Roberts:Publications

Home        People        Publications        Research        Presentations        Courses        News        Internal        ICE   

Peer-Reviewed Publications 2012 Kolewe ME, Roberts SC, and Henson MA. (2012) A population balance equation model of aggregation dynamics in Taxus suspension cell cultures. Biotechnology and Bioengineering 109, 472-482. PubMed Patil RA, Kolewe ME, Normanly J, Walker EL, and Roberts SC. (2012) Contribution of taxane biosynthetic pathway gene expression to observed variability in paclitaxel accumulation in Taxus suspension cultures. Biotechnology Journal 7, 418-427. PubMed Wilson SA and Roberts SC. (2012) Recent advances towards development and commercialization of plant cell culture processes for the synthesis of biomolecules. Plant Biotechnology Journal 10, 249-268. PubMed 2011 Choudhary S, White JC, Stoppel WL, Roberts SC, and Bhatia SR. (2011) Gelation behavior of polysaccharide-based interpenetrating polymer network (IPN) hydrogels. Rheologica Acta 50, 1-14. SpringerLink Gaurav V and Roberts SC. (2011) Statistical optimization of single-cell production from Taxus cuspidata plant cell aggregates. Preparative Biochemistry and Biotechnology 41, 219-35. PubMed Kolewe ME, Henson MA, and Roberts SC. (2011) Analysis of Aggregate Size as a Process Variable Affecting Paclitaxel Accumulation in Taxus Suspension Cultures. Biotechnology Progress 27, 1365–1372. PubMed Stoppel WL, White JC, Horava SD, Bhatia SR, and Roberts SC. (2011) Transport of biological molecules in surfactant-alginate composite hydrogels. Acta Biomaterialia 7, 3988-3998. PubMed 2010 Kolewe ME, Henson MA, and Roberts SC. (2010) Characterization of aggregate size in Taxus suspension cell culture. Plant Cell Reports 29, 485-494. PubMed Roberts S and Kolewe ME. (2010) Plant natural products from cultured multipotent cells. Nature Biotechnology 28, 1175-1176. Nature Biotechnology 2008 Chin K, Khattak SF, Bhatia SR, and Roberts SC. (2008) Hydrogel Perfluorocarbon Composite Scaffold Promotes Oxygen Transport to Immobilized Cells. Biotechnology progress 24, 358-366. PubMed Kolewe ME, Gaurav V, and Roberts SC. (2008) Pharmaceutically active natural product synthesis and supply via plant cell culture technology. Molecular Pharmaceutics 5, 243-256. PubMed McEntee MKE, Bhatia SK, Tao L, Roberts SC, and Bhatia SR. (2008) Tunable transport of glucose through ionically crosslinked alginate gels: Effect of alginate and calcium concentration. Journal of Applied Polymer Science 107, 2956-2962. 2007 Khattak SF, Chin K, Bhatia SR, and Roberts SC. (2007) Enhancing oxygen tension and cellular function in alginate cell encapsulation devices through the use of perfluorocarbons. Biotechnology and Bioengineering 96, 156-166. PubMed Roberts SC. (2007) Production and engineering of terpenoids in plant cell culture. Nature Chemical Biology 3, 387-395. PubMed Vongpaseuth K, Nims E, Amand MS, Walker EL, and Roberts SC. (2007) Development of a particle bombardment-mediated transient transformation system for Taxus spp. cells in culture. Biotechnology Progress 23, 1180-1185. PubMed Vongpaseuth K, and Roberts SC. (2007) Advancements in the understanding of paclitaxel metabolism in tissue culture. Current Pharmaceutical Biotechnology 8, 219-236. PubMed 2006 Khattak, S.F., Spatara, M., Roberts, L. and Roberts, S.C. (2006) Application of colorimetric assays to assess viability, growth and metabolism of hydrogel-encapsulated cells. Biotechnology letters 28, 1361-1370. PubMed Nims, E., Dubois, C.P., Roberts, S.C. and Walker, E.L. (2006) Expression profiling of genes involved in paclitaxel biosynthesis for targeted metabolic engineering. Metabolic Engineering 8, 385-394. PubMed 2005 Bhatia SR, Khattak SF, and Roberts SC. (2005) Polyelectrolytes for cell encapsulation. Current opinion in colloid & interface science 10, 45-51. ScienceDirect Khattak SF, Bhatia SR, and Roberts