Difference between revisions of "Karenliu"

From OpenWetWare
Jump to: navigation, search
Line 1: Line 1:
 
{{Template:KarenLiu}}
 
{{Template:KarenLiu}}
 
<center>
 
<center>
<div style="text-align:left;padding: 10px; width: 824px;border-style:solid;border-color:#000;border-width:3px">
+
<div style="text-align:left;padding: 10px; width: 824px;border-style:solid;border-color:#000;border-width:3px;border-radius:1em">
  
 
==Welcome to the Liu lab!==
 
==Welcome to the Liu lab!==

Revision as of 05:54, 8 August 2013

The Liu Lab Department of Craniofacial Biology Kings College London
Home Research Publications Protocols & Etc. Lab Members Contact Us Links

Welcome to the Liu lab!

We are interested in signal transduction in developmental biology.

In any intricate developmental process, the encoded genes are interpreted as myriad intercellular and intracellular interactions, all of which must occur at the right time and place. With this in mind, we are developing new methods to block or alter the activities of individual proteins in a drug-dependent manner. Our goal is to expand the repertoire of molecular tools available to developmental biologists. Rather than screen for small molecule-protein interactions we have chosen to use a directed approach to making chemically sensitive protein alleles, in which we use drug-dependent tags to regulate protein stability and localization.


The biological problem that we are interested in is the development of the neural crest and its derivatives, including the craniofacial skeleton. At present, we are developing chemical tools to study the roles of GSK-3 and Wnt signaling in the neural crest. We are using two model systems, the frog Xenopus laevis and the mouse. Xenopus embryos are abundant and live in an aquatic environment, allowing easy manipulation and drug accessibility; thus, we are using Xenopus to study early patterning and to rapidly test new tools. We then adapt these tools to mammalian systems. In the mouse, we are currently studying the development of the bony skull, using conventional and drug-dependent alleles of GSK-3β.


<wikionly>

Recent updates to the lab wiki

25 February 2018

     00:16  Lee:Publications‎ (diff | hist) . . (+16). . Wooin Lee (talk | contribs) (2018)

24 February 2018

     21:23  Park Lab :Lab Members‎ (diff | hist) . . (+1). . Jeewoong Lee (talk | contribs) (Former Lab Members)

     11:54 

User:Gareth Trubl‎‎ (7 changes | history) . . (+2,318). . [Gtrubl‎ (7×)]

     

11:54

(cur | prev) . . (+57). . Gtrubl (talk | contribs) (Awards)

     

11:53

(cur | prev) . . (+4). . Gtrubl (talk | contribs) (Teaching, Outreach, & other experiences)

     

11:53

(cur | prev) . . (+14). . Gtrubl (talk | contribs) (Teaching, Outreach, & other experiences)

     

11:52

(cur | prev) . . (+2). . Gtrubl (talk | contribs) (Conference Proceedings)

     

10:49

(cur | prev) . . (+1,833). . Gtrubl (talk | contribs) (Conference Proceedings)

     

10:11

(cur | prev) . . (+11). . Gtrubl (talk | contribs) (Publications)

     

10:09

(cur | prev) . . (+397). . Gtrubl (talk | contribs) (Publications)

     10:41  CHEM-ENG590E:Wiki Textbook‎ (diff | hist) . . (+61). . AB18 (talk | contribs) (Chapter 4 - Flow Control and Mixing)
     00:18  Duedu Lab‎ (diff | hist) . . (+195). . Kwabena (talk | contribs) (News)

23 February 2018

N    21:14 

Surface Wetting - Chris Ortins‎‎ (2 changes | history) . . (+1,564). . [Cortins‎ (2×)]

     

21:14

(cur | prev) . . (+916). . Cortins (talk | contribs)

N    

20:55

(cur | prev) . . (+648). . Cortins (talk | contribs) (Created page with "{{Template:CHEM-ENG590E}} =Surface Wetting= Surface wetting is the ability of a liquid to spread across a solid and maintain contact as a result of intermolecular forces. To m...")

     21:00 

3D Printing Technologies - Mitchell Culler‎‎ (4 changes | history) . . (+3,488). . [Mculler‎ (4×)]

     

21:00

(cur | prev) . . (+7). . Mculler (talk | contribs)

     

21:00

(cur | prev) . . (+7). . Mculler (talk | contribs)

     

21:00

(cur | prev) . . (+250). . Mculler (talk | contribs)

     

20:53

(cur | prev) . . (+3,224). . Mculler (talk | contribs)

     20:55 

CHEM-ENG590E:Wiki Textbook‎‎ (2 changes | history) . . (+68). . [Haoxic‎; Cortins‎]

     

20:55

(cur | prev) . . (+37). . Cortins (talk | contribs) (Chapter 4 - Flow Control and Mixing)

     

20:30

(cur | prev) . . (+31). . Haoxic (talk | contribs) (Chapter 1 - Microfabrication)

     20:52 

Droplet Microfluidics: T-Junction - Lina Wu‎‎ (3 changes | history) . . (+7,734). . [Lina Wu‎ (3×)]

     

20:52

(cur | prev) . . (+122). . Lina Wu (talk | contribs)

     

20:45

(cur | prev) . . (-5). . Lina Wu (talk | contribs) (T-Junction)

     

20:43

(cur | prev) . . (+7,617). . Lina Wu (talk | contribs)

     20:49 

(Upload log). .

