Kaifu

Contact Info

Kaifu Chen

• Kaifu Chen
• Dan L. Duncan Cancer Center,Department of Molecular and Cellular Biology, Baylor College of Medicine
• 1 Baylor Plaza, suite 450A, Houston, Texas,77030.
• kaifuc at bcm dot edu

Education

• 2009, PhD of Genomics and bioinformatics, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China.
• 2004, BS of Biophysics, Institute of Physics, Nankai University, Tianjin, China.

Experience

• 2009 - present, Postdoctorial Associate, Baylor College of Medicine, Houston, Texas, USA.
• 2008 - 2009, Research Associate, KACST, Riyadh, Saudi Arabia.
• 2004 - 2008, Beijing Genomics Institute, Beijing, China.

Research interests

1. Gene regulation
2. Chromatin organization and modification
3. Genomics & Epigenomics

Publication

* first or co-first authorship

1. Li Z, Gadue P, Chen K, Tuteja G, Schug J, Li W, Kaestner KH: Foxa2 and H2A.Z Mediate Nucleosome Depletion during Embryonic Stem Cell Differentiation. Cell (2012) Accepted.
2. Chen K*, Wilson MA*, Hirsch C, Watson A, Liang S, Lu Y, Li W, Dent S: Stabilization of the Promoter Nucleosomes in Nucleosome Free Region by the Yeast Ssn6-Tup1 Corepressor. Genome Res. (2012) Accepted.
3. Chen, X., Cui, D., Papusha, A., Zhang, X., Chu, C., Tang, J., Chen, K., Pan, X., Ira, G., The Fun30 nucleosome remodeller promotes resection of DNA double-strand break ends (2012). The Fun30 nucleosome remodeller promotes resection of DNA double-strand break ends. Nature. doi:10.1038/nature11355
4. Barber, M. F., Michishita-Kioi, E., Xi, Y., Tasselli, L., Kioi, M., Moqtaderi, Z., Tennen, R. I., Chen, K., et al. (2012). SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation. Nature. doi:10.1038/nature11043
5. Huang Z, Srinivasan S, Zhang J, Chen K, Li Y, Li W, Quiocho FA, Pan X: Discovering thiamine transporters as targets of chloroquine using a novel functional genomics strategy. PLOS Genetics (2012) Accepted
6. Badeaux, A. I., Yang, Y., Cardenas, K., Vemulapalli, V., Chen, K., Kusewitt, D., Richie, E., et al. (2012). Loss of the methyl lysine effector protein PHF20 impacts the expression of genes regulated by the lysine acetyltransferase MOF. The Journal of biological chemistry, 287(1), 429–437. doi:10.1074/jbc.M111.271163
7. Kuo, A. J.*, Cheung, P.*, Chen, K*., Zee, B. M., Kioi, M., Lauring, J., Xi, Y., et al. (2011). NSD2 Links Dimethylation of Histone H3 at Lysine 36 to Oncogenic Programming. Molecular cell, 44(4), 609–620. Elsevier. doi:10.1016/j.molcel.2011.08.042
8. Huang, Z., Chen, K., Xu, T., Zhang, J., Li, Y., Li, W., Agarwal, A. K., et al. (2011). Sampangine inhibits heme biosynthesis in both yeast and human. Eukaryotic cell, 10(11), 1536–1544. doi:10.1128/EC.05170-11
9. Ma, L., Chen, K., Meng, Q., Liu, Q., Tang, P., Hu, S., & Yu, J. (2011). An evolutionary analysis of trypanosomatid GP63 proteases. Parasitology research. doi:10.1007/s00436-011-2348-x
10. Meng, Q., Chen, K., Ma, L., Hu, S., & Yu, J. (2011). A systematic identification of Kolobok superfamily transposons in Trichomonas vaginalis and sequence analysis on related transposases. Journal of genetics and genomics. 38(2), 63–70. doi:10.1016/j.jcg.2011.01.003
11. Chen, K*., Wang, L., Yang, M., Liu, J., Xin, C., Hu, S., & Yu, J. (2010). Sequence signatures of nucleosome positioning in Caenorhabditis elegans. Genomics, proteomics & bioinformatics, 8(2), 92–102. doi:10.1016/S1672-0229(10)60010-1
12. Yang, M., Zhang, X., Liu, G., Yin, Y., Chen, K., Yun, Q., Zhao, D., et al. (2010). The complete chloroplast genome sequence of date palm (Phoenix dactylifera L.) PloS one, 5(9), e12762. doi:10.1371/journal.pone.0012762
13. Chen, K*., Meng, Q., Ma, L., Liu, Q., Tang, P., Chiu, C., Hu, S., et al. (2008). A novel DNA sequence periodicity decodes nucleosome positioning. Nucleic acids research, 36(19), 6228–6236. doi:10.1093/nar/gkn626

openwetware