Pefabloc
From OpenWetWare
Purpose
- Pefabloc is the commerzial name for AEBSF (4-(2-Aminoethyl) benzenesulfonyl fluoride hydrochloride). It is a irreversible serine protease inhibitor and inhibits proteases like chymotrypsin, kallikrein, plasmin, thrombin, and trypsin. The specificity is similar to the inhibitor PMSF, but Pefabloc is more stable, better soluble and less toxic.
- Molecular Weight: 239.69
Procurement
You can buy Pefabloc for example at Sigma.
Use
Typical usage is 0.1 - 1.0 mM.
Safety
Pefabloc should be handeld carefully.