Difference between revisions of "Mag Lab"

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[[Image:UniLiv_logo.jpg|thumb|right|University of Liverpool Logo]]
 
[[Image:Exterior view.jpg|thumb|right|Exterior view of the Bioscience Building]]
 
[[Image:Exterior view.jpg|thumb|right|Exterior view of the Bioscience Building]]
  
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* [http://www.senescence.info/ Introduction to Biogerontology]
 
* [http://www.senescence.info/ Introduction to Biogerontology]
 
* [http://www.liv.ac.uk/ The University of Liverpool]  
 
* [http://www.liv.ac.uk/ The University of Liverpool]  
* [http://www.liv.ac.uk/bio/ School of Biological Sciences]
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* [http://www.liv.ac.uk/life-sciences/ School of Life Sciences]
 
* [http://www.liv.ac.uk/study/undergraduate/ Undergraduate]
 
* [http://www.liv.ac.uk/study/undergraduate/ Undergraduate]
 
* [http://www.liv.ac.uk/gradschool/ Graduate School]
 
* [http://www.liv.ac.uk/gradschool/ Graduate School]
 
* [http://www.liv.ac.uk/study/postgraduate/finance/ Finance & Funding]
 
* [http://www.liv.ac.uk/study/postgraduate/finance/ Finance & Funding]
 
* [http://www.liv.ac.uk/study/postgraduate/gradschool/ Postgraduate School]
 
* [http://www.liv.ac.uk/study/postgraduate/gradschool/ Postgraduate School]
* [http://www.liv.ac.uk/bio/postgrad/phd/handbook/index.html Postgraduate Handbook]  
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* [http://www.liv.ac.uk/gradschool/pgrhandbook/ Postgraduate Handbook]  
  
== Bioinformatics Tools ==  
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== Infos for Students ==
 +
[[Image:ezproxy.jpg|thumb|right|EZproxy]]
 +
If you are a member of the [http://www.liv.ac.uk/ University of Liverpool] you can get off-campus access to subscription-required journals (such as [http://www.sciencemag.org/ Science], [http://www.nature.com/ Nature], [http://www.cell.com/ Cell], etc. via [http://www.liv.ac.uk/library/electron/offcampus.html/ ezproxy].
 +
 
 +
For this purpose insert ".exproxy.liv.ac.uk." right after the [http://en.wikipedia.org/wiki/Top-level_domain/ top-level domain] (for example: .com, .gov, .de, etc.) and login with you username and password (enable cookies in the browser to avoid repeating this).
 +
 
 +
== Bioinformatics/Informatics Tools/Resources ==  
 
[[Image:Programming.jpg|thumb|right|Programming Language]]
 
[[Image:Programming.jpg|thumb|right|Programming Language]]
 
* [http://genomics.senescence.info/ HAGR (Human Ageing Genomic Resources)]
 
* [http://genomics.senescence.info/ HAGR (Human Ageing Genomic Resources)]
 
* [http://genomics.senescence.info/ GeneAge]
 
* [http://genomics.senescence.info/ GeneAge]
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* [http://gendr.org/ GenDR]
 
* [http://genomics.senescence.info/species/index.html AnAge]
 
* [http://genomics.senescence.info/species/index.html AnAge]
* [http://nebc.nox.ac.uk/tools/bio-linux/bio-linux-5.0 Bio-Linux]
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* [http://ageing-map.org/ Digital Ageing Atlas]
   
