Difference between revisions of "Kim"

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[[Kim | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''HOME''' </font>]] &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
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[[Kim | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''HOME''' </font>]] &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
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[[Kim:Research | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''RESEARCH''' </font>]] &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
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[[Kim:Publications | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''PUBLICATIONS''' </font>]] &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
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[[Kim:Lab Members | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''PEOPLE''' </font>]] &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
[[Kim:Internal | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''INTERNAL''' </font>]] &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
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[[Kim:Hall_Of_Fame | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''HALL OF FAME''' </font>]] &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
[[Kim:Positions | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''POSITIONS''' </font>]] &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
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[[Kim:News | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''NEWS''' </font>]] &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
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[[Kim:Positions | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''POSITIONS''' </font>]] &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
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[[Kim:Outreach | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''OUTREACH''' </font>]] &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
[[Kim:Outreach | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''OUTREACH''' </font>]] &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;[[Kim:Contact | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''CONTACT''' </font>]] &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
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[[Kim:Internal | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''INTERNAL''' </font>]] &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
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[[Kim:Contact | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''CONTACT''' </font>]] &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
 
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<h3>Overview</h3>
 
<h3>Overview</h3>
<font size=3>Our research spans the disciplinary boundaries between biomaterials, nanotechnology, and cell mechanobiology with an emphasis on their applications to tissue engineering and regenerative medicine. Through the use of multiscale (nano/micro/meso) fabrication and integration tools, we focus on the development and applications of biomimetic cell culture models and functional tissue engineering constructs for high-throughput drug screening, stem cell-based therapies, disease diagnostics, and medical device development. Using engineered microenvironments in combination with quantitative live cell imaging approaches, we are also studying the interplay between mechanical and biochemical signaling in the regulation of cell function and fate decisions that are essential for tissue repair and regeneration following injury, and various developmental events. The ultimate goal of our research is to better understand complex cellular behavior in response to microenvironmental cues in normal, aging and disease states, to gain new mechanistic insights into the control of cell-tissue structure and function, and to develop multiscale regenerative technologies for improving human health. </font>
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Our research spans the disciplinary boundaries between nanotechnology, biomaterials, and mechanobiology with an emphasis on their applications to tissue engineering and regenerative medicine. Through the use of multi-scale (nano/micro/meso) fabrication and integration tools, we focus on the development and application of bio-inspired materials/devices and functional tissue engineering models for elucidating regenerative biology, drug screening, disease modeling, and stem cell-based therapies. Using engineered microenvironments in combination with quantitative live cell imaging approaches, we are also studying the intricate interactions between mechanical and biochemical signaling in the regulation of cell/tissue function and fate decisions that are essential for tumor progression and metastasis, tissue repair and regeneration following injury, and various developmental events. The ultimate goal of our research is to better understand complex cellular behavior in response to microenvironmental cues in normal, aging and disease states, to gain new mechanistic insights into the control of cell-tissue structure and function, and to develop multi-scale regenerative technologies for improving human health.  
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<h3>News</h3>  
 
<h3>News</h3>  
 
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* D. Kim was awarded an Muscular Dystrophy Association (MDA) research grant to develop techniques for growing muscle for use in transplantation into a mouse model of Duchenne muscular dystrophy and was featured on the [http://mda.org/research/gaag/dmd-deok-ho-kim-phd MDA website] (Apr. 2013)
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* Prof. Kim has been promoted to Associate Professor with Tenure! (09/2017)
* Daniel Lih has been awarded the Mary Gates Undergraduate Research Scholarship!
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* Kim lab has been awarded a NIH R01 grant! (02/2017)
* Hee Seok Yang, who was a post doc in the lab, has accepted an offer to start as a faculty member at the Dankook University in Korea. Congratulations! (Feb. 2013)
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* Peter Kim has been awarded the AHA Predoctoral Fellowship! (12/2014)
* Alex Jiao, Nicole Trosper, and Justin Lee win the Outstanding Paper Award at the 2013 ASME Global Congress on Nano Engineering for Medicine and Biology (Feb. 2013)
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* Cameron Nemeth has been given a BMES Undergraduate Design and Research Award and the Washington Research Foundation Fellowship. (Sept. 2013) [http://depts.washington.edu/bioe/cameron-nemeth-receives-bmes-award-wrf-fellowship/ Read more] 
* D. Kim was invited to join the editorial board of the [http://www.springer.com/engineering/electronics/journal/12213 Journal of Micro-Bio Robotics] as an Associate Editor (Jan. 2013)
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* Prof. Kim has been awarded the prestigious Young Investigator Award 2013 from the [http://ksea.org/index.php?option=com_content&view=article&id=521:2013yigwinners&catid=11:upcoming-events&Itemid=48 Korean-American Scientists and Engineers Association (KSEA)]. (06/2013)
* D. Kim joins the honorary Editorial Board of the [http://www.dovepress.com/honorary-editorial-board-international-journal-of-nanomedicine-edboard5 International Journal of Nanomedicine] (Jan. 2013)
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* Prof. Kim joined the editorial board of the [http://www.aspbs.com/jbn.html Journal of Biomedical Nanotechnology] as an Associate Editor. (05/ 2013)
* D. Kim joins the Editorial Board of the [http://digital-library.theiet.org/content/journals/iet-nbt IET Nanobiotechnology Journal]   (Jan. 2013)  
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* Kim Lab has been awarded an [http://mda.org/research/gaag/dmd-deok-ho-kim-phd Muscular Dystrophy Association (MDA) research grant] to develop bioengineering techniques for growing muscle for use in transplantation into a mouse model of Duchenne muscular dystrophy. (02/2013)
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<h3>Featured Publications</h3>  
 
