Karenliu

From OpenWetWare
Revision as of 02:24, 14 August 2013 by James Barrell (talk | contribs)
Jump to: navigation, search
The Liu Lab Department of Craniofacial Biology Kings College London
Home Research Publications Protocols & Etc. Lab Members Contact Us Links

Template:Div col

  • a
  • b
  • c
  • d
  • e
  • f
  • g
  • h

Template:Div col end

Welcome to the Liu lab!

We are interested in signal transduction in developmental biology.

In any intricate developmental process, the encoded genes are interpreted as myriad intercellular and intracellular interactions, all of which must occur at the right time and place. With this in mind, we are developing new methods to block or alter the activities of individual proteins in a drug-dependent manner. Our goal is to expand the repertoire of molecular tools available to developmental biologists. Rather than screen for small molecule-protein interactions we have chosen to use a directed approach to making chemically sensitive protein alleles, in which we use drug-dependent tags to regulate protein stability and localization.


The biological problem that we are interested in is the development of the neural crest and its derivatives, including the craniofacial skeleton. At present, we are developing chemical tools to study the roles of GSK-3 and Wnt signaling in the neural crest. We are using two model systems, the frog Xenopus laevis and the mouse. Xenopus embryos are abundant and live in an aquatic environment, allowing easy manipulation and drug accessibility; thus, we are using Xenopus to study early patterning and to rapidly test new tools. We then adapt these tools to mammalian systems. In the mouse, we are currently studying the development of the bony skull, using conventional and drug-dependent alleles of GSK-3β.


<wikionly>

Recent updates to the lab wiki

18 January 2018

 m   14:59  Endy Lab‎ (diff | hist) . . (0). . Reicker1 (talk | contribs) (News)

     14:46 

HughesLab:Publications‎‎ (3 changes | history) . . (+246). . [Scott A. Lewis‎; Erin Arant‎; Christina Hoffmann‎]

     

14:46

(cur | prev) . . (+195). . Scott A. Lewis (talk | contribs) (Publications)

     

08:29

(cur | prev) . . (-307). . Christina Hoffmann (talk | contribs) (Publications)

     

06:24

(cur | prev) . . (+358). . Erin Arant (talk | contribs) (Publications)

     14:39 

HughesLab:Research‎‎ (5 changes | history) . . (+4,967). . [Erin Arant‎ (2×); Scott A. Lewis‎ (3×)]

     

14:39

(cur | prev) . . (+2,347). . Scott A. Lewis (talk | contribs)

     

14:32

(cur | prev) . . (-2,040). . Scott A. Lewis (talk | contribs)

     

14:08

(cur | prev) . . (+2,063). . Scott A. Lewis (talk | contribs)

     

09:01

(cur | prev) . . (+1). . Erin Arant (talk | contribs) (Transcriptional profiling of skeletal muscle)

     

07:32

(cur | prev) . . (+2,596). . Erin Arant (talk | contribs)

     14:19 

(Upload log). .

[Scott A. Lewis‎; Elizabeth M. Topp‎; Erin Arant‎ (2×); Benjamin Blount‎ (2×)]

     

14:19

. . Scott A. Lewis (talk | contribs) uploaded File:ExpressionDB Fig1.png

     

10:47

. . Elizabeth M. Topp (talk | contribs) uploaded File:ToppLab 2017.jpg

     

09:04

. . Erin Arant (talk | contribs) uploaded a new version of File:ETFigure 1.png

     

09:02

. . Erin Arant (talk | contribs) uploaded File:ETFigure 1.png

     

07:06

. . Benjamin Blount (talk | contribs) uploaded File:Ben-150x150.jpg

     

07:04

. . Benjamin Blount (talk | contribs) uploaded File:Ben-300x300.jpg

     14:11  User:Scott A. Lewis‎ (diff | hist) . . (+9). . Scott A. Lewis (talk | contribs)

     11:23 

User:Samantha J. McCabe‎‎ (2 changes | history) . . (+95). . [Samantha J. McCabe‎ (2×)]

     

11:23

(cur | prev) . . (+15). . Samantha J. McCabe (talk | contribs) (Research Interests)

 m   

11:20

(cur | prev) . . (+80). . Samantha J. McCabe (talk | contribs) (Honors and Awards)

     11:20 

(User creation log). .

