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Antiswitch-mediated regulation of gene expression. Antiswitch molecules are in an ‘off’ conformation (back right) when not bound to a small molecule ligand (green) and switch to an ‘on’ conformation upon ligand binding (middle left). In the ‘on’ conformation these molecules will bind to a target transcript (blue) to inhibit gene expression through antisense mechanisms (foreground).

Welcome to the Rice Lab!

This is the homepage for the laboratory of Sarah Rice, Ph.D. of the Department of Cell and Molecular Biology at Northwestern University.

Graduate students in the Rice Lab enter through the Integrated Graduate Program in the Life Sciences or the Interdepartmental Biological Sciences Graduate Program. Those interested in applying as postdoctoral fellows should contact Dr. Rice directly.