OSDDMalaria:Arylpyrazole Series

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Aryl Pyrazole Sub-series

The OSDDMalaria pyrazole series is derived from the OSDDMalaria GSK arylpyrrole set.

ChEMBL-NTD has 18 hits in the TCAMS data set with an aryl pyrazole core. 14 with activity below 2 micromolar:

TCMDC-131674: pXC50 3D7 147.17nM ALogP 4.88/ACD LogP 4.552


Core: Synthesis