Difference between revisions of "Nachury:Research"

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(Vesicular transport to the primary cilium: basic principles)
(Vesicular transport to the primary cilium: basic principles)
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== Vesicular transport to the primary cilium: basic principles ==
 
== Vesicular transport to the primary cilium: basic principles ==
 
[[image:Cilium_Anderson.jpg|thumb|200px|left]]
 
[[image:Cilium_Anderson.jpg|thumb|200px|left]]
The primary cilium is composed of a microtubule core enclosed within a membrane sheath, the ciliary membrane, that is continuous with the plasma membrane. Despite this continuity, ciliary and plasma membranes contain distinct complements of lipids and proteins, thus making the cilium a ''bona-fide'' organelle.
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The primary cilium is composed of a microtubule core enclosed within a membrane sheath, the ciliary membrane, that is continuous with the plasma membrane. Despite this continuity, ciliary and plasma membranes contain distinct complements of lipids and proteins, thus making the cilium a ''bona-fide'' compartment exposed to the extracellular milieu. Consequently, the cilium has been compared to a "cellular antenna".
  
 
== Regulated transport to the primary cilium ==
 
== Regulated transport to the primary cilium ==

Revision as of 20:26, 10 January 2008

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Research

Vesicular transport to the primary cilium: basic principles

Cilium Anderson.jpg

The primary cilium is composed of a microtubule core enclosed within a membrane sheath, the ciliary membrane, that is continuous with the plasma membrane. Despite this continuity, ciliary and plasma membranes contain distinct complements of lipids and proteins, thus making the cilium a bona-fide compartment exposed to the extracellular milieu. Consequently, the cilium has been compared to a "cellular antenna".

Regulated transport to the primary cilium

Cilium Regulated.jpg

Discovery of novel ciliary signaling pathways

BBS Organs.jpg