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Revision as of 10:54, 17 January 2013 by Shelly Peyton (talk | contribs) (ChemEng 590B: Tissue Engineering)

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ChemEng 220: Chemical Engineering Principles of Biological Systems

Every fall, I teach ChE 220, an introduction to cell and molecular biology and bioengineering course. This class is required for Chemical Engineering sophomores, and is a Biological Sciences GenEd.

In 290B, we cover critical basic topics in Biology that all Chemical Engineers should know, such as:

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  • Principles of DNA-RNA-protein trascription and translation
  • How amino acid sequences within proteins dictate their physical folding
  • What the extracellular matrix is, and how it supports cells and tissues in your body
  • How cells integrate extracellular signals to adhere to tissue or migrate

Most importantly, all of these biological topics are covered within the context of core Chemical Engineering quantitative methods. Students are introduced to:
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  • Diffusion
  • Thermodynamics
  • Kinetics

Class assignments include homeworks (about 6 per semester), short quizzes to cover biology reading, 3 total exams, and a small research project at the end of the class. In the research project, students have a team, and learn how to find and scrutinize current bioengineering literature, and present a recent, exciting technology to the class.

Classes are T/Th from 9:30-10:45a, room TBA for fall 2012. Course website can be found on Moodle.

ChemEng 590B: Tissue Engineering

This graduate and undergraduate co-listed class covers the newest technologies in engineering replacement tissues, discuss how cells interact with, create, and remodel the extracellular matrix in vivo, how the matrix can feedback and regulate cell behavior, and how engineers can use this information to direct cell behavior with materials systems both in vitro and in vivo.

Lectures are 50% from myself, and 50% from students. Each student researches a single tissue engineering device, technology, or high-profile researcher. They post a summary of the topic as a webpage, using Openwetware and Wikis, as well as give a brief (15min) presentation to the class. This student-driven research in Tissue Engineering will eventually form the bases of a student-developed online resource for the global community.
Assignments include these short "wiki" modules, 3 take home exams, and 1 large research project, which is done in teams. The research project is an NIH-style grant, which is a proposal of a NEW idea, not found in literature. The grant also includes the option of generating preliminary data in the lab, so all students must be lab safety trained by UMass EHS.
Classes are currently T/Th from 4-5:15p, but this is subject to change.

Course Website

Journal Clubs

Prof. Peyton leads a journal club each semester. Please contact her directly for details about joining in either of these 1 credit journal clubs.
Cell Mechanotransduction
Fridays, 10-11am, Fall Semester Only

Stem Cells and Cancer
Tuesdays, 10-11am, Spring Semester Only