Difference between revisions of "Karenliu"

From OpenWetWare
Line 4: Line 4:
  
 
==Welcome to the Liu lab!==
 
==Welcome to the Liu lab!==
 
 
  
 
We are interested in signal transduction in developmental biology.
 
We are interested in signal transduction in developmental biology.

Revision as of 04:26, 14 August 2013

The Liu Lab Department of Craniofacial Biology Kings College London
Home Research Publications Protocols & Etc. Lab Members Contact Us Links

Welcome to the Liu lab!

We are interested in signal transduction in developmental biology.

In any intricate developmental process, the encoded genes are interpreted as myriad intercellular and intracellular interactions, all of which must occur at the right time and place. With this in mind, we are developing new methods to block or alter the activities of individual proteins in a drug-dependent manner. Our goal is to expand the repertoire of molecular tools available to developmental biologists. Rather than screen for small molecule-protein interactions we have chosen to use a directed approach to making chemically sensitive protein alleles, in which we use drug-dependent tags to regulate protein stability and localization.


The biological problem that we are interested in is the development of the neural crest and its derivatives, including the craniofacial skeleton. At present, we are developing chemical tools to study the roles of GSK-3 and Wnt signaling in the neural crest. We are using two model systems, the frog Xenopus laevis and the mouse. Xenopus embryos are abundant and live in an aquatic environment, allowing easy manipulation and drug accessibility; thus, we are using Xenopus to study early patterning and to rapidly test new tools. We then adapt these tools to mammalian systems. In the mouse, we are currently studying the development of the bony skull, using conventional and drug-dependent alleles of GSK-3β.


<wikionly>

Recent updates to the lab wiki

25 September 2018

N    10:45 

User:Jasmine Nazaire/Notebook/Clay Beads 2‎‎ (4 changes | history) . . (+1,703). . [Jasmine Nazaire‎ (4×)]

     

10:45

(cur | prev) . . (-1). . Jasmine Nazaire (talk | contribs) (Description)

     

09:47

(cur | prev) . . (-213). . Jasmine Nazaire (talk | contribs) (Notes)

     

09:47

(cur | prev) . . (+343). . Jasmine Nazaire (talk | contribs) (Project Description/Abstract)

N    

09:23

(cur | prev) . . (+1,574). . Jasmine Nazaire (talk | contribs) (Autocreated Lab Notebook name=User:Jasmine Nazaire/Notebook/Clay Beads 2, content from MediaWiki:ProjectContentDefault)

     10:44 

User:Jasmine Nazaire/Notebook/Clay Beads‎‎ (7 changes | history) . . (-222). . [Jasmine Nazaire‎ (7×)]

     

10:44

(cur | prev) . . (+1). . Jasmine Nazaire (talk | contribs) (Notes)

     

10:44

(cur | prev) . . (+2). . Jasmine Nazaire (talk | contribs) (Description)

     

09:19

(cur | prev) . . (+86). . Jasmine Nazaire (talk | contribs) (Objective)

     

09:19

(cur | prev) . . (-167). . Jasmine Nazaire (talk | contribs) (Notes)

     

09:19

(cur | prev) . . (+67). . Jasmine Nazaire (talk | contribs) (Data)

     

09:17

(cur | prev) . . (+67). . Jasmine Nazaire (talk | contribs) (Data)

     

09:15

(cur | prev) . . (-278). . Jasmine Nazaire (talk | contribs) (Project Description/Abstract)

N    10:44 

User:Jasmine Nazaire/Notebook/Clay Beads 3‎‎ (5 changes | history) . . (+1,863). . [Jasmine Nazaire‎ (5×)]

     

10:44

(cur | prev) . . (+1). . Jasmine Nazaire (talk | contribs) (Description)

     

10:43

(cur | prev) . . (+215). . Jasmine Nazaire (talk | contribs) (Notes)

     

10:39

(cur | prev) . . (+606). . Jasmine Nazaire (talk | contribs) (Description)

     

10:20

(cur | prev) . . (-533). . Jasmine Nazaire (talk | contribs) (Project Description/Abstract)

N    

09:49

(cur | prev) . . (+1,574). . Jasmine Nazaire (talk | contribs) (Autocreated Lab Notebook name=User:Jasmine Nazaire/Notebook/Clay Beads 3, content from MediaWiki:ProjectContentDefault)

     09:49 

User:Jasmine Nazaire‎‎ (3 changes | history) . . (+211). . [Jasmine Nazaire‎ (3×)]

     

09:49

(cur | prev) . . (+71). . Jasmine Nazaire (talk | contribs)

     

09:27

(cur | prev) . . (+71). . Jasmine Nazaire (talk | contribs)

     

09:06

(cur | prev) . . (+69). . Jasmine Nazaire (talk | contribs)

N    09:49  User:Jasmine Nazaire/Notebook/Clay Beads 3/Entry Base‎ (diff | hist) . . (+950). . Jasmine Nazaire (talk | contribs) (Autocreated Lab Notebook name=User:Jasmine Nazaire/Notebook/Clay Beads 3/Entry Base, content from MediaWiki:EntryContentDefault)

     09:29 

(User creation log). .