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* [http://nebc.nerc.ac.uk/tools/bio-linux/bio-linux-6.0 Bio-Linux]
==People==
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* [http://www.mozilla.com/en-US/ Firefox]
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* [http://www.zotero.org/ Zotero]
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== List of Suppliers ==
 +
[[Image:Suppliers.jpg|thumb|right|Suppliers]]
 +
This is a list of useful suppliers for both the lab and office, including basic equipments from hypercentrifuges to books:
 +
* [https://software.liv.ac.uk/Downloads.aspx/ UoL software downloads]
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* [http://www.scientificlabs.eu/ Scientific Laboratory Supplies Ltd.]
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* [http://www.neb.uk.com/ New England Biolabs (UK) Ltd]
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* [http://uk.vwr.com/app/Home VWR International]
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* [http://www.greinerbioone.com/en/start/ Greiner Bio One]
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* [http://www1.qiagen.com/ QIAGEN - Sample & Assay Technologies]
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* [http://www.invitrogen.com/site/us/en/home.html/ Invitrogen.com a Provider of Essential Life Science Technologies]
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* [http://www.sigmaaldrich.com/sigma-aldrich/home.html/ Sigma Aldrich Home]
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* [http://www.bdbeurope.com/cgi-bin/bd/bdweb/eservices/content/show.bd?RootChannel=/Knowledge%20editorials/BDB%20Documents/BDB_CHOME&BV_UseBVCookie=yes&BD_SID=UWtSQzpNQT09Ojo%3D Welcome to BD Biosciences Europe]
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* [http://www.fisher.co.uk/ Fisher Scientific UK - Laboratory supplies and chemical manufacturing]
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* [http://www.sigmaaldrich.com/life-science/custom-oligos.html/ Sigma-Genosys: Custom Oligos]
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* [http://www.shef.ac.uk/medicine/research/corefacilities/genetics.html Research Core Facilities]
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* [http://www.springerprotocols.com.ezproxy.liv.ac.uk/ Springer Protocols]
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* [http://www.springerlink.com/books/ SpringerLink - Books]
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* [http://www.mrw.interscience.wiley.com.ezproxy.liv.ac.uk/emrw/9780471142720/cp/cpmb/toc Table of Contents: Current Protocols in Molecular Biology: Wiley InterScience]
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* [https://www.roche-applied-science.com/PROD_INF/index.jsp?&id=labfaqs Roche Lab FAQs]
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* [http://www.cellsignal.com/about/marketing/marketing.html Cell Signalling Marketing Material]
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* [http://www.merckmillipore.de/life-science-research/literature/c_gfib.s1O0vMAAAEjhaVumAom#Posters Merck Posters, Brochures and Catalogs]
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== People ==
 
*[[User:Daniel A. Wuttke | Daniel A. Wuttke]]
 
*[[User:Daniel A. Wuttke | Daniel A. Wuttke]]
 
*[[User:Joao Magalhaes | Joao Magalhaes]]
 
*[[User:Joao Magalhaes | Joao Magalhaes]]
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*[[User:Yang Li Yli | Yang Li]]
  
 
== Collaborations ==
 
== Collaborations ==
* [http://tulip.liv.ac.uk/portal/pls/portal/tulwwwmerge.mergepage?p_template=biomed&p_tulipproc=staff&p_params=%3Fp_func%3Dteldir%26p_hash%3DA266763%26p_url%3DBX%26p_template%3DbiomedProf. Dr. Alan Morgan, School of Biomedical Sciences]
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* [http://www.liv.ac.uk/integrative-biology/staff/brian-merry/ Dr. Brian Merry, University of Liverpool, Functional and Comparative Genomics]
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* [http://www.liv.ac.uk/physiology/research/morgan/index.htm/ Prof. Dr. Alan Morgan, University of Liverpool, School of Biomedical Sciences]
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* [http://ualr.edu/research/index.php/tang/ Assistance Prof. Dr. Fusheng Tang, University of Arkansas, Little Rock]
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* [http://www.uams.edu/metabolic/about_us/reis.asp/ Prof. Dr. Robert J. Shmookler Reis, University of Arkansas for Medical Sciences]
  
==News & Literature==
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== News & Literature ==
 
<biblio>
 
<biblio>
 +
#Paper8 [http://pubs.aina.ucalgary.ca/arctic/Arctic64-4-497.pdf The Arctic Phoenix]
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// A wonderful long-lived sea bird, which lives at the harsh conditions of the arctic, shows little signs of senescence on sudden death, despite immense metabolic rate. http://umanitoba.ca/news/blogs/blog/2012/07/03/diving-seabird-shows-good-way-to-live-then-suddenly-die/
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[http://vimeo.com/28066351 Video]
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#Paper7 pmid=17116322
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// Creation of a human longevity-associated Network from homologous of different species. The nodes are very interesting.
 
