Josh Michener

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Josh Michener


  • PhD, 2012, Bioengineering at Caltech
  • S.B. 2006, Chemical Engineering and Biology at MIT

Lab history

  • Postdoc in the Marx Lab, Harvard Department of Organismic and Evolutionary Biology
  • Graduate student in the Smolke Lab, Caltech/Stanford Bioengineering. Collaborated with Frances Arnold (Caltech ChemE) and Jens Nielsen (Chalmers Systems Bio)
  • UROP in the Endy Lab at MIT

Contact Info

Josh Michener
Bioengineering - Smolke Lab
Y2E2-B07, MC 4200
473 Via Ortega
Stanford, CA 94305



My research focuses on the combination of rational and evolutionary methods to build, analyze, and optimize metabolic pathways.


  • Michener JK and Smolke CD. High-throughput enzyme evolution in Saccharomyces cerevisiae using a synthetic RNA switch. Metab Eng. 2012 Jul;14(4):306-16. [1]
  • Michener JK, Thodey K, Liang JC, Smolke CD. Applications of genetically-encoded biosensors for the construction and control of biosynthetic pathways. Metab Eng. 2012 May;14(3):212-22. [2]