[Yar‎ (3×)]

     

09:29

. . User account Konate (talk | contribs) was created by Yar (talk | contribs) and password was sent by email ‎

     

09:29

. . User account Lowensev (talk | contribs) was created by Yar (talk | contribs) and password was sent by email ‎

     

09:29

. . User account Dohaz (talk | contribs) was created by Yar (talk | contribs) and password was sent by email ‎

N    09:23  User:Jasmine Nazaire/Notebook/Clay Beads 2/Entry Base‎ (diff | hist) . . (+950). . Jasmine Nazaire (talk | contribs) (Autocreated Lab Notebook name=User:Jasmine Nazaire/Notebook/Clay Beads 2/Entry Base, content from MediaWiki:EntryContentDefault)

     09:18 

(Upload log). .

[Jasmine Nazaire‎ (2×)]

     

09:18

. . Jasmine Nazaire (talk | contribs) uploaded File:IMG 3139.jpg

     

09:15

. . Jasmine Nazaire (talk | contribs) uploaded File:IMG 3140.jpg

     09:06 (Move log) . . Jasmine Nazaire (talk | contribs) moved page User:Jasmine Nazaire/Notebook/12/09/2018 Clay Beads to User:Jasmine Nazaire/Notebook/Clay Beads
N    09:03  User:Jasmine Nazaire/Notebook/12/09/2018 Clay Beads/Entry Base‎ (diff | hist) . . (+950). . Jasmine Nazaire (talk | contribs) (Autocreated Lab Notebook name=User:Jasmine Nazaire/Notebook/12/09/2018 Clay Beads/Entry Base, content from MediaWiki:EntryContentDefault)
N    09:03  User:Jasmine Nazaire/Notebook/12/09/2018 Clay Beads‎ (diff | hist) . . (+1,574). . Jasmine Nazaire (talk | contribs) (Autocreated Lab Notebook name=User:Jasmine Nazaire/Notebook/12/09/2018 Clay Beads, content from MediaWiki:ProjectContentDefault)

     02:52 

User:Matthew Todd‎‎ (4 changes | history) . . (+82). . [Matthew Todd‎ (4×)]

     

02:52

(cur | prev) . . (+10). . Matthew Todd (talk | contribs) (Research interests)

     

02:51

(cur | prev) . . (+58). . Matthew Todd (talk | contribs) (Education)

     

02:50

(cur | prev) . . (+110). . Matthew Todd (talk | contribs) (Short Bio)

     

02:48

(cur | prev) . . (-96). . Matthew Todd (talk | contribs) (Contact Info)

     02:45  Todd‎ (diff | hist) . . (+61). . Matthew Todd (talk | contribs)

24 September 2018

     21:31 

HoatlinCONJ606:Schedule 2018‎‎ (4 changes | history) . . (+1,364). . [Maureen E. Hoatlin‎ (4×)]

     

21:31

(cur | prev) . . (+541). . Maureen E. Hoatlin (talk | contribs) (Week-by-Week Schedule Summary)

     

21:16

(cur | prev) . . (+369). . Maureen E. Hoatlin (talk | contribs) (Week-by-Week Schedule Summary)

     

20:55

(cur | prev) . . (+386). . Maureen E. Hoatlin (talk | contribs) (Week-by-Week Schedule Summary)

     

20:36

(cur | prev) . . (+68). . Maureen E. Hoatlin (talk | contribs) (Week-by-Week Schedule Summary)

     20:32 

HoatlinCONJ606:Materials 2018‎‎ (5 changes | history) . . (+19). . [Maureen E. Hoatlin‎ (5×)]

     

20:32

(cur | prev) . . (+6). . Maureen E. Hoatlin (talk | contribs) (Evaluation Forms)

     

20:15

(cur | prev) . . (+8). . Maureen E. Hoatlin (talk | contribs) (Evaluation Forms)

     

20:14

(cur | prev) . . (0). . Maureen E. Hoatlin (talk | contribs) (Evaluation Forms)

     

20:14

(cur | prev) . . (+61). . Maureen E. Hoatlin (talk | contribs) (Evaluation Forms)

     

20:09

(cur | prev) . . (-56). . Maureen E. Hoatlin (talk | contribs) (Evaluation Forms)

     20:12 (Upload log) . . Maureen E. Hoatlin (talk | contribs) uploaded File:HoatlinCONJ606MCDL eval.PNG(updated DL AND MC)

     20:06 

CONJ606:People 2018‎‎ (2 changes | history) . . (-375). . [Maureen E. Hoatlin‎ (2×)]

     

20:06

(cur | prev) . . (-4). . Maureen E. Hoatlin (talk | contribs) (Instructors)

     

20:05

(cur | prev) . . (-371). . Maureen E. Hoatlin (talk | contribs) (Instructors)

     18:06 

(User creation log). .

[Yar‎ (3×)]

     

18:06

. . User account Monamh (talk | contribs) was created by Yar (talk | contribs) and password was sent by email ‎

     

18:06

. . User account Coulterf (talk | contribs) was created by Yar (talk | contribs) and password was sent by email ‎

     

18:06

. . User account Heimt (talk | contribs) was created by Yar (talk | contribs) and password was sent by email ‎

     14:39  Tomlinson:Lab Members‎ (diff | hist) . . (+1). . Ryan E. Tomlinson (talk | contribs) (Gabriella Fioravanti)
</wikionly>

<nonwikionly> This page was created using Open Wetware.</nonwikionly>