Difference between revisions of "LabName:Alcazar"

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**** New lab webpage hosted at University of Barcelona servers***
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Please visit: http://www.ub.edu/portal/web/dp-bsma/stress
  
 
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{{Template:Alcazar Vertical Menu}}
 
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'''''Dear visitor,'''''<br>
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<br> Welcome to the Molecular Genetics of Plant Stress Tolerance Lab (Ruben Alcazar & A.F. Tiburcio Labs) ''' at the Department of Biology, Healthcare & Environment of the University of Barcelona. <br><br>
 +
We're a recently created joint research group that investigates the '''adaptation of plants to local environments'''. We focus on the evolutionary adaptation of plant populations to '''abiotic and biotic stresses''', which are major challenges for plant survival under the current climate change predictions. Derived from our research, we investigate ways for improving stress protection.<br>
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<font face="calibri" style="color:#000000" font size="4"><br>
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For a more detailed view of our research, please have a look at our [http://alcazar.openwetware.org/Research.html Research Projects] and [http://alcazar.openwetware.org/Publications.html Scientific Publications] sections. You can follow an updated list of our activities and publications in the NEWS section below. For any other enquires, do not hesitate to contact us directly.<br><br>
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<br><br><br><br><br><br><br><br>
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----
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<br>
 
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'''''Plant-Environment Interactions'''''
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'''1. POLYAMINE PERCEPTION AND SIGNALING'''
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<div id="right menu" style="width:275px; padding: 1em 2em; float:left;">
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[[Image:Polyamines.jpg|300px]]
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<br>
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<font face="calibri" style="color:#000000" font size="4">
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Our research laboratory has long-standing experience in the field of plant polyamines, for which we performed a number of omics approaches and established genetic evidence for their role in abiotic stress protection.
 +
 
 +
 
 +
Our previous research pointed to interactions of polyamines with hormones and other stress-related metabolites. Our current goal is to investigate how polyamines are perceived by the plant, which early signaling components are involved, and how this is shaped by the environment.
 +
 
 +
 
 +
We’re making use of background knowledge from different disciplines to gain insight into polyamine perception and signaling, for which little is known in plants. We’re making use of genetics of natural variation, reverse genetics, molecular biology and plant-microbe interactions to unravel how polyamines are sensed and how this relates to the local microbiota.
 +
 
 +
 
 +
Our final goal is to provide novel approaches for crop protection against abiotic and biotic stresses.
 +
 
  
 +
Key words: stress tolerance, drought, salinity, freezing tolerance, priming, ROS, crop protection, microbiome, rhizosphere, polyamines, natural variation, transcriptional regulation, metabolon, modulon.
 +
 +
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'''2. MOLECULAR EVOLUTION OF DISEASE RESISTANCE IN PLANTS''' <br>
 
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We're interested in genetics of natural variation, population genetics and molecular biology. We want to know how climate change is shaping plant's resistance and tolerance traits under a combined multidisciplinary approach. Our lab undertakes a research approach that looks for the genetic and molecular basis of naturally occurring quantitative variation in biotic and abiotic stress responses, and how these interact with the environment (genotype-by-environment interactions). This multidisciplinary approach will allow a better understanding of the natural evolution of stress pathways in plants and efficient know-how transfer to practical applications.<br>
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In our lab, we make use of the extensive natural variation of [https://en.wikipedia.org/wiki/Arabidopsis_thaliana ''Arabidopsis thaliana''] populations to answer key fundamental questions:
 +
 
 +
* '''How plants adapt to local environments including the microbiota?'''
 +
* '''How plants maintain variability of genes involved in pathogen recognition and to which extent this variability is caused by the interaction with pathogens?'''
 +
* '''How the environment manipulates immune responses? How this affects the above points?'''
 +
 
 +
 
 +
To address these and other questions, we (and others) developed a new model for plant immunity studies based on the use of ''Arabidopsis'' immune-related incompatible hybrids. These are hybrids obtained by crosses of natural ''Arabidopsis'' accessions that exhibit constitutive activation of defense, stunted growth and sterility in the absence of pathogen challenge. Often, such phenotypes are temperature-dependent and suppressed at high temperature.
 +
 
 +
 
 +
These genetic interactions might unravel molecular partners required for proper modulation of defense. Some of these cases are background-dependent and therefore, likely difficult to be observed in classical reference accessions.
 +
 
 +
 
 +
Since some years, we're using the Ler / Kas-2 immune-related hybrid incompatibility as molecular model to answer some of the questions above. The Landsberg (from Gorzów Wielkopolski, Poland)/Kashmir-2 (from Kashmir mountains) incompatibility involves populations in Central Europe and Central Asia which enable to expand our analyses to population scales. We apply population genetics on top of our molecular and biochemical analyses.  
  
