Difference between revisions of "Luo Lab:Research"

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==Overview==
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<div style="padding: 10px; width: 720px">
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==About==
  
<pre>
 
 
Interactions between cells and extracellular matrix (ECM) play pivotal roles in directing  
 
Interactions between cells and extracellular matrix (ECM) play pivotal roles in directing  
 
cellular and tissue functions.  However, due to the ultra complexity of biological systems,  
 
cellular and tissue functions.  However, due to the ultra complexity of biological systems,  
 
our current understanding of cell-ECM processes and our capability to control the relevant  
 
our current understanding of cell-ECM processes and our capability to control the relevant  
 
events have been rather limited.  By integrating our knowledge in material science and  
 
events have been rather limited.  By integrating our knowledge in material science and  
engineering, microfabrication and biology, our research is aimed at designing engineered  
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engineering, microfabrication and biology, our research is aimed at generating engineered  
extracellular microenvironment for understanding and controlling cell behavior.  This work
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extracellular microenvironment for understanding and controlling cell behavior.  Experiments
can facilitate the analysis and identification of essential extracellular cues, which can  
+
are designed to facilitate the analysis and identification of essential extracellular cues,  
be further applied to 2-D and 3-D artificial systems to monitor, trigger or modulate biological  
+
which can be further applied to 2-D and 3-D artificial systems to monitor, trigger or modulate
processes.  On one application front, our materials and devices are geared toward controlling
+
biological processes.  On one application front, our materials and devices are geared toward  
stem cell fate and directing stem cell differentiation for use of regenerative medicine.
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controlling stem cell fate and directing stem cell differentiation for use of regenerative  
On another application front, it is our interest to build targeted and triggerable delivery  
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medicine. On another application front, it is our interest to build targeted and triggerable  
systems for therapeutic compounds/cells to improve treatment outcomes.  
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delivery systems for therapeutic compounds/cells to improve treatment outcomes.  
  
</pre>
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==Projects==
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Stay tuned!

Latest revision as of 20:46, 22 November 2008

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About

Interactions between cells and extracellular matrix (ECM) play pivotal roles in directing cellular and tissue functions. However, due to the ultra complexity of biological systems, our current understanding of cell-ECM processes and our capability to control the relevant events have been rather limited. By integrating our knowledge in material science and engineering, microfabrication and biology, our research is aimed at generating engineered extracellular microenvironment for understanding and controlling cell behavior. Experiments are designed to facilitate the analysis and identification of essential extracellular cues, which can be further applied to 2-D and 3-D artificial systems to monitor, trigger or modulate biological processes. On one application front, our materials and devices are geared toward controlling stem cell fate and directing stem cell differentiation for use of regenerative medicine. On another application front, it is our interest to build targeted and triggerable delivery systems for therapeutic compounds/cells to improve treatment outcomes.


Projects

Stay tuned!