[Stanleychenrhs‎; Lina Wu‎ (2×)]

     

20:49

. . Lina Wu (talk | contribs) uploaded File:CrossFlowModes.png(Modes of droplet generation)

     

20:44

. . Lina Wu (talk | contribs) uploaded File:T-junction.png(T-junction)

     

19:51

. . Stanleychenrhs (talk | contribs) uploaded a new version of File:SAMIMS.png

N    20:48 

Bonding Surface - Xi Hao‎‎ (5 changes | history) . . (+6,034). . [Haoxic‎ (5×)]

     

20:48

(cur | prev) . . (-44). . Haoxic (talk | contribs) (Ultraviolet (UV)–Ozone Treatment)

     

20:42

(cur | prev) . . (-49). . Haoxic (talk | contribs) (Ultraviolet (UV)–Ozone Treatment)

     

20:31

(cur | prev) . . (+6,127). . Haoxic (talk | contribs)

     

20:31

(cur | prev) . . (-6,127). . Haoxic (talk | contribs) (Blanked the page)

N    

20:30

(cur | prev) . . (+6,127). . Haoxic (talk | contribs) (Created page with "{{Template:CHEM-ENG590E}} =Bonding Surfaces= ==Introduction== Bonding surfaces is a process that bonds two surfaces to assemble them into a complete unit. Bonding Surfaces is...")

     20:27 

User:Haoxic‎‎ (3 changes | history) . . (+1,238). . [Haoxic‎ (3×)]

     

20:27

(cur | prev) . . (+720). . Haoxic (talk | contribs) (Crosslinking)

     

19:52

(cur | prev) . . (0). . Haoxic (talk | contribs) (Adhesives)

     

19:51

(cur | prev) . . (+518). . Haoxic (talk | contribs) (Ultraviolet (UV)–Ozone Treatment)

     20:12 

Solvent Assisted Micromolding (SAMIM) - Stanley Chen‎‎ (16 changes | history) . . (+895). . [Stanleychenrhs‎ (16×)]

     

20:12

(cur | prev) . . (+28). . Stanleychenrhs (talk | contribs) (Background: Solvent-Assisted Micromolding (SAMIM))

     

20:07

(cur | prev) . . (+88). . Stanleychenrhs (talk | contribs) (Challenges Facing SAMIM)

     

19:56

(cur | prev) . . (-51). . Stanleychenrhs (talk | contribs) (Current Applications)

     

19:55

(cur | prev) . . (-65). . Stanleychenrhs (talk | contribs) (Challenges Facing SAMIM)

     

19:55

(cur | prev) . . (+1). . Stanleychenrhs (talk | contribs) (Motivation)

     

19:55

(cur | prev) . . (-53). . Stanleychenrhs (talk | contribs) (Motivation)

     

19:54

(cur | prev) . . (+4). . Stanleychenrhs (talk | contribs) (Background: Solvent-Assisted Micromolding (SAMIM))

     

19:54

(cur | prev) . . (-55). . Stanleychenrhs (talk | contribs) (Background: Solvent-Assisted Micromolding (SAMIM))

     

19:53

(cur | prev) . . (0). . Stanleychenrhs (talk | contribs) (Background: Solvent-Assisted Micromolding (SAMIM))

     

19:52

(cur | prev) . . (0). . Stanleychenrhs (talk | contribs) (Background: Solvent-Assisted Micromolding (SAMIM))

     

19:47

(cur | prev) . . (+188). . Stanleychenrhs (talk | contribs) (References)

     

19:44

(cur | prev) . . (+382). . Stanleychenrhs (talk | contribs) (References)

     

19:38

(cur | prev) . . (+1). . Stanleychenrhs (talk | contribs) (References)

     

19:38

(cur | prev) . . (+242). . Stanleychenrhs (talk | contribs) (References)

     

19:34

(cur | prev) . . (+168). . Stanleychenrhs (talk | contribs) (References)

     

19:30

(cur | prev) . . (+17). . Stanleychenrhs (talk | contribs) (Current Applications)

N    19:51  Dry Etching - Kevin Lang‎ (diff | hist) . . (+5,544). . Klang (talk | contribs) (Created page with "{{Template:CHEM-ENG590E}} Image:Etching-7-638.jpeg|250px|right|thumbnail|'''Figure 1''' Depiction of plasma etching diagram with plasma between both electrodes removing subs...")
</wikionly>

<nonwikionly> This page was created using Open Wetware.</nonwikionly>