#Paper6 pmid=19829295  
 
#Paper6 pmid=19829295  
 
// First step to understand the methylation pattern of cells and how it alters in time.  
 
// First step to understand the methylation pattern of cells and how it alters in time.  
This is intersting especially for two aspects: The embryonal development & the ageing process
+
This is interesting especially for two aspects: The embryonal development and the ageing process
 
#Paper5 pmid=19801973  
 
#Paper5 pmid=19801973  
 
// [http://en.wikipedia.org/wiki/Spermidine Spermidine] is a small molecule, just a polyamine with a very simple structure: C<sub>7</sub>H<sub>19</sub>N<sub>3</sub>
 
// [http://en.wikipedia.org/wiki/Spermidine Spermidine] is a small molecule, just a polyamine with a very simple structure: C<sub>7</sub>H<sub>19</sub>N<sub>3</sub>
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<!-- Replace the PubMed ID's ("pmid=#######") below with the PubMed ID's for your publications.  You can add or remove lines as needed 19418994 -->
 
<!-- Replace the PubMed ID's ("pmid=#######") below with the PubMed ID's for your publications.  You can add or remove lines as needed 19418994 -->
 
<biblio>
 
<biblio>
#Paper1 pmid=19522730
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#Paper1 pmid=22752047
#Paper2 pmid=19189975
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#Paper2 pmid=22722495
#Paper3 pmid=19418994  
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#Paper3 pmid=22555619
#Paper4 pmid=18986374  
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#Paper4 pmid=22327899
#Paper5 pmid=18478536  
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#Paper5 pmid=22205409
#Paper6 pmid=17595413  
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#Paper6 pmid=22188222
#Paper7 pmid=17459455  
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#Paper7 pmid=22090473
#Paper8 pmid=17339640  
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#Paper8 pmid=22073188
#Paper9 pmid=16226003  
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#Paper9 pmid=21994229
#Paper10 pmid=16024513  
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#Paper10 pmid=21600302
#Paper11 pmid=15946728  
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#Paper11 pmid=21512206
#Paper12 pmid=15619467  
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#Paper12 pmid=21226956
#Paper13 pmid=15608256  
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#Paper13 pmid=21204651
#Paper14 pmid=15489061  
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#Paper14 pmid=21182853
#Paper15 pmid=15466429  
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#Paper15 pmid=21108730
#Paper16 pmid=15383309  
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#Paper16 pmid=20538013
#Paper17 pmid=15312299  
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#Paper17 pmid=20415721
#Paper18 pmid=15280050  
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#Paper18 pmid=20388091
#Paper19 pmid=15247048  
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#Paper19 pmid=19900591
#Paper20 pmid=15177050  
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#Paper20 pmid=19522730
#Paper21 pmid=12766537  
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#Paper21 pmid=19418994
#Paper22 pmid=12175477  
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#Paper22 pmid=19388489
#Paper23 pmid=12123824  
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#Paper23 pmid=19189975
#Paper24 pmid=11583109
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#Paper24 pmid=18986374
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#Paper25 pmid=18478536
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#Paper26 pmid=17595413
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#Paper27 pmid=17459455
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#Paper28 pmid=17339640
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#Paper29 pmid=16226003
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#Paper30 pmid=16132471
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#Paper31 pmid=16024513
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#Paper32 pmid=15946728
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#Paper33 pmid=15619467
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#Paper34 pmid=15608256
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#Paper35 pmid=15489061
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#Paper36 pmid=15466429
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#Paper37 pmid=15383309
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#Paper38 pmid=15312299
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#Paper39 pmid=15280050
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#Paper40 pmid=15247048
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#Paper41 pmid=15177050
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#Paper42 pmid=12766537
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#Paper43 pmid=12175477
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#Paper44 pmid=12123824
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#Paper45 pmid=11583109
 
