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  1. Lee W, Patel JH, and Lockhart AC. Novel targets in esophageal and gastric cancer: beyond antiangiogenesis. Expert Opin Investig Drugs. 2009 Sep;18(9):1351-64. DOI:10.1517/13543780903179286 | PubMed ID:19642951 | HubMed [1]


  1. Lee W, Belkhiri A, Lockhart AC, Merchant N, Glaeser H, Harris EI, Washington MK, Brunt EM, Zaika A, Kim RB, and El-Rifai W. Overexpression of OATP1B3 confers apoptotic resistance in colon cancer. Cancer Res. 2008 Dec 15;68(24):10315-23. DOI:10.1158/0008-5472.CAN-08-1984 | PubMed ID:19074900 | HubMed [1]
  2. Lockhart AC, Harris E, LaFleur BJ, Merchant NB, Washington MK, Resnick MB, Yeatman TJ, Lee W. Organic anion transporting polypeptide 1B3 (OATP1B3) is overexpressed in colorectal tumors and is a predictor of clinical outcome. Clin Exp Gastroenterol:1-7(2008) [2]
  3. Wade Calcutt M, Lee W, Puzanov I, Rothenberg ML, and Hachey DL. Determination of chemically reduced pyrrolobenzodiazepine SJG-136 in human plasma by HPLC-MS/MS: application to an anticancer phase I dose escalation study. J Mass Spectrom. 2008 Jan;43(1):42-52. DOI:10.1002/jms.1268 | PubMed ID:17683023 | HubMed [3]
All Medline abstracts: PubMed | HubMed


  1. Glaeser H, Bailey DG, Dresser GK, Gregor JC, Schwarz UI, McGrath JS, Jolicoeur E, Lee W, Leake BF, Tirona RG, and Kim RB. Intestinal drug transporter expression and the impact of grapefruit juice in humans. Clin Pharmacol Ther. 2007 Mar;81(3):362-70. DOI:10.1038/sj.clpt.6100056 | PubMed ID:17215845 | HubMed [1]
  2. Marzolini C, Tirona RG, Gervasini G, Poonkuzhali B, Assem M, Lee W, Leake BF, Schuetz JD, Schuetz EG, and Kim RB. A common polymorphism in the bile acid receptor farnesoid X receptor is associated with decreased hepatic target gene expression. Mol Endocrinol. 2007 Aug;21(8):1769-80. DOI:10.1210/me.2007-0025 | PubMed ID:17519356 | HubMed [2]
  3. Ho RH, Choi L, Lee W, Mayo G, Schwarz UI, Tirona RG, Bailey DG, Stein CM, and Kim RB. Effect of drug transporter genotypes on pravastatin disposition in European- and African-American participants. Pharmacogenet Genomics. 2007 Aug;17(8):647-56. DOI:10.1097/FPC.0b013e3280ef698f | PubMed ID:17622941 | HubMed [3]
All Medline abstracts: PubMed | HubMed


  1. Ho RH, Tirona RG, Leake BF, Glaeser H, Lee W, Lemke CJ, Wang Y, and Kim RB. Drug and bile acid transporters in rosuvastatin hepatic uptake: function, expression, and pharmacogenetics. Gastroenterology. 2006 May;130(6):1793-806. DOI:10.1053/j.gastro.2006.02.034 | PubMed ID:16697742 | HubMed [1]
  2. Lee W, Glaeser H, Smith LH, Roberts RL, Moeckel GW, Gervasini G, Leake BF, and Kim RB. Polymorphisms in human organic anion-transporting polypeptide 1A2 (OATP1A2): implications for altered drug disposition and central nervous system drug entry. J Biol Chem. 2005 Mar 11;280(10):9610-7. DOI:10.1074/jbc.M411092200 | PubMed ID:15632119 | HubMed [2]
  3. Lee W, Lockhart AC, Kim RB, and Rothenberg ML. Cancer pharmacogenomics: powerful tools in cancer chemotherapy and drug development. Oncologist. 2005 Feb;10(2):104-11. DOI:10.1634/theoncologist.10-2-104 | PubMed ID:15709212 | HubMed [3]
  4. Sandhu P, Lee W, Xu X, Leake BF, Yamazaki M, Stone JA, Lin JH, Pearson PG, and Kim RB. Hepatic uptake of the novel antifungal agent caspofungin. Drug Metab Dispos. 2005 May;33(5):676-82. DOI:10.1124/dmd.104.003244 | PubMed ID:15716364 | HubMed [4]
  5. Lee W and Kim RB. Transporters and renal drug elimination. Annu Rev Pharmacol Toxicol. 2004;44:137-66. DOI:10.1146/annurev.pharmtox.44.101802.121856 | PubMed ID:14744242 | HubMed [5]
  6. Ho RH, Leake BF, Roberts RL, Lee W, and Kim RB. Ethnicity-dependent polymorphism in Na+-taurocholate cotransporting polypeptide (SLC10A1) reveals a domain critical for bile acid substrate recognition. J Biol Chem. 2004 Feb 20;279(8):7213-22. DOI:10.1074/jbc.M305782200 | PubMed ID:14660639 | HubMed [6]
  7. Tirona RG, Lee W, Leake BF, Lan LB, Cline CB, Lamba V, Parviz F, Duncan SA, Inoue Y, Gonzalez FJ, Schuetz EG, and Kim RB. The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4. Nat Med. 2003 Feb;9(2):220-4. DOI:10.1038/nm815 | PubMed ID:12514743 | HubMed [7]
  8. Lee WI and Fung HL. Mechanism-based partial inactivation of glutathione S-transferases by nitroglycerin: tyrosine nitration vs sulfhydryl oxidation. Nitric Oxide. 2003 Mar;8(2):103-10. PubMed ID:12620373 | HubMed [8]
  9. Lee WI, Xu Y, Fung SM, and Fung HL. eNOS-dependent vascular interaction between nitric oxide and calcitonin gene-related peptide in mice: gender selectivity and effects on blood aggregation. Regul Pept. 2003 Jan 31;110(2):115-22. PubMed ID:12527144 | HubMed [9]
  10. Wang EQ, Lee WI, Brazeau D, and Fung HL. cDNA microarray analysis of vascular gene expression after nitric oxide donor infusions in rats: implications for nitrate tolerance mechanisms. AAPS PharmSci. 2002;4(2):E10. DOI:10.1208/ps040210 | PubMed ID:12102619 | HubMed [10]
  11. Wang EQ, Lee WI, and Fung HL. Lack of critical involvement of endothelial nitric oxide synthase in vascular nitrate tolerance in mice. Br J Pharmacol. 2002 Jan;135(2):299-302. DOI:10.1038/sj.bjp.0704532 | PubMed ID:11815364 | HubMed [11]
  12. Tabrizi-Fard MA, Lee WI, and Fung HL. Differential interactions of nitric oxide donors with rat oxyhemoglobin. Biochem Pharmacol. 1999 Aug 15;58(4):671-4. PubMed ID:10413305 | HubMed [12]
All Medline abstracts: PubMed | HubMed