<h3>Featured Publications</h3>  
 
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* A non-transcriptional role for HIF-1α as a direct inhibitor of DNA replication, Science Signaling, vol. 6, pp. ra10, 2013. [http://stke.sciencemag.org/content/vol6/issue262/cover.dtl '''(Featured as a Cover Article)''']  [http://stke.sciencemag.org/cgi/content/full/sigtrans;6/262/ra10 Article] [http://stke.sciencemag.org/cgi/content/full/sigtrans;6/262/pc5/DC1 Podcast]<br>
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* [http://pubs.rsc.org/en/content/articlelanding/2017/CC/C7CC01988B#!divAbstract Micro- and nano-patterned conductive graphene-PEG hybrid scaffolds for cardiac tissue engineering], Chemical  Communications (2017).
* Nanopatterned cardiac cell patches promote stem cell niche formation and myocardial regeneration, Integrative Biology, Vol. 4, Issue 9,pp. 1019-1033, 2012 [http://pubs.rsc.org/en/journals/journalissues/ib#!issueid=ib004009&type=current&issnprint=1757-9694 '''(Featured Cover Article)''']    [http://pubs.rsc.org/en/content/articlelanding/2012/ib/c2ib20067h Article]<br>
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* [http://www.nature.com/articles/srep29749 Multiscale cues drive collective cell migration], Scientific Reports (2016).
* Matrix rigidity controls endothelial differentiation and morphogenesis of cardiac precursors, Science Signaling, vol. 5, issue 227, p. ra41, 2012. [http://stke.sciencemag.org/content/vol5/issue227/cover.dtl '''(Featured as a Cover Article)''']  [http://stke.sciencemag.org/cgi/content/abstract/sigtrans;5/227/ra41 Article]
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* [http://www.nature.com/nmat/journal/v15/n7/full/nmat4586.html Directed migration of cancer cells by the graded texture of the underlying matrix], Nature Materials (2016). 
* Engineering neuronal growth cone to promote axon regeneration over inhibitory molecules, Proceedings of the National Academy of Sciences USA, vol. 108, pp. 5057-5062, 2011. [http://www.pnas.org/content/early/2011/03/03/1011258108.full.pdf+html Article]<BR>
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* [http://www.sciencedirect.com/science/article/pii/S014296121600082X Spatiotemporal control of cardiac anisotropy using dynamic nanotopographic cues], Biomaterials (2016).
* Biomimetic nanopatterns as enabling tools for analysis and control of live cells, Advanced Materials, 2010. [http://www.ncbi.nlm.nih.gov/pubmed/20803528 Pubmed], [http://www.hubmed.org/display.cgi?uids=20803528 Hubmed] <BR>
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* [http://pubs.acs.org/doi/abs/10.1021/nn4063962 Thermoresponsive nanofabricated substratum for the engineering of three-dimensional tissues with layer-by-layer architectural control], ACS Nano (2014). 
* Nanoscale cues regulate the structure and function of macroscopic cardiac tissue constructs, Proceedings of National Academy of Sciences USA, vol.107, pp. 565-570, 2010. [http://www.ncbi.nlm.nih.gov/pubmed/20018748 Article]  [http://www.nibib.nih.gov/HealthEdu/eAdvances/30July10 '''(Highlighted in the National Institute of Biomedical Imaging and Bioengineering)]'''
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* [http://www.nature.com/ncomms/2014/140602/ncomms4935/full/ncomms4935.html Printing three dimensional tissue analog with decellularized extracellular matrix bioink], Nature Communications (2014).
* Microengineered platforms for cell mechanobiology, Annual Review of Biomedical Engineering, vol. 11, pp.203-233, 2009. [http://www.ncbi.nlm.nih.gov/pubmed/19400708 Article]
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* [http://www.sciencedirect.com/science/article/pii/S0142961213013239 Nanopatterned muscle cell patches for enhanced myogenesis and dystrophin expression in a mouse model of muscular dystrophy], Biomaterials (2014).
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* [http://www.pnas.org/content/early/2011/03/03/1011258108.full.pdf+html Engineering neuronal growth cone to promote axon regeneration over inhibitory molecules], Proceedings of National Academy of Sciences USA (2011).
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* [http://www.pnas.org/content/107/2/565.long Nanoscale cues regulate the structure and function of macroscopic cardiac tissue constructs], Proceedings of National Academy of Sciences USA (2010).  
 
