., Prusty, R., Kaeberlein, M., Lin, S.J., Ferrigno, P., Silver, P.A., Keil, R.L., and Guarente, L. Elimination of replication block protein Fob1 extends the life span of yeast mother cells. Mol. Cell 1999; 3(4):447-55.
  • Hood, J.K. and Silver, P.A. In or out? Regulating nuclear transport. Curr. Opin. Cell. Biol. 1999;11(2):241-7.
  • Valentini, S.R., Weiss, V.H., and Silver, P.A. Arginine methylation and binding of Hrp1p to the efficiency element for mRNA 3'-end formation. RNA 1999; 5(2):272-80.
  • Ferrigno, P. and Silver, P.A. Analysis of nuclear transport in vivo. Meth. Cell Biol. 1999;58:107-22.
  • Seedorf, M., Damelin, M., Kahana, J.A., Taura, T., and Silver, P.A. Interactions between a nuclear transporter and a subset of nuclear pore complex proteins depend on Ran GTPase. Mol. Cell. Biol. 1999;19(2):1547-57.


  • Hood, J.K. and Silver, P.A. Cse1p is required for export of Srp1p/importin-alpha from the nucleus in Saccharomyces cerevisiae. J. Biol. Chem. 1998; 273(52):35142-6.
  • Silberstein, S., Schlenstedt, G., Silver, P.A., and Gilmore, R. A role for the DnaJ homologue Scj1p in protein folding in the yeast endoplasmic reticulum. J. Cell. Biol. 1998;143(4):921-33.
  • Ferrigno, P., Posas, F., Koepp, D., Saito, H., and Silver, P.A. Regulated nucleo/cytoplasmic exchange of HOG1 MAPK requires the importin beta homologs NMD5 and XPO1. EMBO J. 1998;17(19):5606-14.
  • Finley et al., Unified nomenclature for subunits of the yeast proteasome regulatory particle. TIBS 1998; 23:244-245.
  • Taura, T., Krebber, H. and Silver, P.A. A member of the Ran binding protein family, Yrb2p, is involved in NES dependent nuclear protein export. Proc. Natl. Acad. Sci. USA 1998; 95:7427-7432.
  • Shen, E.C., Henry, M.F., Weiss, V.H., Valentini, S., Silver, P.A., and Lee, M.S. Arginine methylation facilitates the nuclear export of hnRNPs. Genes & Dev. 1998; 12:679-691.
  • Webb, C.D., Graumann, P., Kahana, J.A., Teleman, A., Silver, P.A. and Losick, R. Use of time-lapse microscopy to visualize rapid movement of the replication origin region of the chromosome during the cell cycle in Bacillus subtilis. Mol. Microbiol. 1998; 28:883-892.
  • Kahana, J.A., Schlenstedt, G., Geiser, J.R., Evanchuck, D.M., Hoyt, A. and Silver, P.A. The yeast dynactin complex is involved in partitioning the mitotic spindle between mother and daughter cells during anaphase B. Mol. Biol. Cell 1998; 9:1741-1756.
  • Huyett, A., Kahana, J., Silver, P., Zeng, X., and Saunders, W.S. Microtubule density controlled by antagonistic kinesin motors. J. Cell Sci. 1998; 111:295-301.
  • Vodicka, M.A., Koepp, D.M., Silver, P.A. and Emerman, M. HIV-1 Vpr interacts with the nuclear transport pathway to promote macrophage infection. Genes & Dev. 1998; 12:175-185.
  • Kahana, J. and Silver, P.A. The uses of GFP in yeast. in GFP: Green Fluorescent Protein Strategies and Applications, ed. by M. Chalfie and S. Kain; John Wiley & Sons, Inc. 1998, in press.
  • Scott, H.S., Antonarakis, S.E., Lalioti, M.D., Rossier, C., Silver, P.A., and Henry, M.F. Identification and characterization of two putative human arginine methyltransferases (HRMT1L1 and HRMT1L2). Genomics 1998; 15:330-340.
  • Koepp, D. and Silver, P.A. Nucleo-cytplasmic transport and cell proliferation. BBA Reviews in Cancer 1998; 1377:39-47.