  
For a more detailed view of our research plans, please have a look at our [http://openwetware.org/wiki/Alcazar:Research Research Projects] and [http://openwetware.org/wiki/Alcazar:Publications Scientific Publications] sections.
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Derived from our research, we attempt to provide new strategies for crop protection at medium to long-term.  
<br><br>
 
<br><br>
 
  
  
 
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'''LATEST NEWS'''
 
<font face="calibri" style="color:#000000" font size="3"> <br><br>
 
 
 
'''24, July 2013'''
 
 
Rubén Alcázar editor of Advances in Botany [http://www.hindawi.com/journals/abot/editors/ Editorial Board] <br>
 
'''February 2013'''
 
 
Rubén Alcázar guest editor of the research topic "Polyamines in stress and development"<br> in [http://www.frontiersin.org/Plant_Metabolism_and_Chemodiversity/researchtopics/Plant_polyamines_in_stress_and/1527 Frontiers in Plant Sci.]
 
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'''PREVIOUS ANNOUNCEMENTS'''
 
  
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* Our lab has started research activities as from 1st Dec 2012 and is recruting students interested in our research activities. Interested people should contact us directly.
 
* '''25.10.2012''' R.A. granted by Marie Curie Actions for the project DISEASENVIRON.
 
* '''25.10.2012'''  Review on new open access journal 'Metabolites' published. [http://www.mdpi.com/2218-1989/2/3/516 read]
 
*'''''08.10.2012''''' Interessat en realitzar la tesi doctoral o màster al nostre grup? Contacta per e-mail amb nosaltres.
 
*'''''04.10.2012''''' New lab webpage version released in OpenWetWare.
 
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[[Image:Announcement_alcazar.jpg |100px]] '''News and Announcements e-Board'''<br>
'''SEMINARS - Keep updated with our research''' <br><br>
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  NEWS
  Summer break until September. There are no seminars scheduled.
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  Master in Molecular Biotechnology (Trabajo Final de Máster) offers.
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[http://www.ub.edu/portal/web/farmacia/masters-universitaris/-/ensenyament/detallEnsenyament/483691/0 info]
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Contact us directly at ralcazar(at)ub.edu
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 +
  
Previous seminars: <br>
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''' ACADEMIC PRESS RELEASES'''<br>
'''16 April 12:30h'''<br>
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  [http://www.ub.edu/web/ub/en/menu_eines/noticies/2015/01/020.html? Alcázar Lab work highlighted by the University of Barcelona 20.01.15]<br>
  Location: Aula Magna, Facultat de Farmàcia, Universitat de Barcelona <br>
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  [http://www.ub.edu/noticies/cgi/event.pl?id=62490&noticiaub=FARMACIA Rubén Alcázar research highlighted by the Faculty of Pharmacy at UB, January 2015]<br>
  Avda Joan XXIII 27-31, 08028 Barcelona<br>
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  [http://sefv.net/files/sd_publicaciones/58.pdf Alcázar Lab work highlighted by the Bulletin of the Spanish Society of Plant Physiology, SEFV. January, 2015]<br>
  Title: Incompatibilitats genètiques del sistema immune de les plantes.<br>
+
  [http://www.mpipz.mpg.de/4042700/PM_Parker_2015 PLoS Genet 2014 highlight by Max Planck Institute, Cologne. 11.12.14.]<br>
  Language: Catalan <br><br>
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[http://www.ub.edu/web/ub/en/menu_eines/noticies/2013/11/063.html? Arabidopsis semidwarfs: the green revolution in nature] 02.12.2013. University of Barcelona.<br>
<font face="trebuchet ms" style="color:#000000" font size="2">
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[http://www.mpipz.mpg.de/5389/news_publication_619091 Hybrid plants with over-reactive immune system] 17.11.2010. Max Planck Society.
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<br>
 
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'''Address:'''
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Rubén Alcázar is Ramón y Cajal Researcher at the Department of Biology, Healthcare and Environment of the [http://www.ub.edu University of Barcelona].<br>
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<br>'''Research in Alcázar Lab is supported by:'''
 +
 
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<font face="calibri" style="color:#000000" font size="2"><br>
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* 7th Framework Programme. Marie Curie Career Integration Grant (DISEASENVIRON, PCIG10-GA-2011-303568) of the European Union.
 +
* Ramón y Cajal Program (RYC-2011-07847) of the Ministerio de Ciencia e Innovación (Spain).
 +
* BFU2013-41337-P grant of the Programa Estatal de Fomento de la Investigación Científica y Técnica de Excelencia (Ministerio de Economía y Competitividad, Spain).
  
Facultat de Farmàcia - Universitat de Barcelona (UB) <br>
 
Departament de Productes Naturals, Biologia Vegetal i Edafologia<br>
 
Unitat de Fisiologia Vegetal - Edifici A, 2a Planta <br>
 
Avda Joan XXIII 27-31, 08028 Barcelona<br>
 
Spain<br>
 
<br>
 
 
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Esta página web así como sus contenidos se ofrecen en inglés excepto el apartado +INFO dirigido al público
 
en general.<br>
 
Aquesta pàgina web així com els seus contiguts estan en anglès, exceptuant l'apartat +INFO dirigit al públic
 
en general.
 