#Book1 isbn=9780415419543  
 
#Book1 isbn=9780415419543  
 
#Book2 isbn=9780203866740
 
#Book2 isbn=9780203866740
 
</biblio>
 
</biblio>

Revision as of 08:57, 15 July 2012

University of Liverpool Logo
Exterior view of the Bioscience Building

Welcome to the lab wiki of the Integrative Genomics of Ageing Group. We are a highly interdisciplinary and international team, located in the heart of Liverpool (United Kingdom) and using in silico, in vitro as well as in vivo approaches to study the biology and genetics of ageing. The group's PI is Joao Pedro de Magalhaes, hence the name Mag Lab.

About our lab

Scientists

Useful Links For Prospective Students

Night time lapse of the Bioscience Building

Infos for Students

EZproxy

If you are a member of the University of Liverpool you can get off-campus access to subscription-required journals (such as Science, Nature, Cell, etc. via ezproxy.

For this purpose insert ".exproxy.liv.ac.uk." right after the top-level domain (for example: .com, .gov, .de, etc.) and login with you username and password (enable cookies in the browser to avoid repeating this).

Bioinformatics/Informatics Tools/Resources

Programming Language

List of Suppliers

Suppliers

This is a list of useful suppliers for both the lab and office, including basic equipments from hypercentrifuges to books:

People

Collaborations

News & Literature

  1. The Arctic Phoenix [Paper8]
    A wonderful long-lived sea bird, which lives at the harsh conditions of the arctic, shows little signs of senescence on sudden death, despite immense metabolic rate. http://umanitoba.ca/news/blogs/blog/2012/07/03/diving-seabird-shows-good-way-to-live-then-suddenly-die/

    Video

  2. Budovsky A, Abramovich A, Cohen R, Chalifa-Caspi V, and Fraifeld V. Longevity network: construction and implications. Mech Ageing Dev. 2007 Jan;128(1):117-24. DOI:10.1016/j.mad.2006.11.018 | PubMed ID:17116322 | HubMed [Paper7]
    Creation of a human longevity-associated Network from homologous of different species. The nodes are very interesting.
  3. Lister R, Pelizzola M, Dowen RH, Hawkins RD, Hon G, Tonti-Filippini J, Nery JR, Lee L, Ye Z, Ngo QM, Edsall L, Antosiewicz-Bourget J, Stewart R, Ruotti V, Millar AH, Thomson JA, Ren B, and Ecker JR. Human DNA methylomes at base resolution show widespread epigenomic differences. Nature. 2009 Nov 19;462(7271):315-22. DOI:10.1038/nature08514 | PubMed ID:19829295 | HubMed [Paper6]
    First step to understand the methylation pattern of cells and how it alters in time.

    This is interesting especially for two aspects: The embryonal development and the ageing process