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<font size = 3> '''Our Sponsors''': <br>
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[[Image: nsf_Logo.jpg|100px|link=http://mda.org/]] &emsp;&emsp;
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[[Image: NIH banner.png|220px|link = http://www.nih.gov/]] &emsp;&emsp;
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[[Image: AHA.jpg|140px|link = http://www.heart.org/HEARTORG/]] &emsp;&emsp;
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[[Image: MDAlogo name.jpg|200px|link=http://mda.org/]] &emsp;&emsp;
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[[Image:MOTIE-logo.jpg|180px|link=http://www.mke.go.kr/language/eng/]] &emsp;&emsp; <br>
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[[Image: Coulter.jpg|100px|link =http://www.whcf.org/]]  &emsp;&emsp;
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[[Image: C4C.png|160px|link = http://depts.washington.edu/uwc4c/]] &emsp;&emsp;&emsp;&emsp; 
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[[Image: Lsdf_logo2.gif‎|140px|link = http://www.lsdfa.org/]] &emsp;&emsp;
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[[Image: UWlogo.jpg|220px|link = http://www.washington.edu/]] &emsp;&emsp;
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[[Image:KSEAlogo.jpg|220px|link = http://www.ksea.org/2013/]] &emsp;&emsp; <br>
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<div style="text-align: left;">[http://www2.clustrmaps.com/user/a76c219e http://www2.clustrmaps.com/stats/maps-no_clusters/www.openwetware.org-wiki-Kim-thumb.jpg] </div>
  
[http://www2.clustrmaps.com/user/a76c219e http://www2.clustrmaps.com/stats/maps-no_clusters/www.openwetware.org-wiki-Kim-thumb.jpg]
 
[[Image: MDAlogo name.jpg|150px]]
 
  
  
 
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Latest revision as of 19:13, 27 September 2017

Kimlab Banner.png

HOME       RESEARCH       PUBLICATIONS       PEOPLE       HALL OF FAME       NEWS       POSITIONS       OUTREACH       INTERNAL       CONTACT      

Overview

Our research spans the disciplinary boundaries between nanotechnology, biomaterials, and mechanobiology with an emphasis on their applications to tissue engineering and regenerative medicine. Through the use of multi-scale (nano/micro/meso) fabrication and integration tools, we focus on the development and application of bio-inspired materials/devices and functional tissue engineering models for elucidating regenerative biology, drug screening, disease modeling, and stem cell-based therapies. Using engineered microenvironments in combination with quantitative live cell imaging approaches, we are also studying the intricate interactions between mechanical and biochemical signaling in the regulation of cell/tissue function and fate decisions that are essential for tumor progression and metastasis, tissue repair and regeneration following injury, and various developmental events. The ultimate goal of our research is to better understand complex cellular behavior in response to microenvironmental cues in normal, aging and disease states, to gain new mechanistic insights into the control of cell-tissue structure and function, and to develop multi-scale regenerative technologies for improving human health.

News

  • Prof. Kim has been promoted to Associate Professor with Tenure! (09/2017)
  • Kim lab has been awarded a NIH R01 grant! (02/2017)
  • Peter Kim has been awarded the AHA Predoctoral Fellowship! (12/2014)
  • Cameron Nemeth has been given a BMES Undergraduate Design and Research Award and the Washington Research Foundation Fellowship. (Sept. 2013) Read more
  • Prof. Kim has been awarded the prestigious Young Investigator Award 2013 from the Korean-American Scientists and Engineers Association (KSEA). (06/2013)
  • Prof. Kim joined the editorial board of the Journal of Biomedical Nanotechnology as an Associate Editor. (05/ 2013)
  • Kim Lab has been awarded an Muscular Dystrophy Association (MDA) research grant to develop bioengineering techniques for growing muscle for use in transplantation into a mouse model of Duchenne muscular dystrophy. (02/2013)



Featured Publications


Our Sponsors:
Nsf Logo.jpg    link = http://www.nih.gov/    link = http://www.heart.org/HEARTORG/    MDAlogo name.jpg    MOTIE-logo.jpg   
link =http://www.whcf.org/    link = http://depts.washington.edu/uwc4c/      link = http://www.lsdfa.org/    link = http://www.washington.edu/    link = http://www.ksea.org/2013/