[Yar‎ (17×)]

     

11:20

. . User account Gsandoval16 (talk | contribs) was created by Yar (talk | contribs) and password was sent by email ‎

     

11:20

. . User account NicK K (talk | contribs) was created by Yar (talk | contribs) and password was sent by email ‎

     

11:20

. . User account EHALHOWS (talk | contribs) was created by Yar (talk | contribs) and password was sent by email ‎

     

11:20

. . User account Dawill27 (talk | contribs) was created by Yar (talk | contribs) and password was sent by email ‎

     

11:20

. . User account Iaheath (talk | contribs) was created by Yar (talk | contribs) and password was sent by email ‎

     

11:20

. . User account Cngarza1 (talk | contribs) was created by Yar (talk | contribs) and password was sent by email ‎

     

11:20

. . User account Annaavila (talk | contribs) was created by Yar (talk | contribs) and password was sent by email ‎

     

11:20

. . User account Zwirtes (talk | contribs) was created by Yar (talk | contribs) and password was sent by email ‎

     

11:20

. . User account Jameskcrichton (talk | contribs) was created by Yar (talk | contribs) and password was sent by email ‎

     

11:20

. . User account Dinubilotay99 (talk | contribs) was created by Yar (talk | contribs) and password was sent by email ‎

     

11:20

. . User account Kcsmit20 (talk | contribs) was created by Yar (talk | contribs) and password was sent by email ‎

     

11:20

. . User account Msobrado (talk | contribs) was created by Yar (talk | contribs) and password was sent by email ‎

     

11:20

. . User account Varvizu1 (talk | contribs) was created by Yar (talk | contribs) and password was sent by email ‎

     

11:20

. . User account Mtryder (talk | contribs) was created by Yar (talk | contribs) and password was sent by email ‎

     

11:20

. . User account Matt jacob wallace (talk | contribs) was created by Yar (talk | contribs) and password was sent by email ‎

     

11:20

. . User account Claudyhenrix (talk | contribs) was created by Yar (talk | contribs) and password was sent by email ‎

     

11:20

. . User account Citizen 88 (talk | contribs) was created by Yar (talk | contribs) and password was sent by email ‎

     11:14 

Topp:Lab Members‎‎ (2 changes | history) . . (-7). . [Elizabeth M. Topp‎ (2×)]

     

11:14

(cur | prev) . . (-2). . Elizabeth M. Topp (talk | contribs)

     

11:13

(cur | prev) . . (-5). . Elizabeth M. Topp (talk | contribs)

N    10:30  BME100 s2018:Group6 W0800 L1‎ (diff | hist) . . (+2,502). . Dadesimo (talk | contribs) (Created page with "{|{{table}} width="800" |- |style="background-color: #EEE"|128px<span style="font-size:22px;"> BME 100 Spring 2018</span> |style="background-col...")

     07:30 

HughesLab:MuscleDB‎‎ (2 changes | history) . . (+394). . [Michael E Hughes‎; Erin Arant‎]

     

07:30

(cur | prev) . . (+1). . Michael E Hughes (talk | contribs) (MuscleDB)

     

06:40

(cur | prev) . . (+393). . Erin Arant (talk | contribs) (MuscleDB)

     07:07 

User:Benjamin Blount‎‎ (5 changes | history) . . (+2,125). . [Benjamin Blount‎ (5×)]

     

07:07

(cur | prev) . . (0). . Benjamin Blount (talk | contribs)

     

07:06

(cur | prev) . . (-42). . Benjamin Blount (talk | contribs)

     

07:00

(cur | prev) . . (+39). . Benjamin Blount (talk | contribs) (Contact Info)

     

06:59

(cur | prev) . . (+991). . Benjamin Blount (talk | contribs) (Research interests)

     

06:54

(cur | prev) . . (+1,137). . Benjamin Blount (talk | contribs) (Publications)

     04:57 

Harvard:Biophysics 101/2018‎‎ (2 changes | history) . . (+208). . [Geochurch‎ (2×)]

     

04:57

(cur | prev) . . (-1). . Geochurch (talk | contribs)

     

04:55

(cur | prev) . . (+209). . Geochurch (talk | contribs)

17 January 2018

     16:51  Lee:Publications‎ (diff | hist) . . (+191). . Wooin Lee (talk | contribs) (2018)
     15:35  User:Korey Griffin‎ (diff | hist) . . (-2). . Korey Griffin (talk | contribs) (Methods & Techniques)
     15:31  Griffin:Western Blot Optimization‎ (diff | hist) . . (+67). . Korey Griffin (talk | contribs)
</wikionly>

<nonwikionly> This page was created using Open Wetware.</nonwikionly>