  4. Eisenberg T, Knauer H, Schauer A, Büttner S, Ruckenstuhl C, Carmona-Gutierrez D, Ring J, Schroeder S, Magnes C, Antonacci L, Fussi H, Deszcz L, Hartl R, Schraml E, Criollo A, Megalou E, Weiskopf D, Laun P, Heeren G, Breitenbach M, Grubeck-Loebenstein B, Herker E, Fahrenkrog B, Fröhlich KU, Sinner F, Tavernarakis N, Minois N, Kroemer G, and Madeo F. Induction of autophagy by spermidine promotes longevity. Nat Cell Biol. 2009 Nov;11(11):1305-14. DOI:10.1038/ncb1975 | PubMed ID:19801973 | HubMed [Paper5]
    Spermidine is a small molecule, just a polyamine with a very simple structure: C7H19N3
  5. Zid BM, Rogers AN, Katewa SD, Vargas MA, Kolipinski MC, Lu TA, Benzer S, and Kapahi P. 4E-BP extends lifespan upon dietary restriction by enhancing mitochondrial activity in Drosophila. Cell. 2009 Oct 2;139(1):149-60. DOI:10.1016/j.cell.2009.07.034 | PubMed ID:19804760 | HubMed [Paper4]
    Translating Dietary Restriction into Long Life PaperFlick Supporting Documents
  6. Veatch JR, McMurray MA, Nelson ZW, and Gottschling DE. Mitochondrial dysfunction leads to nuclear genome instability via an iron-sulfur cluster defect. Cell. 2009 Jun 26;137(7):1247-58. DOI:10.1016/j.cell.2009.04.014 | PubMed ID:19563757 | HubMed [Paper3]
    Mitochondrial Links to Genomic Instability in Aging PaperFlick
  7. Brunet A. Cancer: When restriction is good. Nature. 2009 Apr 9;458(7239):713-4. DOI:10.1038/458713a | PubMed ID:19360073 | HubMed [Paper2]
    Nice essay about connections of cancer, ageing and CR
  8. Kalaany NY and Sabatini DM. Tumours with PI3K activation are resistant to dietary restriction. Nature. 2009 Apr 9;458(7239):725-31. DOI:10.1038/nature07782 | PubMed ID:19279572 | HubMed [Paper1]
    I think xenografts are a very bad model of cancer formation [DW].
All Medline abstracts: PubMed | HubMed