  • Taura, T., Schlenstedt, G. and Silver, P.A. Yrb2 is a nuclear protein that interacts with Prp20p, a yeast Rcc1 homologue. J. Biol. Chem. 1997; 272:31877.
  • Kessler, Henry, M., Shen, E., Zhao, J., Gross, S., Silver, P., and Moore, C.L. Hrp1, an RNA binding protein that shuttles between the nucleus and cytoplasm, is required for mRNA 3' end formation in yeast. Genes & Dev. 1997; 11:2545-2556.
  • Lithgow, T., Cuezva, J.M., and Silver, P.A. Highways for delivery to the mitochondria. Trends in Biochemical Sciences 1997; 110-113.
  • Corbett, A.H., Koepp, D.M., and Silver, P.A. Indirect immunofluorescence in Saccharomyces cerevisiae. in Cell Biology: a Laboratory Manual ed. by David Spector; Cold Spring Harbor Press, 1997.
  • Silver, P.A. Scj1p. in Guidebook to Molecular Chaperones and Protein Folding Catalysts, ed. by M.-J. Gething; Sambrook & Tooze at Oxford University Press, 1997.
  • Corbett, A. and Silver, P. Genetic analysis of nuclear transport. Microbiology and Molecular Biology Reviews 1997; 61:193-211.
  • Lee, M. and Silver, P.A. RNA movement from the nucleus. Current Opinion in Genetics & Development 1997; 212-219.
  • Seedorf, M. and Silver, P. A. Importin/Karyopherin protein family members required for mRNA export from the nucleus. Proc. Natl. Acad. Sci. USA 1997; 94:8590-8595.
  • Clarkson, W.D., Corbett, A.H., Paschal, B.M., Kent, H.K., McCoy, A.J., Gerace, l., Silver, P.A., Stewart, M. Nuclear protein import is descreased by engineered mutants of nuclear transport factor 2 (NTF2) that do not bind GDP-Ran. J. Mol. Biol. 1997; 272:716-730.
  • Campbell, K.S., Mullane, K., Aksoy, I., Pipas, J.M., Silver, P.A., Roberts, T.M., Schaffhausen, B.S., and DeCaprio, J.A. The J-domain of SV40 large TAg mediates Hsc70 binding and viral DNA replication. Genes & Dev. 1997; 11:1098-1110.
  • Wong, D.H., Corbett, A.H., Kent, H., Stewart, M. and Silver, P.A. Interaction between the small GTPase Ran/Gsp1 and Ntf2 is required for nuclear import. Mol. Cell Biol. 1997; 17:3755-3767.


  • Kahana, J. and Silver, P. Use of the A. victoria green fluorescent protein to study protein dynamics in vivo. Current Protocols in Molecular Biology 1996; 9.7.22-9.7.28.
  • Koepp, D. and Silver, P. A GTPase that controls nuclear trafficking: Running the right way or walking RANdomly? Cell 1996; 87:1-20.
  • Corbett, A., Ferrigno, P., Henry, M., Kahana, J., Koepp, D., Lee, M., Nguyen, L., Schlenstedt, G., Seedorf, M., Shen, E., Taura, T. and Silver, P. Genetic analysis of macromolecular transport across the nuclear envelope. (Proceedings from the Nobel Symposium) Exp. Cell Res. 1996; 229:212-216.
  • Koepp, D.M., Wong, D.H., Corbett, A.H., and Silver, P.A. Dynamic localization of the nuclear import receptor and its interactions with transport factors. J. Cell Biol. 1996; 6:1163-1176.
  • DeHoratius, C. and Silver, P.A. Nuclear transport defects and nuclear envelope alterations are associated with mutation of the Saccharomyces cerevisiae NPL4 gene. Mol. Biol. Cell 1996; 7:1835-1855.
  • Henry, M. and Silver, P. A novel arginine methyltransferase (HMT1) modifies a poly(A) RNA-binding protein. Mol. Cell. Biol. 1996; 16:3668-3678.
  • Haarer, K., Corbett, A.H., Kweon, Y., Petzold, A.S., Silver, P.A. and Brown, S.S. SEC3 mutations are synthetically lethal with profilin mutations and cause defects in diploid-specific bud-site selection. Genetics 1996; 144:495-510.
  • Corbett, A.H. and Silver, P. A. The NTF2 gene encodes an essential highly conserved protein that functions in nuclear transport in vivo. J. Biol. Chem. 1996; 271:18477-18484.
  • Lee, M., Henry, M., and Silver, P. A protein that shuttles between the nucleus and the cytoplasm is an important mediator of RNA export. Genes & Dev. 1996; 10:1233-1246.
  • Henry, M., Borland, C., Bossie, M. and Silver, P. Potential RNA binding proteins in Saccharomyces cerevisiae identified as suppressors of temperature-sensitive mutations in NPL3. Genetics 1996; 142:103-115.
  • 1995
  • Koepp, D.M. and Silver, P. Rna1p, a GTPase activating protein, plays a direct role in nuclear transport. J. NIH Research 1995; 7:53-54.
  • Schlenstedt, G., Wong, D., Koepp, D. and Silver, P. Mutants in a yeast Ran binding protein are defective in nuclear transport. EMBO J. 1995; 21:5367-5378.
  • Corbett, A., Koepp, D., Schlenstedt, G., Lee, M., Hopper, A., and Silver, P. Rna1p, a Ran/TC4 GTP-activating protein, is required for nuclear import. J. Cell Biol. 1995; 130:1-10.
  • Kahana, J., Schnapp, B. and Silver, P. Kinetics of spindle pole body separation in budding yeast. Proc. Natl. Acad. Sci. USA 1995; 92:9707-9711.
  • Loeb, J.D.J., Schlenstedt, G., Pellman, D., Kornitzer, D., Silver, P.A. and Fink, G.R. A yeast nuclear import receptor homologue required for mitosis. Proc. Natl. Acad. Sci. USA 1995; 92:7647-7651.
  • Schlenstedt, G., Harris, S., Risse, B., Lill, R. and Silver, P. A yeast DnaJ homologue, Scj1, can function in the endoplasmic reticulum with BiP/Kar2p via a conserved domain that specifies interaction with Hsp70s. J. Cell Biol. 1995; 129:979-988.
  • Schlenstedt, G., Saavedra, C., Loeb, J., Cole, C. and Silver, P. The GTP-bound form of the yeast Ran/TC4 homologue blocks bi-directional transport across the nuclear envelope. Proc. Natl. Acad. Sci. USA 1995; 92:225-229.