 
<p>This wiki site is built under [http://www.openwetware.org Openwetware],  an open access movement promoting the sharing of information among researchers.</p>
 

Latest revision as of 01:53, 11 August 2017

Alcazarlab logo.jpg

**** New lab webpage hosted at University of Barcelona servers***
Please visit: http://www.ub.edu/portal/web/dp-bsma/stress


LogoUB .jpg
Dept. Biology, Healthcare & Environment
Section of Plant Physiology
Facultat de Farmàcia, Av. Joan XXIII 27-31
08028 Barcelona, Spain

<html><a href="http://www.revolvermaps.com/?target=enlarge&i=0ewrbw4fec7"><img src="//ra.revolvermaps.com/h/m/a/0/fff600/128/40/0ewrbw4fec7.png" width="156" height="100" alt="Map" style="border:0;"></a>


Dear visitor,

Welcome to the Molecular Genetics of Plant Stress Tolerance Lab (Ruben Alcazar & A.F. Tiburcio Labs) at the Department of Biology, Healthcare & Environment of the University of Barcelona.

We're a recently created joint research group that investigates the adaptation of plants to local environments. We focus on the evolutionary adaptation of plant populations to abiotic and biotic stresses, which are major challenges for plant survival under the current climate change predictions. Derived from our research, we investigate ways for improving stress protection.

For a more detailed view of our research, please have a look at our Research Projects and Scientific Publications sections. You can follow an updated list of our activities and publications in the NEWS section below. For any other enquires, do not hesitate to contact us directly.












1. POLYAMINE PERCEPTION AND SIGNALING

Polyamines.jpg


Our research laboratory has long-standing experience in the field of plant polyamines, for which we performed a number of omics approaches and established genetic evidence for their role in abiotic stress protection.


Our previous research pointed to interactions of polyamines with hormones and other stress-related metabolites. Our current goal is to investigate how polyamines are perceived by the plant, which early signaling components are involved, and how this is shaped by the environment.


We’re making use of background knowledge from different disciplines to gain insight into polyamine perception and signaling, for which little is known in plants. We’re making use of genetics of natural variation, reverse genetics, molecular biology and plant-microbe interactions to unravel how polyamines are sensed and how this relates to the local microbiota.


Our final goal is to provide novel approaches for crop protection against abiotic and biotic stresses.


Key words: stress tolerance, drought, salinity, freezing tolerance, priming, ROS, crop protection, microbiome, rhizosphere, polyamines, natural variation, transcriptional regulation, metabolon, modulon.


2. MOLECULAR EVOLUTION OF DISEASE RESISTANCE IN PLANTS


In our lab, we make use of the extensive natural variation of Arabidopsis thaliana populations to answer key fundamental questions:

  • How plants adapt to local environments including the microbiota?
  • How plants maintain variability of genes involved in pathogen recognition and to which extent this variability is caused by the interaction with pathogens?
  • How the environment manipulates immune responses? How this affects the above points?


To address these and other questions, we (and others) developed a new model for plant immunity studies based on the use of Arabidopsis immune-related incompatible hybrids. These are hybrids obtained by crosses of natural Arabidopsis accessions that exhibit constitutive activation of defense, stunted growth and sterility in the absence of pathogen challenge. Often, such phenotypes are temperature-dependent and suppressed at high temperature.


These genetic interactions might unravel molecular partners required for proper modulation of defense. Some of these cases are background-dependent and therefore, likely difficult to be observed in classical reference accessions.


Since some years, we're using the Ler / Kas-2 immune-related hybrid incompatibility as molecular model to answer some of the questions above. The Landsberg (from Gorzów Wielkopolski, Poland)/Kashmir-2 (from Kashmir mountains) incompatibility involves populations in Central Europe and Central Asia which enable to expand our analyses to population scales. We apply population genetics on top of our molecular and biochemical analyses.


Derived from our research, we attempt to provide new strategies for crop protection at medium to long-term.






Announcement alcazar.jpg News and Announcements e-Board

 NEWS
Master in Molecular Biotechnology (Trabajo Final de Máster) offers.
info
Contact us directly at ralcazar(at)ub.edu


ACADEMIC PRESS RELEASES

Alcázar Lab work highlighted by the University of Barcelona 20.01.15
Rubén Alcázar research highlighted by the Faculty of Pharmacy at UB, January 2015
Alcázar Lab work highlighted by the Bulletin of the Spanish Society of Plant Physiology, SEFV. January, 2015
PLoS Genet 2014 highlight by Max Planck Institute, Cologne. 11.12.14.
Arabidopsis semidwarfs: the green revolution in nature 02.12.2013. University of Barcelona.
Hybrid plants with over-reactive immune system 17.11.2010. Max Planck Society.



Rubén Alcázar is Ramón y Cajal Researcher at the Department of Biology, Healthcare and Environment of the University of Barcelona.



Research in Alcázar Lab is supported by:


  • 7th Framework Programme. Marie Curie Career Integration Grant (DISEASENVIRON, PCIG10-GA-2011-303568) of the European Union.
  • Ramón y Cajal Program (RYC-2011-07847) of the Ministerio de Ciencia e Innovación (Spain).
  • BFU2013-41337-P grant of the Programa Estatal de Fomento de la Investigación Científica y Técnica de Excelencia (Ministerio de Economía y Competitividad, Spain).