Publications

  1. Yu C, Li Y, Holmes A, Szafranski K, Faulkes CG, Coen CW, Buffenstein R, Platzer M, de Magalhães JP, and Church GM. RNA sequencing reveals differential expression of mitochondrial and oxidation reduction genes in the long-lived naked mole-rat when compared to mice. PLoS One. 2011;6(11):e26729. DOI:10.1371/journal.pone.0026729 | PubMed ID:22073188 | HubMed [Paper8]
  2. de Magalhães JP, Wuttke D, Wood SH, Plank M, and Vora C. Genome-environment interactions that modulate aging: powerful targets for drug discovery. Pharmacol Rev. 2012 Jan;64(1):88-101. DOI:10.1124/pr.110.004499 | PubMed ID:22090473 | HubMed [Paper7]
  3. de Magalhães JP and Matsuda A. Genome-wide patterns of genetic distances reveal candidate Loci contributing to human population-specific traits. Ann Hum Genet. 2012 Mar;76(2):142-58. DOI:10.1111/j.1469-1809.2011.00695.x | PubMed ID:22188222 | HubMed [Paper6]
  4. Li Y and de Magalhães JP. Accelerated protein evolution analysis reveals genes and pathways associated with the evolution of mammalian longevity. Age (Dordr). 2013 Apr;35(2):301-14. DOI:10.1007/s11357-011-9361-y | PubMed ID:22205409 | HubMed [Paper5]
  5. Plank M, Wuttke D, van Dam S, Clarke SA, and de Magalhães JP. A meta-analysis of caloric restriction gene expression profiles to infer common signatures and regulatory mechanisms. Mol Biosyst. 2012 Apr;8(4):1339-49. DOI:10.1039/c2mb05255e | PubMed ID:22327899 | HubMed [Paper4]
  6. Wood SH, Craig T, Li Y, Merry B, and de Magalhães JP. Whole transcriptome sequencing of the aging rat brain reveals dynamic RNA changes in the dark matter of the genome. Age (Dordr). 2013 Jun;35(3):763-76. DOI:10.1007/s11357-012-9410-1 | PubMed ID:22555619 | HubMed [Paper3]
  7. Wuttke D and de Magalhães JP. Osh6 links yeast vacuolar functions to lifespan extension and TOR. Cell Cycle. 2012 Jul 1;11(13):2419. DOI:10.4161/cc.21069 | PubMed ID:22722495 | HubMed [Paper2]
  8. Aledo JC, Valverde H, and de Magalhães JP. Mutational bias plays an important role in shaping longevity-related amino acid content in mammalian mtDNA-encoded proteins. J Mol Evol. 2012 Jun;74(5-6):332-41. DOI:10.1007/s00239-012-9510-7 | PubMed ID:22752047 | HubMed [Paper1]
  9. Silva AS, Wood SH, van Dam S, Berres S, McArdle A, and de Magalhães JP. Gathering insights on disease etiology from gene expression profiles of healthy tissues. Bioinformatics. 2011 Dec 1;27(23):3300-5. DOI:10.1093/bioinformatics/btr559 | PubMed ID:21994229 | HubMed [Paper9]
  10. Freitas AA and de Magalhães JP. A review and appraisal of the DNA damage theory of ageing. Mutat Res. 2011 Jul-Oct;728(1-2):12-22. DOI:10.1016/j.mrrev.2011.05.001 | PubMed ID:21600302 | HubMed [Paper10]
  11. de Magalhães JP. A role for Ras signaling in modulating mammalian aging by the GH/IGF1 axis. Aging (Albany NY). 2011 Apr;3(4):336-7. DOI:10.18632/aging.100309 | PubMed ID:21512206 | HubMed [Paper11]
  12. Freitas AA, Vasieva O, and de Magalhães JP. A data mining approach for classifying DNA repair genes into ageing-related or non-ageing-related. BMC Genomics. 2011 Jan 12;12:27. DOI:10.1186/1471-2164-12-27 | PubMed ID:21226956 | HubMed [Paper12]
  13. Fuellen G, Adjaye J, de Grey A, Lepperdinger G, de Magalhães JP, Sühnel J, and Wipat A. Bioinformatics in aging research: a workshop report. Rejuvenation Res. 2010 Dec;13(6):763-7. DOI:10.1089/rej.2010.1125 | PubMed ID:21204651 | HubMed [Paper13]
  14. de Magalhães JP. Paternal genome effects on aging: evidence for a role of Rasgrf1 in longevity determination?. Mech Ageing Dev. 2011 Jan-Feb;132(1-2):72-3. DOI:10.1016/j.mad.2010.11.004 | PubMed ID:21182853 | HubMed [Paper14]
  15. Aledo JC, Li Y, de Magalhães JP, Ruíz-Camacho M, and Pérez-Claros JA. Mitochondrially encoded methionine is inversely related to longevity in mammals. Aging Cell. 2011 Apr;10(2):198-207. DOI:10.1111/j.1474-9726.2010.00657.x | PubMed ID:21108730 | HubMed [Paper15]