SC. (2005) Pluronic F127 as a cell encapsulation material: utilization of membrane-stabilizing agents. Tissue Engineering 11, 974-983. PubMed Naill MC and Roberts SC. (2005) Culture of isolated single cells from Taxus suspensions for the propagation of superior cell populations. Biotechnology Letters 27, 1725-1730. PubMed Naill MC and Roberts SC. (2005) Cell cycle analysis of Taxus suspension cultures at the single cell level as an indicator of culture heterogeneity. Biotechnology and Bioengineering 90, 491-500. PubMed Naill MC and Roberts SC. (2005) Flow cytometric analysis of protein content in Taxus protoplasts and single cells as compared to aggregated suspension cultures. Plant Cell Reports 23, 528-533. PubMed Naill MC and Roberts SC. (2005) Flow cytometric identification of paclitaxel-accumulating subpopulations. Biotechnology Progress 21, 978-983. PubMed Roberts SC. (2005) A successful introduction to chemical engineering first-semester course focusing on connection, communication and preparation. Chemical Engineering Education Summer 2005, 222-227. ChE Education 2004 Naill MC and Roberts SC. (2004) Preparation of single cells from aggregated Taxus suspension cultures for population analysis. Biotechnology and Bioengineering 86, 817-826. PubMed 2003 McAuliffe G, Roberts LA, and Roberts SC. (2003) Paclitaxel administration and its effects on clinically relelvant human cancer and noncancer cell lines. Biotechnology Letters 24, 959-964. Roberts SC, Naill M, Gibson DM, and Shuler ML. (2003) A simple method for enhancing paclitaxel release from Taxus canadensis cell suspension cultures utilizing cell wall digesting enzymes. Plant Cell Reports 21, 1217-1220. PubMed 2002 Matthew JE, Nazario YL, Roberts SC and Bhatia SR. (2002) Effect of mammalian cell culture medium on the gelation properties of Pluronic® F127. Biomaterials 23, 4615-4619. PubMed McAuliffe G, Roberts L, and Roberts SC. (2002) Paclitaxel administration and its effects on clinically relevant human cancer and non cancer cell lines. Biotechnology Letters 24, 959-964. 2001 and Older Roberts, S.G. and Shuler, M.L. (1997) Large-scale plant cell culture. Current Opinion in Biotechnology 8, 154-159. PubMed Srinivasan V, Roberts SC, and Shuler ML. (1997) Combined use of six-well polystyrene plates and thin layer chromatography for rapid development of optimal plant cell culture processes: application to taxane production byTaxus sp. Plant Cell Reports 16, 600-604. Pestchanker LJ, Roberts SC, and Shuler ML. (1996) Kinetics of taxol production and nutrient use in suspension cultures of Taxus cuspidata in shake flasks and a Wilson-type bioreactor. Enzyme and Microbial Technology 19, 256-260. Srinivasan V, Pestchanker L, Moser S, Hirasuna TJ, Taticek RA, and Shuler ML. (1995) Taxol production in bioreactors: kinetics of biomass accumulation, nutrient uptake, and taxol production by cell suspensions of Taxus baccata. Biotechnology and Bioengineering 47, 666-676. Book Chapters Patil RA and Roberts SC. (2011) Implications of cellular heterogeneity on plant cell culture performance. In: Biotechnology for Medicinal Plants, Chandra S, Lata H, and Varma A, Eds. Springer, submitted October 2011. Stoppel WL and Roberts SC. (2011) Oxygen Supply in Tissue Engineering. In: Engineering Biomaterials for Regenerative Medicine: Novel Technologies for Clinical Applications, Bhatia SK, Ed. Springer, 41-88. Springer Gaurav V, Kolewe ME, and Roberts SC. (2010) Flow Cytometric Methods to Investigate Culture Heterogeneities for Plant Metabolic Engineering. In: Plant Secondary Metabolism Engineering, Fett-Neto AGG, Ed. In: Methods in Molecular Medicine 643 Humana Press, 243-262. PubMed Roberts SC and Shuler M. (1998) Strategies for Bioproduct Optimization in Plant Cell Tissue Cultures. In: BioHydrogen, Zaborsky E, Ed. Plenum Press, New York, 483-492. Springer

http://openwetware.org/images/3/35/04_ISupportOWW.png