Difference between revisions of "Melissa Kemp"

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'''Melissa Kemp''' (BE postdoctoral), in collaboration with Lucia Wille, John Burke, Christina Lewis
 
'''Melissa Kemp''' (BE postdoctoral), in collaboration with Lucia Wille, John Burke, Christina Lewis
  
Investigation of the signaling dynamics and cytokine responses resulting from stimulation of the T cell receptor via ligands of varying avidity. Using a systems approach, we have generated a large dataset characterizing the multivariate relationships between ligand avidity, signaling dynamics and IL-2 production in a murine T cell hybridoma line. Partial least squares regression analysis leads to a predictive model of IL-2 production in our system.
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''Investigation of the signaling dynamics and cytokine responses resulting from stimulation of the T cell receptor via ligands of varying avidity.'' Using a systems approach, we have generated a large dataset characterizing the multivariate relationships between ligand avidity, signaling dynamics and IL-2 production in a murine T cell hybridoma line. Partial least squares regression analysis leads to a predictive model of IL-2 production in our system.
 
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Revision as of 09:01, 6 December 2005

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Melissa Kemp (BE postdoctoral), in collaboration with Lucia Wille, John Burke, Christina Lewis

Investigation of the signaling dynamics and cytokine responses resulting from stimulation of the T cell receptor via ligands of varying avidity. Using a systems approach, we have generated a large dataset characterizing the multivariate relationships between ligand avidity, signaling dynamics and IL-2 production in a murine T cell hybridoma line. Partial least squares regression analysis leads to a predictive model of IL-2 production in our system.