  16. Nicholas A, de Magalhaes JP, Kraytsberg Y, Richfield EK, Levanon EY, and Khrapko K. Age-related gene-specific changes of A-to-I mRNA editing in the human brain. Mech Ageing Dev. 2010 Jun;131(6):445-7. DOI:10.1016/j.mad.2010.06.001 | PubMed ID:20538013 | HubMed [Paper16]
  17. Finch CE, Morgan TE, Longo VD, and de Magalhaes JP. Cell resilience in species life spans: a link to inflammation?. Aging Cell. 2010 Aug;9(4):519-26. DOI:10.1111/j.1474-9726.2010.00578.x | PubMed ID:20415721 | HubMed [Paper17]
  18. Cevenini E, Bellavista E, Tieri P, Castellani G, Lescai F, Francesconi M, Mishto M, Santoro A, Valensin S, Salvioli S, Capri M, Zaikin A, Monti D, de Magalhães JP, and Franceschi C. Systems biology and longevity: an emerging approach to identify innovative anti-aging targets and strategies. Curr Pharm Des. 2010;16(7):802-13. PubMed ID:20388091 | HubMed [Paper18]
  19. de Magalhães JP, Finch CE, and Janssens G. Next-generation sequencing in aging research: emerging applications, problems, pitfalls and possible solutions. Ageing Res Rev. 2010 Jul;9(3):315-23. DOI:10.1016/j.arr.2009.10.006 | PubMed ID:19900591 | HubMed [Paper19]
  20. de Magalhães JP and Costa J. A database of vertebrate longevity records and their relation to other life-history traits. J Evol Biol. 2009 Aug;22(8):1770-4. DOI:10.1111/j.1420-9101.2009.01783.x | PubMed ID:19522730 | HubMed [Paper20]
  21. de Magalhães JP. Ageing research in the post-genome era: new technologies for an old problem. SEB Exp Biol Ser. 2009;62:99-115. PubMed ID:19418994 | HubMed [Paper21]
  22. Maldonado J, Pereira T, and Estudo AMPA.. Self-measurement of blood pressure in arterial hypertension--preliminary results from the AMPA study. Rev Port Cardiol. 2009 Jan;28(1):7-21. PubMed ID:19388489 | HubMed [Paper22]
  23. de Magalhães JP, Curado J, and Church GM. Meta-analysis of age-related gene expression profiles identifies common signatures of aging. Bioinformatics. 2009 Apr 1;25(7):875-81. DOI:10.1093/bioinformatics/btp073 | PubMed ID:19189975 | HubMed [Paper23]
  24. de Magalhães JP, Budovsky A, Lehmann G, Costa J, Li Y, Fraifeld V, and Church GM. The Human Ageing Genomic Resources: online databases and tools for biogerontologists. Aging Cell. 2009 Feb;8(1):65-72. DOI:10.1111/j.1474-9726.2008.00442.x | PubMed ID:18986374 | HubMed [Paper24]
  25. de Magalhães JP and Faragher RG. Cell divisions and mammalian aging: integrative biology insights from genes that regulate longevity. Bioessays. 2008 Jun;30(6):567-78. DOI:10.1002/bies.20760 | PubMed ID:18478536 | HubMed [Paper25]
  26. de Magalhães JP, Sedivy JM, Finch CE, Austad SN, and Church GM. A proposal to sequence genomes of unique interest for research on aging. J Gerontol A Biol Sci Med Sci. 2007 Jun;62(6):583-4. PubMed ID:17595413 | HubMed [Paper26]
  27. de Magalhães JP and Church GM. Analyses of human-chimpanzee orthologous gene pairs to explore evolutionary hypotheses of aging. Mech Ageing Dev. 2007 May-Jun;128(5-6):355-64. DOI:10.1016/j.mad.2007.03.004 | PubMed ID:17459455 | HubMed [Paper27]
  28. de Magalhães JP, Costa J, and Church GM. An analysis of the relationship between metabolism, developmental schedules, and longevity using phylogenetic independent contrasts. J Gerontol A Biol Sci Med Sci. 2007 Feb;62(2):149-60. PubMed ID:17339640 | HubMed [Paper28]
  29. de Magalhães JP and Church GM. Cells discover fire: employing reactive oxygen species in development and consequences for aging. Exp Gerontol. 2006 Jan;41(1):1-10. DOI:10.1016/j.exger.2005.09.002 | PubMed ID:16226003 | HubMed [Paper29]
  30. de Magalhães JP. Human disease-associated mitochondrial mutations fixed in nonhuman primates. J Mol Evol. 2005 Oct;61(4):491-7. DOI:10.1007/s00239-004-0258-6 | PubMed ID:16132471 | HubMed [Paper30]
