Prince:Intro to Mass Spectrometry Proteomics: Difference between revisions
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(New page: {{PrinceLab}} Here are some introductory resources to the field of Mass Spectrometry Proteomics. Add more as you come across them. * [http://www.springerlink.com/content/978-1-60761-443-2...) |
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Here are some introductory resources to the field of Mass Spectrometry Proteomics. Add more as you come across them. | Here are some introductory resources to the field of Mass Spectrometry Proteomics. Add more as you come across them. | ||
* [http://www.springerlink.com/content/978-1-60761-443-2/ Proteome Bioinformatics] - book published in 2010, free pdfs available | |||
* [http://jcb.rupress.org/content/190/4/491.full.pdf+html Mass spectrometry–based proteomics in cell biology] - review by Walther & Mann | |||
* [http://www.springerlink.com/content/978-1-60761-443-2/ Proteome Bioinformatics] - book published in 2010, free pdfs available [BYU subscription]. | |||
* [http://www.springerlink.com/content/978-1-60761-976-5/ Bioinformatics for Comparative Proteomics] - book published in 2010, free pdfs available [BYU subscription]. | |||
* [http://www.springerlink.com/content/t2854lww4371m213/#section=864259&page=1 Bioinformatics for Qualitative and Quantitative Proteomics] (chapter 15 of Bioinformatics for Omics Data) | |||
* [http://www.annualreviews.org/doi/abs/10.1146/annurev-bioeng-061008-124934 Proteomics by Mass Spectrometry: Approaches, Advances, and Applications] (Yates, Ruse, and Nakorchevsky) | |||
* [http://www.ploscompbiol.org/article/info%3Adoi%2F10.1371%2Fjournal.pcbi.1002277 Vitek and Kall overview of computation mass spec proteomics] | |||
* Matlab has a series of tutorials that are useful ('''>>doc help''' then search for '''Mass Spectrometry''') | |||
===Relevant Hype=== | |||
* Yates, Ruse, and Nakorchevsky ([http://www.annualreviews.org/doi/abs/10.1146/annurev-bioeng-061008-124934 see review above]) | |||
"Mass spectrometry (MS) is the most comprehensive and versatile tool in large-scale proteomics" | |||
* [http://archive.sciencewatch.com/march-april2007/sw_march-april2007_page3.htm Interview with Matthias Mann] (2007) | |||
Q: Where do you see mass spectrometry taking the field of proteomics in the next 5 years? | |||
A: The future is now limitless … we can read out the proteome in a quantitative way, in a large-scale fashion… | |||
We not only want to know what proteins are present in a sample, but also how they're modified… | |||
Q: Are there other applications we should keep our eyes out for? | |||
A: … new field called "interaction proteomics" … see which proteins talk to which other proteins. | |||
* [http://www.annualreviews.org/doi/abs/10.1146/annurev-bioeng-061008-124934 Can Proteomics Retire the Western Blot?] (commentary by M. Mann) |
Revision as of 11:43, 16 December 2011
Here are some introductory resources to the field of Mass Spectrometry Proteomics. Add more as you come across them.
- Mass spectrometry–based proteomics in cell biology - review by Walther & Mann
- Proteome Bioinformatics - book published in 2010, free pdfs available [BYU subscription].
- Bioinformatics for Comparative Proteomics - book published in 2010, free pdfs available [BYU subscription].
- Bioinformatics for Qualitative and Quantitative Proteomics (chapter 15 of Bioinformatics for Omics Data)
- Proteomics by Mass Spectrometry: Approaches, Advances, and Applications (Yates, Ruse, and Nakorchevsky)
- Vitek and Kall overview of computation mass spec proteomics
- Matlab has a series of tutorials that are useful (>>doc help then search for Mass Spectrometry)
Relevant Hype
- Yates, Ruse, and Nakorchevsky (see review above)
"Mass spectrometry (MS) is the most comprehensive and versatile tool in large-scale proteomics"
- Interview with Matthias Mann (2007)
Q: Where do you see mass spectrometry taking the field of proteomics in the next 5 years? A: The future is now limitless … we can read out the proteome in a quantitative way, in a large-scale fashion… We not only want to know what proteins are present in a sample, but also how they're modified… Q: Are there other applications we should keep our eyes out for? A: … new field called "interaction proteomics" … see which proteins talk to which other proteins.
- Can Proteomics Retire the Western Blot? (commentary by M. Mann)