  • Flach, J., Bossie, M., Vogel, J., Corbett, A., Jinks, T., Willins, D., and Silver, P.A. A yeast RNA binding protein shuttles between the nucleus and the cytoplasm. Mol. Cell Biol. 1994; 14:8399-407.
  • Osborne, M. A., Schlenstedt, G. Jinks, T. and Silver, P. Nuf2, a spindle pole body associated protein required for nuclear division in yeast. J. Cell Biology 1994; 125:853-66.


  • Osborne, M. and Silver, P. Nucleocytoplasmic transport in the yeast Saccharomyces cerevisiae. Annual Review of Biochemistry 1993; 62:219-54.
  • Silver, P. and Way, J. Eukarytotic DnaJ homologues and the specificity of hsp70 action. Cell 1993; 74:1-3.
  • Schlenstedt, G. , Hurt, E., Doye, V. and Silver, P. Reconstitution of nuclear protein transport with semi-intact yeast cells. J. Cell Biology 1993; 123:785-98.
  • Kurihara, T. and Silver, P. Suppression of a sec63 mutation identifies a novel component of the ER translocation apparatus. Mol. Biol. Cell 1993; 4:919-30.
  • Nelson, M., Kurihara, T. and Silver, P. Extragenic suppressors of mutations in the cytoplasmic C-terminus of Sec63 define five genes in S. cerevisiae. Genetics 1993; 134:159-73.
  • Stochaj, U., Bossie, M., van Zee, K. and Silver, P. Analysis of conserved binding proteins for nuclear localization sequences. J. Cell Science 1993; 104:89-95.


  • Kurihara, T. and Silver, P. DnaJ homologs and protein transport. in Membrane Biogenesis and Protein Targeting, ed. W. Neupert and R. Lill; Elsevier Science Publishers, 1992; 309-27.
  • Bossie, M., Barcelo, G., Dehoratius, C., and Silver, P. A mutant nuclear protein with similarity to RNA binding proteins interferes with nuclear import in yeast. Mol. Biol. Cell 1992; 3:875-93.
  • Stochaj, U. and Silver, P. A conserved phosphoprotein that specfically binds nuclear localization sequences is involved in nuclear import. J. Cell Biology 1992; 117:473-82.


  • Silver, P. How proteins enter the nucleus. Cell 1991; 64:489-97.
  • Blumberg, H. and Silver, P. A yeast protein containing two separated zinc fingers is required for normal cell growth. Gene 1991; 107:101-10.
  • Stochaj, U., Osborne, M., Kurihara, T. and Silver, P. A yeast protein that binds nuclear localization sequences: Purification, localization and antibody inhibition of binding activity. J. Cell Biology 1991; 113:1243-54.
  • Blumberg, H. and Silver, P. SCJ1, a DNAJ homologue that alters protein sorting in yeast. Nature 1991; 349:627-30.