  31. de Magalhães JP and Church GM. Genomes optimize reproduction: aging as a consequence of the developmental program. Physiology (Bethesda). 2005 Aug;20:252-9. DOI:10.1152/physiol.00010.2005 | PubMed ID:16024513 | HubMed [Paper31]
  32. de Magalhães JP and Sandberg A. Cognitive aging as an extension of brain development: a model linking learning, brain plasticity, and neurodegeneration. Mech Ageing Dev. 2005 Oct;126(10):1026-33. DOI:10.1016/j.mad.2005.04.004 | PubMed ID:15946728 | HubMed [Paper32]
  33. de Magalhães JP. Open-minded scepticism: inferring the causal mechanisms of human ageing from genetic perturbations. Ageing Res Rev. 2005 Jan;4(1):1-22. DOI:10.1016/j.arr.2004.05.003 | PubMed ID:15619467 | HubMed [Paper33]
  34. de Magalhães JP, Costa J, and Toussaint O. HAGR: the Human Ageing Genomic Resources. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D537-43. DOI:10.1093/nar/gki017 | PubMed ID:15608256 | HubMed [Paper34]
  35. de Magalhães JP, Chainiaux F, de Longueville F, Mainfroid V, Migeot V, Marcq L, Remacle J, Salmon M, and Toussaint O. Gene expression and regulation in H2O2-induced premature senescence of human foreskin fibroblasts expressing or not telomerase. Exp Gerontol. 2004 Sep;39(9):1379-89. DOI:10.1016/j.exger.2004.06.004 | PubMed ID:15489061 | HubMed [Paper35]
  36. de Magalhães JP, Cabral JA, and Magalhães D. The influence of genes on the aging process of mice: a statistical assessment of the genetics of aging. Genetics. 2005 Jan;169(1):265-74. DOI:10.1534/genetics.104.032292 | PubMed ID:15466429 | HubMed [Paper36]
  37. de Magalhães JP. From cells to ageing: a review of models and mechanisms of cellular senescence and their impact on human ageing. Exp Cell Res. 2004 Oct 15;300(1):1-10. DOI:10.1016/j.yexcr.2004.07.006 | PubMed ID:15383309 | HubMed [Paper37]
  38. de Magalhães JP and Toussaint O. Telomeres and telomerase: a modern fountain of youth?. Rejuvenation Res. 2004 Summer;7(2):126-33. DOI:10.1089/1549168041553044 | PubMed ID:15312299 | HubMed [Paper38]
  39. de Magalhães JP and Toussaint O. GenAge: a genomic and proteomic network map of human ageing. FEBS Lett. 2004 Jul 30;571(1-3):243-7. DOI:10.1016/j.febslet.2004.07.006 | PubMed ID:15280050 | HubMed [Paper39]
  40. de Magalhães JP, Migeot V, Mainfroid V, de Longueville F, Remacle J, and Toussaint O. No increase in senescence-associated beta-galactosidase activity in Werner syndrome fibroblasts after exposure to H2O2. Ann N Y Acad Sci. 2004 Jun;1019:375-8. DOI:10.1196/annals.1297.066 | PubMed ID:15247048 | HubMed [Paper40]
  41. de Magalhães JP and Toussaint O. How bioinformatics can help reverse engineer human aging. Ageing Res Rev. 2004 Apr;3(2):125-41. DOI:10.1016/j.arr.2003.08.006 | PubMed ID:15177050 | HubMed [Paper41]
  42. de Magalhães JP. Is mammalian aging genetically controlled?. Biogerontology. 2003;4(2):119-20. PubMed ID:12766537 | HubMed [Paper42]
  43. de Magalhães JP and Toussaint O. The evolution of mammalian aging. Exp Gerontol. 2002 Jun;37(6):769-75. PubMed ID:12175477 | HubMed [Paper43]
  44. de Magalhães JP, Chainiaux F, Remacle J, and Toussaint O. Stress-induced premature senescence in BJ and hTERT-BJ1 human foreskin fibroblasts. FEBS Lett. 2002 Jul 17;523(1-3):157-62. PubMed ID:12123824 | HubMed [Paper44]
  45. Dumont P, Royer V, Pascal T, Dierick JF, Chainiaux F, Frippiat C, de Magalhaes JP, Eliaers F, Remacle J, and Toussaint O. Growth kinetics rather than stress accelerate telomere shortening in cultures of human diploid fibroblasts in oxidative stress-induced premature senescence. FEBS Lett. 2001 Aug 3;502(3):109-12. PubMed ID:11583109 | HubMed [Paper45]
  46. edited by Christine Foyer, Richard Faragher, Paul Thornalley. Redox metabolism and longevity relationships in animals and plants. New York, NY: Taylor & Francis Group, 2009. ISBN:9780415419543 [Book1]
  47. ISBN:9780203866740 [Book2]
All Medline abstracts: PubMed | HubMed